Results 61 to 70 of about 4,192 (189)
2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone serves as a versatile oxidant and redox catalyst for CC bond formation through hydride abstraction or single‐electron transfer. Stoichiometric and catalytic systems enable benzylic, allylic, and aromatic CH activation under mild, metal‐free conditions, providing sustainable routes to complex and bioactive ...
Dohoon Cha, Sun‐Joon Min
wiley +1 more source
Studies in Bicyclic Compounds [PDF]
Part I : Synthetic approaches to allohimachalol 2-(gamma-formylbutyl )-2,6,6-trimethylcycloheptanone was synthesised in six steps from tetrahydroeucarvone.
Wall, Richard Terence
core
Photochemical addition of acrylonitrile to 1,4-dihydropyridines 1 and 2 followed by catalytic hydrogenation of the products gave trans-8- and trans-7-cyano-cis-2-azabicyclo[4.2.0]octane-6-carboxylates 6a, b and 8a, b; the corresponding cis 7b, 9 and ...
Donati, Donato +3 more
core +1 more source
The new 2‐benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone (HL) and its copper(II), nickel(II), cobalt(III), and iron(III) coordination compounds [Cu(L)Cl] (1), [Cu(L)NO3] (2), {[Cu(L)(Cl2CHCOO)]}n (3), [Ni(HL)2](NO3)2 (4), [Fe(L)2]NO3 (5), [Co(L)2]NO3 (6) were obtained.
Ianina Graur +6 more
wiley +1 more source
Formation of 3-azabicyclo[3.3.1]non-3-enes: Imino amides vs. imino alkenes
An effective method for synthesising alkaloid-like compounds containing the 3-azabicyclo[3.3.1]non-3-ene core structure was successfully carried out in a stereoselective manner via the bridged-Ritter reactions.
Williams, SG +6 more
core +1 more source
A series of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one compounds was designed and synthesized as a new class of inhibitors for cysteine proteases cathepsins B, L, K, and S.
Kaleta, Jadwiga +6 more
core +1 more source
Synthesis and antiprotozoal activities of new 3-azabicyclo[3.2.2]nonanes
Some antimalarial agents in use typically bear basic side chains as ligands. Such ligands were attached to the amino substituent of a bridgehead atom of already antiprotozoal active 3-azabicyclo[3.2.2]nonanes.
Faist, Johanna +8 more
core +1 more source
Radical Retrosynthesis of Natural Products Enabled by Iron‐Based Reductive Olefin Coupling
This review highlights iron‐catalyzed reductive olefin coupling (ROC)—a strategy for C─C bond formation driven by metal‐hydride hydrogen atom transfer (MHAT)—as a key tool in natural products synthesis. This review surveys dozens of total syntheses employing ROC‐based strategies, highlighting its power to forge strained rings, quaternary centers, and ...
Griffin L. Barnes +2 more
wiley +1 more source
Synthesis of Analogues of Epibatidine based on the 2-azabicyclo[2.2.1]heptane system
Epibatidine (exo-2-(6-chloro-3-pyridyl)-7-azabicyclo[2.2.1]heptane) is an alkaloid isolated from the skin of the Ecuadorian poison frog. It has been known since 1992 and has high binding affinity for nicotinic acetylcholine receptors.
Huda Ismail Al-Rubaye (7773863)
core +1 more source
Reductive amido bond cleavage reaction, previously elaborated by our laboratory for the synthesis of carbocyclic ribothymidine from readily available 2-azabicyclo[2.2.1]hept-5-en-3-one, was successfully applied to the synthesis of carbocyclic analogues of thymidine and related compounds.
KATAGIRI, Nobuya +3 more
openaire +2 more sources

