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Azabicyclo[3.1.0]hexane-1-ols as frameworks for the asymmetric synthesis of biologically active compounds

Tetrahedron Letters, 2007
Azabicyclo[3.1.0]hexane-1-ols, easily obtained by Ti(IV)-mediated cyclopropanation of amino acid derivatives, constitute versatile, and unprecedented intermediates for the asymmetric synthesis of pharmacologically active products. Indeed, through selective rearrangement, these compounds undergo unusual ring cleavage to lead to pyrrolidinones.
Regis Guillot, Jean Ollivier
exaly   +2 more sources

New compounds: Preparation of Oxime Esters from 1-Azabicyclo[4.4.0]decane-4-one

Journal of Pharmaceutical Sciences, 1971
The synthesis of two new oxime esters is described. Preliminary results of pharmacological tests are also reported.
R V, Saenz, R A, Crochet
exaly   +3 more sources

Piperidines and Azabicyclo Compounds. I. Via Michael Condensations

Journal of the American Chemical Society, 1950
Noel F Albertson
exaly   +2 more sources

The Synthesis And Properties Of 9-azabicyclo (3.3.1)nonane Compounds.

1974
PhD ; Organic chemistry ; University of Michigan, Horace H. Rackham School of Graduate Studies ; http://deepblue.lib.umich.edu/bitstream/2027.42/191102/2/7510206 ...
openaire   +2 more sources

Azabicyclo Compounds—XI. A study of the fragmentation processes of quinuc‐lidine and some of its derivatives

Organic Mass Spectrometry, 1972
AbstractThe mass spectra of quinuclidine, all the ring position deuterated analogues and some methyl homologues have been measured. Plausible mechanistic interpretations of principal fragment ions are discussed, in the case of quinuclidine, with the help of deuteration in all the ring positions.
J. Paleček, J. Mitera
openaire   +1 more source

Studies of 1-azabicyclo compounds

Chemistry of Heterocyclic Compounds, 1966
I. M. Skvortsov   +2 more
openaire   +1 more source

Azabicyclo compounds. VIII. Hofmann elimination of 3-methyl-1-azabicyclo[2,2,2]octane

Collection of Czechoslovak Chemical Communications, 1967
J. Paleček, Z. Polívka
openaire   +1 more source

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