Results 91 to 100 of about 822 (147)

The synthesis of 9-azasteroids—II

Tetrahedron, 1965
Abstract The synthesis of 3-cyano-4-oxo-1,2,3,4,5,6-hexahydrobenzo[c]quinolizine (XIV), of 2-carbethoxy-3-oxo-1,2,3,4,5,6-hexahydrobenzo[c]quinolizine(XVII), and of 4-cyano-3-oxo-1,2,3,4,5,6-hexahydrobenzo[c]quinolizine (XXIX) is reported. Attempts to methylate 3-carbethoxy-4-oxo-1,2,3,4,5,6-hexahydrobenzo[c]quinolizine (II) were unsuccessful ...
G. Jones, J. Wood
openaire   +1 more source

7-azasteroid analogues—I

Tetrahedron, 1973
Abstract Although 7-methoxy- and 6,7-dimethoxy-2-methyl-4-vinyl-isocarbostyrils could not be isolated and characterised, they have been generated in situ and shown to undergo cyclo-addition reactions with typical dienophiles. The enol acetate of 2-methyl-4-acetylisocarbostyril has also been trapped as its adduct with maleic anhydride and with p ...
S.F. Dyke, P.A. Bather, A.B. Garry, D.W. Wiggins   +3 more
openaire   +1 more source

ChemInform Abstract: UEBER AZASTEROIDE

Chemischer Informationsdienst, 1972
AbstractDieser Übersichtsartikel beschreibt Synthesen und biologische Eigenschaften von Azasteroiden.
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A general synthesis of 6-azasteroids

2012
The ozonization of 7-ketocholesteryl acetate has yielded 5-keto-5, 7-seco-6-nor-3-cholesten-7-oic acid, an intermediate useful in the preparation of 6-azacholestane. Catalytic hydrogenation converted this intermediate to 5-keto-5,7-seco-6-norcholestan-7-oic acid which, upon treatment with benzyl amine, gave N-benzyl-6-aza-4-cholesten-7-one.
openaire   +1 more source

Targeting progesterone metabolism in breast cancer with l-proline derived new 14-azasteroids.

Bioorganic & Medicinal Chemistry, 2017
Jyotsana Singh, Ritesh Singh, Preeti Gupta, Smita Rai, Asha Ganesher, Preethi Badrinarayan, G. N. Sastry, R. Konwar, G. Panda   +8 more
semanticscholar   +1 more source

Azasteroids—VI

Tetrahedron, 1967
A.I. Meyers, J.C. Sircar
openaire   +1 more source

3D-QSAR studies on unsaturated 4-azasteroids as human 5alpha-reductase inhibitors: a self organizing molecular field analysis approach.

European journal of medicinal chemistry, 2010
S. Aggarwal, Suresh Thareja, T. Bhardwaj, Manoj Kumar   +3 more
semanticscholar   +1 more source

L-Proline derived nitrogenous steroidal systems: an asymmetric approach to 14-azasteroids

, 2013
Ritesh Singh, G. Panda
semanticscholar   +1 more source

Azasteroids as inhibitors of rat prostatic 5 alpha-reductase.

Journal of Medicinal Chemistry, 1984
G. H. Rasmusson, G. F. Reynolds, T. Utne, R. Jobson, R. Primka, C. Berman, J. R. Brooks   +6 more
semanticscholar   +1 more source

Cytotoxicity of 17a-Azasteroids towards liver and neuroblastoma cancer cell lines

, 2014
Neelima Dhingra, T. Bhardwaj
semanticscholar   +1 more source