Results 81 to 90 of about 822 (147)

A microwave promoted and Lewis acid catalysed solventless approach to 4-azasteroids

Steroids, 2008
Romesh C Boruah
exaly   +2 more sources

Azasteroids from diosgenin: Synthesis and evaluation of their antiproliferative activity.

Steroids, 2020
In this work, we report the synthesis of two new azasteroids through the modification of the A and B rings of diosgenin 1. The 4-azasteroid derivative 12 was prepared in three steps using the α,β-insaturated-3-keto compound 11 as a precursor, which was ...
Anselmo A. Martínez-Gallegos, Gabriel Guerrero-Luna, Alejandra Ortiz-González, M. Cárdenas-García, S. Bernès, María Guadalupe Hernández-Linares   +5 more
semanticscholar   +1 more source

ChemInform Abstract: AZASTEROIDE 1. MITT. SYNTH. EINES AZASTEROID‐RINGSYST.

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractBeim Erhitzen von 2‐(1‐Cyclohexenyl)‐ähhylamin (I) mit dem Ester (II) am Rückfluß entsteht das Enaminlactam (III) (als Doppelbindungsisomerengemisch) in einer Ausbeute von 86%.
S. OHKI, M. AKIBA
openaire   +1 more source

Synthesis of 8‐Azasteroids

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
H. Surya Prakash Rao, S. P. Senthilkumar
openaire   +1 more source

Review on the Synthesis of 8-Azasteroids

Current Organic Chemistry, 2004
H. Senthilkumar
semanticscholar   +2 more sources

Effect of Azasteroids on Gram-Positive Bacteria

Journal of Bacteriology, 1967
A group of nitrogen-containing steroids closely related in structure was screened for antibacterial activity, by use of Bacillus subtilis and Sarcina lutea as the test organisms. The most active compounds were cholesterol derivatives containing a tertiary or quaternary nitrogen in, or ...
F, Varricchio, N J, Dorrenbos, A, Stevens   +2 more
openaire   +2 more sources

Azasteroids and heart adenosine triphosphatase

Biochemical Pharmacology, 1966
Abstract Azasteroids, some known to be active, others to be inactive as inotropic and antishock agents, were tested as inhibitors of a metal-stimulated heart ATPase. In every instance the biologically active azasteroids inhibited catalysis just as did ouabain and the erythrophleum alkaloids.
openaire   +2 more sources

Inhibition of mitochondrial respiration by progesterone and an azasteroid

Archives of Biochemistry and Biophysics, 1967
Abstract The effect of progesterone and 4-dimethylaminoethyl-4-aza-5-cholester-3-one methiodide (azasteroid) on DPNH and succinate oxidation in submitochondrial particles has been studied. Progesterone inhibited DPNH oxidation by oxygen or ubiquinone-6 equally.
F, Varricchio, D R, Sanadi
openaire   +2 more sources

The syntheses of 9-azasteroids—I

Tetrahedron, 1965
Abstract 4-Oxobenzo [c] quinolizidines have been examined as possible precursors of 9-azasteroids. 4-Oxo- and 3-methyl-4-oxobenzo [c] quinolizinium salts have been prepared and reduced to 4-hydroxy-benzo [c] quinolizidines, but attempts at oxidation of these alcohols have failed.
G. Jones, J. Wood
openaire   +1 more source

14-azasteroids via heterocycloaddition

Tetrahedron, 1978
Abstract Benzo[f]quinoline alcohol 1 has been converted into azasteroids 14 and 15 via a standard procedure and via application of the newly discovered 1.4 aryl radical rearrangement of α-halomethyl-N-arylsutfonylpiperidioes. An intramolecular accelerating effect of an OH group on LAH reductions of N-tosylamides is described.
R.P. Loven, W.N. Speckamp
openaire   +1 more source