Results 41 to 50 of about 4,192 (189)
Chemistry – A European Journal, EarlyView.Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato +3 more
wiley +1 more source
)‐2‐Substituted‐1‐azabicyclo[2.2.1]heptanes
, 2009 The first stereoselective synthesis of two diastereomeric 1-azabicyclo[2.2.1]heptanes substituted at the 2-position from an easily accessible (R)-2-substituted-4-piperidone is reported.
Ramón Badorrey +7 more
core +1 more source
An alkaloid-like 3-azabicyclo[3.3.1]non-3-ene library obtained from the bridged Ritter reaction [PDF]
, 2017 © 2016 Elsevier Ltd A small, diverse library of novel alkaloid-like compounds was synthesised using the bridged Ritter reaction with (−)-β-pinene and subsequent scaffold derivatisation. Structural diversity was achieved by varying the nitrile used in the
Williams, SG +3 more
core +1 more source
Anomeric Amides: Valuable Reagents in Synthetic Organic Chemistry
Angewandte Chemie, Volume 138, Issue 12, 16 March 2026.Enabling late‐stage transformations and skeletal editing, anomeric amides have recently emerged as powerful synthetic tools. Due to their unique properties, anomeric amides have been employed in reactions ranging from amination to halogenation. This minireview provides an overview of recent progress in using anomeric amides across a variety of ...
Arushi Garg +3 more
wiley +2 more sources
Investigations Into the Metabolism and Elimination of Tesofensine in Human Urine
Drug Testing and Analysis, EarlyView.This study investigated tesofensine metabolism and urinary elimination after a single 483 μg intake via a dietary supplement. In six volunteers, urine was collected up to 659 h. LC‐HRMS/MS identified four tentative metabolites; maximum urinary concentrations reached 4 ng/mL within 4–48 h.
O. Krug, A. Thomas, M. Thevis
wiley +1 more source
, 2010 The endo and exo isomers of (+/-)-methyl 2-hydroxy-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylates and the in situ-prepared endo and exo isomers of (+/-)-methyl 2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate were treated with diphenylphosphinic chloride ...
Carlos A D Sousa +7 more
core +1 more source
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
, 2016 The discovery of new highly potent and selective triple reuptake inhibitors is reported. The new classes of 1-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes are described together with detailed ...
Anna Checchia (2309827) +25 more
core +1 more source
Stereodivergent Access to Polyhydroxylated 10-Azabicyclo[4.3.1]decanes as New Calystegine Analogues
, 2016 A rapid and stereodivergent access to polyhydroxylated 10-azabicyclo[4.3.1]decanes as new calystegine analogues by way of a double benzotriazolyl/carbon nucleophile exchange followed by a ring-closing metathesis was achieved.
Olivier R. Martin (204927) +5 more
core +3 more sources
ChemistryEurope, Volume 4, Issue 6, June 2026.Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu +2 more
wiley +1 more source