Results 81 to 90 of about 4,192 (189)

The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.

, 2011
The discovery of a novel series of 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamide antagonists of the vasopressin V(1A) receptor is disclosed.
Bingham, Matilda, Kirsteen Buchanan, Cliona MacSweeney, Lee Fielding, Claxton, C, Presland, J, Mark Craighead, Brown, Angus, Fielding, L, Fiona Thomson, Hazel Sloan, Craighead, M, Buchanan, K, Irving, N, David Barn, Fielding, Lee, Goutcher, S, Gibson, L, Zara Turnbull, Milne, R, Sloan, H, Young, Trevor, Baker, James, Wishart, G, Goodwin, R, Baker, J, Presland, Jeremy, Barn, David, Goodwin, Richard, Sloan, Hazel, Wishart, Grant, Angus Brown, Arbuckle, William, Thomson, Fiona, Bingham, M, Susan Napier, Chris Claxton, Claxton, Chris, Brown, A, Irving, Nicholas, Milne, Rachel, Mort, Chris, Trevor Young, Barn, D, Napier, S, Chris Mort, Turnbull, Zara, Grant Wishart, Craighead, Mark, Nicholas Irving, James Baker, Byford, Alan, Arbuckle, W, Susan Goutcher, Rachel Milne, Buchanan, Kirsteen, Jeremy Presland, Lindsay Gibson, Alan Byford, Young, T, Mort, C, Thomson, F, William Arbuckle, MacSweeney, C, MacSweeney, Cliona, Turnbull, Z, Napier, Susan, Richard Goodwin, Byford, A, Goutcher, Susan, Gibson, Lindsay, Matilda Bingham   +71 more
core   +1 more source

3-oxo-3-thia-2-azabicyclo[2.2.1]hept-5-en-2-carboxylates: the first isolation and characterization

, 2012
Methyl and benzyl 3-oxo-3-thia-2-azabicyclo[2.2.1]hept-5-en-2-carboxylate were isolated at r.t. and characterized for the first time. Both endo and exo- isomers were observed. In suitable experimental conditions (stoichiometric amount of sodium acetate, –
Ponticelli, F., Guideri, L.
core   +1 more source

Synthesis and dopamine transporter binding affinities of 3α-Benzyl-8-(diarylmethoxyethyl)-8-azabicyclo[3.2.1]octanes

, 2002
A series of 3α-benzyl-8-(diarylmethoxyethyl)-8-azabicyclo[3.2.1]octanes was synthesized and the binding affinities of the compounds were determined at the dopamine transporter.
Zhu, Naijue, Klein-Stevens, Cheryl, Trudell, Mark L, Bradley, Amy L, Izenwasser, Sari, Wade, Dean   +5 more
core   +1 more source

Synthesis of dopamine transporter selective 3-diarylmethoxymethyl-8-arylalkyl-8-azabicyclo[3.2.1]octane derivatives

, 2006
A series of diarylmethoxymethyltropane-GBR hybrid analogues with all three possible stereochemical orientations at C3 were synthesized and evaluated at dopamine and serotonin transporters.
Zhang, Suhong, Xu, Liang, Trudell, Mark L, Izenwasser, Sari, Wade, Dean   +4 more
core   +1 more source

Synthesis of Azabicyclo[2.2.n]alkane Systems as Analogues of 3-[1-Methyl-2-(S)-pyrrolidinyl- methoxy]pyridine (A-84543)

, 2016
This work is connected with the epibatidine field and describes the synthesis of several analogues of compounds that present affinity for nicotinic acetylcholine receptors, such as 3-[1-methyl-2-(S)-pyrrolidinylmethoxy]pyridine (A-84543). These analogues
J. H. Busto (2496457), A. Avenoza (2496466), J. M. Peregrina (2496460), J. Carreras (2496463)   +3 more
core   +1 more source

Studies on 1-Azabicyclo Compounds. XXIII. Mercuric Acetate Oxidation of Deoxynupharidine

YAKUGAKU ZASSHI, 1975
YOSHIO ARATA, SHINGO YASUDA, RUMIKO FUJITA   +2 more
openaire   +2 more sources

Studies on 1-Azabicyclo Compounds. VI. : A Convenient Synthesis and Dehydrogenation of Octahydroquinolizine

YAKUGAKU ZASSHI, 1969
Y, Arata, T, Shioda, J, Yamada, Y, Hayashi   +3 more
openaire   +3 more sources

Studies on 1-azabicyclo compounds. XXII. Stereochemistry of 9a-substituted quinolizidine methiodides.

Chemical and Pharmaceutical Bulletin, 1975
ARATA, YOSHIO, AOKI, TADASHI, HANAOKA, MIYOJI, KAMEI, MICHIE   +3 more
openaire   +2 more sources

PdII-Mediated Oxidative Amination for Access to a 9-Azabicyclo[4.2.1]nonane Compound Library and Anatoxin-a

, 2018
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Intramolecular oxidative amination of readily accessible aminocyclooct-4-enes provides rapid and regioselective access to the 9-azabicyclo[4.2.1]nonane framework characteristic of the natural product anatoxin-a (1).
Dawood, Rafid S., Chidipudi, Suresh R., O'Connor, Daniel C., Lewis, William, Hamza, Daniel, Pearce, Christopher A., Jones, Geraint, Wilkie, Ross P., Georgiou, Irene, Storr, Thomas E., Moore, Jonathan C., Stockman, Robert A.   +11 more
openaire  

Studies on 1-Azabicyclo Compounds. (4). : Synthesis of 4-Substituted Octahydroisoquinolizines

YAKUGAKU ZASSHI, 1968
Y, Arata, K, Sakai, T, Asai, M, Tsukioka
openaire   +3 more sources