Perangustols A and B, a pair of new azaphilone epimers from a marine sediment-derived fungus Cladosporium perangustm FS62 [PDF]
, 2016 A pair of new azaphilone epimers, perangustols A-B (1–2), and two new natural products (3–4), together with two known metabolites (5–6) were isolated from the culture of the marine sediment-derived fungus Cladosporium perangustum FS62.
Zhang-Hua Sun (1541521) +5 more
core +1 more source
Characterization of a Silent Azaphilone Gene Cluster from Aspergillus niger ATCC 1015 Reveals a Hydroxylation-Mediated Pyran-Ring Formation [PDF]
, 2012 SummaryAzaphilones are a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities.
Zabala, Angelica O. +3 more
core +1 more source
Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by Azaphilones.
The Journal of Antibiotics, 1999 The effect of thirteen different fungal azaphilones, which have a common 6-iso-chromane-like ring, was tested on cholesteryl ester transfer protein (CETP) activity in vitro. Chaetoviridin B showed the most potent inhibitory activity with an IC50 value of < 6.2 microM, followed by sclerotiorin with an IC50 value of 19.4 microM. Rotiorin, chaetoviridin A
H, Tomoda +9 more
openaire +3 more sources
Thielavialides A–E, Nor-Spiro-azaphilones, and a Bis-spiro-azaphilone from Thielavia sp. PA0001, An Endophytic Fungus Isolated from Aeroponically Grown Physalis alkekengi [PDF]
, 2015 Four new nor-spiro-azaphilones, thielavialides A–D (1– 4), a new bis-spiro-azaphilone, thielavialide E (5), together with pestafolide A (6), were isolated from the endophytic fungal strain, Thielavia sp.
Raphael Gruener (1324611) +3 more
core +1 more source
A 90-day oral toxicity study evaluation of azaphilone derived from Talaromyces amestolkiae: A natural food colorant [PDF]
Colorants are widely used in the food industry, especially artificial ones, due to their practicality and low cost. However, some artificial colorants can be harmful to human health. In order to substitute the artificial sources, some microorganisms such
Alves, Mônica Rodrigues +8 more
core +1 more source
Pleiotropically activation of azaphilone biosynthesis by overexpressing a pathway-specific transcription factor in marine-derived Aspergillus terreus RA2905 [PDF]
The genome sequencing of Aspergillus terreus reveals that the vast number of predicted biosynthetic gene clusters have not reflected by the metabolic profile observed under conventional culture conditions.
Lv, Ling +10 more
core +1 more source
Journal of FungiMonascus, a genus of fungi known for its fermentation capability and production of bioactive compounds, such as Monascus azaphilone pigments and Monacolin K, have received considerable attention because of their potential in biotechnological applications.
Yunxia Gong +6 more
doaj +1 more source
Efficient Production of Natural Yellow Azaphilone Pigments from Monascus purpureus Regulated by Microparticle-Triggered Stress [PDF]
Interaction with inert substances can profoundly affect the biosynthesis of metabolites in microorganisms. Here, we show that SiO2 microparticles cause changes in the cell morphology of Monascus purpureus.
Hu, Wen Lin +7 more
core +1 more source
Talaromyces atroroseus:Genome sequencing, Monascus pigments and azaphilone gene cluster evolution [PDF]
, 2015 Monascus pigmenter har i Asien været brugt til farvning af fødevarer i århundreder. Industrielt producerede Monascus pigmenter er dog imidlertid ikke godkendt til brug i fødevarer i hverken EU eller USA.
Rasmussen, Kasper Bøwig
core
Elicitation-Induced Enhancement of Lovastatin and Pigment Production in Monascus purpureus C322
FermentationMonascus purpureus is a filamentous fungus renowned for producing bioactive secondary metabolites, including lovastatin and azaphilone pigments. Lovastatin is valued for its cholesterol-lowering properties and cardiovascular benefits, while Monascus ...
Sirisha Yerramalli +3 more
doaj +1 more source