Results 41 to 50 of about 3,736 (153)

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

Studies on 1-Azabicyclo Compounds. XVI. Synthesis of 1'-Methylindan-2-spiro-2'-piperazine and Related Compounds

Chemical and Pharmaceutical Bulletin, 1973
A new synthesis of the spirodiamines (IIIa-c) from the methiodides (Ia-c) via the spiroaminolactams (VIIa-c) by Stevens rearrangement is described.
KATO, HIDEO, KOSHINAKA, EIICHI, ARATA, YOSHIO, HANAOKA, MIYOJI   +3 more
openaire   +2 more sources

Organocatalytic enantioselective synthesis and derivatizations of bridged <i>N</i>,<i>O</i>-acetal bicyclic scaffolds. [PDF]

Chem Sci
Tan J, Yusuipujiang N, Zhang J, Jiang XY, Zhang Z, Wang Y, Ma D.   +6 more
europepmc   +1 more source

Switchable annulation paths to diverse N-bridged bicyclic scaffolds via ligand-directed dicarbonylation. [PDF]

Nat Commun
Liu YK, Yang P, Wang LC, Bao ZP, Wu XF.
europepmc   +1 more source

Cascade transformation of 2-(diazoacetyl)-2<i>H</i>-azirines to 2-aroyl-3-hydroxy-1<i>H</i>-pyrroles via condensation with aromatic aldehydes. [PDF]

Beilstein J Org Chem
Zanakhov TO, Galenko EE, Novikov MS, Khlebnikov AF.   +3 more
europepmc   +1 more source

Diastereoselective Cyclopropanation with Secondary Diazoacetamides to Access <i>endo</i>-Azabicyclo[3.1.0]hexane-6-carboxamides. [PDF]

Org Lett
Nguyen TH, Saito T, Chang W, Navarro A, Davies HML.   +4 more
europepmc   +1 more source

Studies on 1-Azabicyclo Compounds. VI. : A Convenient Synthesis and Dehydrogenation of Octahydroquinolizine

YAKUGAKU ZASSHI, 1969
Y, Arata, T, Shioda, J, Yamada, Y, Hayashi   +3 more
openaire   +3 more sources

Regio- and Stereoselective Deprotonation and Functionalization of Strained 1-Aza[n.1.0]bicycles. [PDF]

J Am Chem Soc
Xie T, Plowright T, Somper JD, Fairchild M, Soler J, Tyler JL, Duarte F, Aggarwal VK.   +7 more
europepmc   +1 more source

Studies on 1-Azabicyclo Compounds. (4). : Synthesis of 4-Substituted Octahydroisoquinolizines

YAKUGAKU ZASSHI, 1968
Y, Arata, K, Sakai, T, Asai, M, Tsukioka
openaire   +3 more sources