Results 41 to 50 of about 912 (190)

Identification of azaphilone derivatives of Monascus colorants from Talaromyces amestolkiae and their halochromic properties [PDF]

, 2022
Currently, the ability to produce several kinds of water-soluble red natural colorants makes the genus Talaromyces particularly important to the dye industry, which can be an alternative to the use of harmful synthetic colorants.
de Oliveira, Fernanda, Gonzaga Dos Santos, André, Rocha, Inês L. D., Ventura, Sónia P. M., Gonzaga dos Santos, André [UNESP], Cláudia Gouveia Alves Pinto, Diana, José Crevelin, Eduardo, de Carvalho Santos Ebinuma, Valéria, Rocha, Inês L.D., de Carvalho Santos Ebinuma, Valéria [UNESP], de Oliveira, Fernanda [UNESP], Ventura, Sónia P.M.   +11 more
core   +1 more source

Segregation of the genus Parahypoxylon (Hypoxylaceae, Xylariales) from Hypoxylon by a polyphasic taxonomic approach [PDF]

MycoKeys, 2023
During a mycological survey of the Democratic Republic of the Congo, a fungal specimen that morphologically resembled the American species Hypoxylon papillatum was encountered.
Marjorie Cedeño-Sanchez, Esteban Charria-Girón, Christopher Lambert, J. Jennifer Luangsa-ard, Cony Decock, Raimo Franke, Mark Brönstrup, Marc Stadler   +7 more
doaj   +3 more sources

Application and stability of fungal pigments using jelly sweets as a food model system

International Journal of Food Science &Technology, Volume 58, Issue 12, Page 6761-6774, December 2023., 2023
A workflow depicting the stability study of fungal pigments in jelly‐sweet model system. Summary Natural pigments have seen an increase in usage over the past decades due to their acclaimed safety and active biological properties. This is in line with the shift in consumer market preferences requiring a source replacement for synthetic colourants ...
Tumisi Beiri Jeremiah Molelekoa, Laura Suzanne da Silva, Thierry Regnier, Wilma Augustyn   +3 more
wiley   +1 more source

Hybridorubrins A–D: Azaphilone Heterodimers from Stromata of Hypoxylon fragiforme and Insights into the Biosynthetic Machinery for Azaphilone Diversification

Chemistry – A European Journal, 2020
AbstractThe diversity of azaphilones in stromatal extracts of the fungus Hypoxylon fragiforme was investigated and linked to their biosynthetic machineries by using bioinformatics. Nineteen azaphilone‐type compounds were isolated and characterized by NMR spectroscopy and mass spectrometry, and their absolute stereoconfigurations were assigned by using ...
Kevin Becker, Sebastian Pfütze, Eric Kuhnert, Russell J. Cox, Marc Stadler, Frank Surup   +5 more
openaire   +3 more sources

Monasone Naphthoquinone Biosynthesis and Resistance in Monascus Fungi

mBio, 2020
Despite the important biological activities of natural product naphthoquinones, the biosynthetic pathways of and resistance mechanisms against such compounds remain poorly understood in fungi.
Mu Li, Lijing Kang, Xiaoli Ding, Jiao Liu, Qingpei Liu, Yanchun Shao, István Molnár, Fusheng Chen   +7 more
doaj   +1 more source

Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling

Medicinal Research Reviews, Volume 43, Issue 3, Page 614-682, May 2023., 2023
Abstract Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight cancer and overcome drug resistance in antitumor therapy. Understanding the molecular interactions and structural features of ferroptosis‐inducing compounds might ...
Solveigh C. Koeberle, Anna P. Kipp, Hermann Stuppner, Andreas Koeberle   +3 more
wiley   +1 more source

Synthesis of Azaphilone-Based Chemical Libraries [PDF]

, 2016
The synthesis of azaphilone scaffolds that have been further diversified by cross coupling acylation and amine addition is reported. Methodology development also led to novel modifications including C5 acetoxylation and condensations producing ...
Aaron B. Beeler (1317585), John A. Porco (1307085), Mathieu Achard (1588897)   +2 more
core   +1 more source

Asymmetric Syntheses of (−)-Mitorubrin and Related Azaphilone Natural Products [PDF]

, 2016
Asymmetric syntheses of (−)-mitorubrin and related azaphilone natural products are reported. Key steps involve copper-mediated, enantioselective oxidative dearomatization to prepare the azaphilone core and olefin cross-metathesis for side-chain ...
Jianglong Zhu (1528864), John A. Porco (1307085)   +1 more
core   +1 more source

Hybridorubrins A-D, novel azaphilone heterodimers from stromata of Hypoxylon fragiforme and insights into the biosynthetic machinery for azaphilone diversification. [PDF]

, 2020
The diversity of azaphilones in stromatal extracts of the fungus Hypoxylon fragiforme was investigated and linked to their biosynthetic machineries using bioinformatics.
Becker, Kevin, Stadler, Marc, Pfütze, Sebastian, Surup, Frank, Kuhnert, Eric, Cox, Russell   +5 more
core   +1 more source

Ancestral Sequence Reconstruction to Enable Biocatalytic Synthesis of Azaphilones. [PDF]

J Am Chem Soc
Biocatalysis can be powerful in organic synthesis but is often limited by enzymes' substrate scope and selectivity. Developing a biocatalytic step involves identifying an initial enzyme for the target reaction followed by optimization through rational design, directed evolution, or both.
Chiang CH, Wang Y, Hussain A, Brooks CL, Narayan ARH.   +4 more
europepmc   +3 more sources