Results 101 to 110 of about 976 (197)

Fungal polyketide azaphilone pigments as future natural food colorants?

, 2010
The recent approval of fungal carotenoids as food colorants by the European Union has strengthened the prospects for fungal cell factories for the production of polyketide pigments.
Sameer A.S. Mapari, Meyer, Anne S., Anne S. Meyer, Ulf Thrane, Mapari, Sameer Shamsuddin, Thrane, Ulf   +5 more
core   +1 more source

Semisynthetic diversification of the fungal azaphilone austdiol highlights scaffold-encoded reactivity in natural products

In this study, we leveraged access to a prolific fungal producer of the azaphilone austdiol to explore the chemical space around this important mycotoxin.
John A Kalaitzis, Daniel Vuong, Paul Mirzayans, Andrew M Piggott, Stefan Valter, Scott Minns, Ernest Lacey, Andrew Crombie   +7 more
core   +1 more source

Characterization of a Silent Azaphilone Gene Cluster from Aspergillus niger ATCC 1015 Reveals a Hydroxylation-Mediated Pyran-Ring Formation [PDF]

, 2012
SummaryAzaphilones are a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities.
Zabala, Angelica O., Chooi, Yit-Heng, Xu, Wei, Tang, Yi   +3 more
core   +1 more source

Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by Azaphilones.

The Journal of Antibiotics, 1999
The effect of thirteen different fungal azaphilones, which have a common 6-iso-chromane-like ring, was tested on cholesteryl ester transfer protein (CETP) activity in vitro. Chaetoviridin B showed the most potent inhibitory activity with an IC50 value of < 6.2 microM, followed by sclerotiorin with an IC50 value of 19.4 microM. Rotiorin, chaetoviridin A
H, Tomoda, C, Matsushima, N, Tabata, I, Namatame, H, Tanaka, M J, Bamberger, H, Arai, M, Fukazawa, K, Inoue, S, Omura   +9 more
openaire   +4 more sources

Supplemental material - Supplemental material for Screening of Azaphilone Derivatives From Monascus pilosus-Fermented Rice (Red Yeast Rice) and Their Evaluation as Nonsteroidal Androgen Receptor Antagonists

, 2019
Supplemental material, Supplemental material, for Screening of Azaphilone Derivatives From Monascus pilosus-Fermented Rice (Red Yeast Rice) and Their Evaluation as Nonsteroidal Androgen Receptor Antagonists by Ming-Der Wu, Ming-Jen Cheng, Yen-Lin Chen ...
Tai-Wei D. Liu (8135007), Kai-Ping Chen (6056111), Ming-Der Wu (317076), Ming-Jen Cheng (771104), Yen-Lin Chen (317075)   +4 more
core   +1 more source

From Random Perturbation to Precise Targeting: A Comprehensive Review of Methods for Studying Gene Function in Monascus Species

Journal of Fungi
Monascus, a genus of fungi known for its fermentation capability and production of bioactive compounds, such as Monascus azaphilone pigments and Monacolin K, have received considerable attention because of their potential in biotechnological applications.
Yunxia Gong, Shengfa Li, Deqing Zhao, Xi Yuan, Yin Zhou, Fusheng Chen, Yanchun Shao   +6 more
doaj   +1 more source

A new epimer of azaphilone derivative pinophilin B from the gorgonian-derived fungus Aspergillus fumigatus 14–27

, 2019
A new epimer of azaphilone derivative pinophilin B, epi-pinophilin B (1), and three known analogues (2–4) were obtained from the culture of the gorgonian-derived fungus Aspergillus fumigatus 14–27.
Xiao-Yue Peng (7443221), Chang-Yun Wang (542934), Ya-Hui Zhang (5408948), Hua-Jie Zhu (2020408), Fei Cao (650073), Li-Xi Feng (7443224)   +5 more
core   +1 more source

A new azaphilone from the entomopathogenic fungus Hypocrella sp.

, 2015
This report describes the isolation of a new azaphilone, designated hypocrellone A (2), together with five known compounds (1, 3–6) from a submerged culture of the entomopathogenic fungus Hypocrella sp. (isolate WYTY-21). The absolute stereostructures of
Xiangyun Zang (709815), Lindan Yao (709817), Qingfeng Guo (709814), Xiaoyun He (330575), Xiong Guan (423435), Liping Cao (547902), Lili Dong (597060), Junzhi Qiu (709818), Zijian Gu (709816)   +8 more
core   +1 more source

Nature and nurture:Confluence of pathway determinism with metabolic and chemical serendipity diversifies: Monascus azaphilone pigments

, 2019
Covering: up to June 2018 Understanding the biosynthetic mechanisms that generate the astounding structural complexity and variety of fungal secondary metabolites (FSMs) remains a challenge.
Chen, Fusheng, Feng, Yanli, Chen, Wanping, Molnár, István; id_orcid   +3 more
core   +1 more source

Talaromyces atroroseus:Genome sequencing, Monascus pigments and azaphilone gene cluster evolution [PDF]

, 2015
Monascus pigmenter har i Asien været brugt til farvning af fødevarer i århundreder. Industrielt producerede Monascus pigmenter er dog imidlertid ikke godkendt til brug i fødevarer i hverken EU eller USA.
Rasmussen, Kasper Bøwig
core