Results 101 to 110 of about 615 (149)

ChemInform Abstract: AZASTEROIDE 1. MITT. SYNTH. EINES AZASTEROID‐RINGSYST.

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractBeim Erhitzen von 2‐(1‐Cyclohexenyl)‐ähhylamin (I) mit dem Ester (II) am Rückfluß entsteht das Enaminlactam (III) (als Doppelbindungsisomerengemisch) in einer Ausbeute von 86%.
S. OHKI, M. AKIBA
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N-Alkylation of 17-azasteroids

Steroids, 1994
N-Alkylation of 17-azasteroid lactams (16-oxo-17-azaandrost-5-en-3 beta-ol acetate 3 and its D-homo analog 4) was studied. It has been found that both lactams are readily alkylated with iodomethane or iodoethane. In contrast to this there was no reaction with 2-iodo-6-methylheptane due to the steric hindrance.
J W, Morzycki, Z, Lotowski
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Total Synthesis of 11‐Azasteroids.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Frédéric Cachoux, Malika Ibrahim-Ouali, Maurice Santelli   +2 more
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14-azasteroids via heterocycloaddition

Tetrahedron, 1978
Abstract Benzo[f]quinoline alcohol 1 has been converted into azasteroids 14 and 15 via a standard procedure and via application of the newly discovered 1.4 aryl radical rearrangement of α-halomethyl-N-arylsutfonylpiperidioes. An intramolecular accelerating effect of an OH group on LAH reductions of N-tosylamides is described.
R.P. Loven, W.N. Speckamp
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7-azasteroid analogues—I

Tetrahedron, 1973
Abstract Although 7-methoxy- and 6,7-dimethoxy-2-methyl-4-vinyl-isocarbostyrils could not be isolated and characterised, they have been generated in situ and shown to undergo cyclo-addition reactions with typical dienophiles. The enol acetate of 2-methyl-4-acetylisocarbostyril has also been trapped as its adduct with maleic anhydride and with p ...
S.F. Dyke, P.A. Bather, A.B. Garry, D.W. Wiggins   +3 more
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Synthesis of 8‐Azasteroids

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
H. Surya Prakash Rao, S. P. Senthilkumar
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Azasteroids and heart adenosine triphosphatase

Biochemical Pharmacology, 1966
Abstract Azasteroids, some known to be active, others to be inactive as inotropic and antishock agents, were tested as inhibitors of a metal-stimulated heart ATPase. In every instance the biologically active azasteroids inhibited catalysis just as did ouabain and the erythrophleum alkaloids.
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Azasteroids derived from fusidic acid

Journal of the Chemical Society, Perkin Transactions 1, 1998
The Beckmann rearrangement pathway of the (E)-11-oxime 6, derived from fusidic acid, one of the uncommon 9β-steroids with ring B constrained in a boat conformation, was investigated. It was found that 6 was converted into methyl 3-O-acetyl-11-aza-11a-homo-11a-oxo-24,25-dihydrofusidate 7, the ‘normal’ product of rearrangement, when treated with toluene ...
William S. Murphy, Basil Sarsam, George Ferguson, John F. Gallagher   +3 more
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Luminescence Properties of 8-azasteroid Molecules

Journal of Applied Spectroscopy, 1999
The chemical and biomedical studies of steroid heterocyclic analogs have arisen with the purpose of separation of unfavourable hormonal (influence on mineral and carbohydrate interchange) and valuable physiological (antiinflammatory, antishock, antiallergen action) effects intrinsic for steroids.
Afanasii A. Akhrem, Nikolai A. Borisevich, Olga V. Gulyakevich, Alexander L. Mikhalchuk, Sergei A. Tikhomirov, Georgii B. Tolstorozhev   +5 more
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Effect of Azasteroids on Gram-Positive Bacteria

Journal of Bacteriology, 1967
A group of nitrogen-containing steroids closely related in structure was screened for antibacterial activity, by use of Bacillus subtilis and Sarcina lutea as the test organisms. The most active compounds were cholesterol derivatives containing a tertiary or quaternary nitrogen in, or ...
F, Varricchio, N J, Dorrenbos, A, Stevens   +2 more
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