Results 51 to 60 of about 912 (190)

Helicusin E, Isochromophilone X and Isochromophilone XI: New Chloroazaphilones Produced by the Fungus Bartalinia robillardoides Strain LF550

Marine Drugs, 2013
Microbial studies of the Mediterranean sponge Tethya aurantium led to the isolation of the fungus Bartalinia robillardoides strain LF550. The strain produced a number of secondary metabolites belonging to the chloroazaphilones.
Johannes F. Imhoff, Gerhard Bringmann, Torsten Bruhn, Arlette Erhard, Birgit Ohlendorf, Nils Jansen   +5 more
doaj   +1 more source

Orange, red, yellow: biosynthesis of azaphilone pigments in Monascus fungi [PDF]

, 2017
Each major step leading to the classical yellow, orange and red constituents of Monascus azaphilone pigments was defined.
He, Yi, Kun He, Mu Li, Molnár, István; id_orcid, Shao, Yanchun, Yuanyuan Lu, Xiaoxiao Guo, Li, Mu, Lijing Kang, Kang, Lijing, Runfa Chen, Xie, Nana, Yi He, Cox, Russell J., Chen, Runfa, Liu, Qingpei, Ding, Xiaoli, Youxiang Zhou, He, Kun, Nana Xie, Wanping Chen, Zhou, Youxiang, Chen, Fusheng, Lu, Yuanyuan, Fusheng Chen, Chen, Wanping, István Molnár, Molnár, Istvan, Qingpei Liu, Xiaoli Ding, Russell J. Cox, Yanchun Shao, Guo, Xiaoxiao   +32 more
core   +1 more source

Reengineering an Azaphilone Biosynthesis Pathway in Aspergillus nidulans To Create Lipoxygenase Inhibitors [PDF]

, 2016
Sclerotiorin, an azaphilone polyketide, is a bioactive natural product known to inhibit 15-lipoxygenase and many other biological targets. To readily access sclerotiorin and analogs, we developed a 2–3 step semisynthetic route to produce a variety of ...
Yi-Ming Chiang (1312392), Berl R. Oakley (183341), Clay C. C. Wang (313310), Amber D. Somoza (2112829), Kuan-Han Lee (313313)   +4 more
core   +1 more source

Multiformin-Type Azaphilones Prevent SARS-CoV-2 Binding to ACE2 Receptor

Cells, 2022
Protein microarray screenings identified fungal natural products from the azaphilone family as potent inhibitors of SARS-CoV-2 spike protein binding to host ACE2 receptors.
Linda Jansen-Olliges, Shambhabi Chatterjee, Lili Jia, Frank Stahl, Christian Bär, Marc Stadler, Frank Surup, Carsten Zeilinger   +7 more
doaj   +1 more source

Azaphilone Alkaloids with Anti-inflammatory Activity from Fungus Penicillium sclerotiorum cib-411 [PDF]

, 2019
Nine new azaphilone alkaloids, penazaphilones A–I (1–9), were isolated from the solid fermented rice culture of Penicillium sclerotiorum cib-411. The structures of compounds 1–9 were elucidated based on HRESIMS, NMR, and CD spectroscopic data.
Zong-Yuan Zhou (6336536), Lin-Wei Wu (1561873), Jia-Lin Tang (6336533), Guo-You Li (676444), Can Yao (6336539), Tao Yang (184280)   +5 more
core   +5 more sources

Genome mining of a fungal endophyte of Taxus yunnanensis (Chinese yew) leads to the discovery of a novel azaphilone polyketide, lijiquinone

Microbial Biotechnology, 2020
Summary Genome mining of Ascomycete sp. F53 (F53), a fungal endophyte of the traditional Chinese medicinal plant Taxus yunnanensis (Chinese yew), revealed 35 putative specialized metabolite biosynthesis gene clusters, one of which encodes a rarely seen ...
Jesse W. Cain, Kristin I. Miller, John A. Kalaitzis, Rocky Chau, Brett A. Neilan   +4 more
doaj   +1 more source

Hypoxia-Protective Azaphilone Adducts from Peyronellaea glomerata [PDF]

, 2018
Peyronellones A and B (1 and 2), a pair of rare tetracyclic caged adducts of azaphilone with pyruvic acid, along with four new analogues (3–6), were isolated from solid cultures of the endophytic fungus Peyronellaea glomerata.
Ming-Hua Yang (367114), Xiao-Bing Wang (1344267), Jian-Guang Luo (1344255), Tian-Xiao Li (801738), Rui-Huan Liu (1416466), Ling-Yi Kong (1344264), Jun Luo (120285)   +6 more
core   +3 more sources

A novel alkaloid serantrypinone and the spiro azaphilone daldinin D from Penicillium thymicola [PDF]

, 2001
The novel quinazoline metabolite serantrypinone (1) has been isolated from an isolate of the microfungus Penicillium thymicola together with daldinin D (2), a new peracetylated spiro azaphilone derivative.
Ariza, Marta Romero, Larsen, Thomas Ostenfeld, Petersen, Bent O., Christophersen, Carsten, Duus, Jens Øllgaard, Barrero, A.F.   +5 more
core   +1 more source

New Azaphilones from Nigrospora oryzae Co-Cultured with Beauveria bassiana

Molecules, 2018
In this study, the co-culture of Nigrospora oryzae and Beauveria bassiana, the endophytes in the seeds of Dendrobium officinale, were examined for metabolite diversity.
Zhuo-Xi Zhang, Xue-Qiong Yang, Qing-Yan Zhou, Bang-Yan Wang, Ming Hu, Ya-Bin Yang, Hao Zhou, Zhong-Tao Ding   +7 more
doaj   +1 more source

Pro-angiogenic New Chloro-Azaphilone Derivatives From the Hadal Trench-Derived Fungus Chaetomium globosum YP-106

Frontiers in Microbiology, 2022
Five new chloro-azaphilones, chaetofanixins A–E (1–5), and five known analogs (6–10) were isolated and identified from the hadal trench-derived fungus Chaetomium globosum YP-106.
Yaqin Fan, Chunjiao Jiang, Yan Zhang, Zhiheng Ma, Peihai Li, Lizhong Guo, Ting Feng, Liman Zhou, Lili Xu   +8 more
doaj   +1 more source