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Synthesis of Azaphilone-Based Chemical Libraries [PDF]

open access: yesACS Combinatorial Science, 2012
The synthesis of azaphilone scaffolds that have been further diversified by cross coupling acylation and amine addition is reported. Methodology development also led to novel modifications including C5 acetoxylation and condensations producing isoquinolin-6(7H) structures. Overall, the library synthesis afforded three azaphilone sublibraries, including
Mathieu Achard   +2 more
exaly   +4 more sources
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An azaphilone from Talaromyces tardifaciens

Phytochemistry, 1995
Abstract A new azaphilone derivative, monomethyl-(+)-mitorubrin, was isolated from the ascomata of Talaromyces tardifaciens . The structure was determined on the basis of spectroscopic investigations.
Shun-Ichi Udagawa   +2 more
exaly   +2 more sources

Azaphilone alkaloids: prospective source of natural food pigments

Applied Microbiology and Biotechnology, 2021
Azaphilone, biosynthesized by polyketide synthase, is a class of fungal metabolites. In this review, after brief introduction of the natural azaphilone diversity, we in detail discussed azaphilic addition reaction involving conversion of natural azaphilone into the corresponding azaphilone alkaloid.
Lujie Liu, Zhilong Wang, Wang Zhilong
exaly   +3 more sources

Derivates of azaphilone Monascus pigments

Biocatalysis and Agricultural Biotechnology, 2017
Progress Research on Monascus pigments has been very rapidly, includes the discovery of new pigments and methods used for the isolation and identification of new pigments. Currently, nearly fifty seven new pigments have been found which are derivatives of the six main pigments that already exist.
Anna Yuliana   +2 more
exaly   +4 more sources

Cytochalasans and azaphilones: suitable chemotaxonomic markers for the Chaetomium species

Applied Microbiology and Biotechnology, 2021
The accurate taxonomic concept of the fungal Chaetomium species has been a hard work due to morphological similarity. Chemotaxonomy based on secondary metabolites is a powerful tool for taxonomical purposes, which could be used as an auxiliary reference to solve the problems encountered in the classification of Chaetomium.
Meng-Yue Yang   +5 more
openaire   +2 more sources

Azaphilone pigments from a yellow mutant of the fungus Monascus kaoliang

Phytochemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Prasat Kittakoop   +2 more
exaly   +3 more sources

Azaphilones from the Endophyte Chaetomium globosum

Journal of Natural Products, 2011
Six new azaphilones, 5'-epichaetoviridin A (7), 4'-epichaetoviridin F (9), 12β-hydroxychaetoviridin C (10), and chaetoviridins G-I (11-13), and six known azaphilones, chaetoviridins A-E (1-5) and 4'-epichaetoviridin A (8), were isolated from the endophytic fungus Chaetomium globosum cultivated in PDB medium for 21 days.
Warley S, Borges   +5 more
openaire   +2 more sources

Bis-spiro-azaphilones and azaphilones from the fungi Chaetomium cochliodes VTh01 and C. cochliodes CTh05

Tetrahedron, 2008
Abstract Four new dimeric spiro-azaplilones, cochliodones A–D (1–4), two new azaphliones, chaetoviridines E and F (5 and 6), a new epi-chaetoviridin A (7), together with five known compounds, chaetoviridin A (8), ergosterol (9), chaetochalasin A (10), 24(R)-5α,8α-epidioxyergosta-6-22-diene-3β-ol (11), and ergosterol-β- d -glucoside (12) were isolated
Nutchanat Phonkerd   +5 more
openaire   +1 more source

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