Results 1 to 10 of about 133,046 (390)
Azathioprine in Rheumatoid Arthritis [PDF]
BMJ, 1969 The ability of azathioprine to reduce the corticosteroid requirements of patients with severe rheumatoid arthritis was tested under double-blind conditions against placebo. After 12 months a significant mean dose reduction of 36% was achieved without undue side-effects.
Matthew Mason +5 more
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Proactive pharmacogenomics in azathioprine-treated pediatric inflammatory bowel disease at a Chinese tertiary hospital [PDF]
Frontiers in PharmacologyBackgroundDespite the emergence of numerous innovative targeted therapies for the management of pediatric inflammatory bowel disease (IBD), azathioprine continues to be a pivotal first-line therapeutic agent.
Cai-Yun Long, Ying Huang
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Azathioprine versus beta interferons for relapsing-remitting multiple sclerosis: a multicentre randomized non-inferiority trial. [PDF]
PLoS ONE, 2014 For almost three decades in many countries azathioprine has been used to treat relapsing-remitting multiple sclerosis. However its efficacy was usually considered marginal and following approval of β interferons for this indication it was no longer ...
Luca Massacesi +10 more
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Perspectives in clinical research on Azathioprine for steroid-dependent ulcerative colitis [PDF]
Frontiers in MedicineThis study explores the application of Azathioprine in the treatment of ulcerative colitis (UC) and the challenges associated with its long-term use. While short-term studies demonstrate the efficacy of Azathioprine in steroid-dependent UC, long-term ...
Yuan-Ting Qu +4 more
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Azathioprine in Psoriasis [PDF]
Proceedings of the Royal Society of Medicine, 1973 D.D. MUNRO
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A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy [PDF]
Childhood Kidney Diseases, 2017 Azathioprine is commonly used as immunosuppressive therapy for various inflammatory diseases including chronic glomerulonephritis. Myelosuppression is a common side effect of azathioprine, resulting in the need for dose reduction.
Jae Choon Kim +6 more
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Sensing Methods of Immunosuppressant Drugs: Calcineurin Inhibitors and Purine Synthesis Inhibitor Agents [PDF]
ImmunoAnalysis, 2021 Today, immunosuppression is associated as a necessary protocol in renal posttransplantation follow-up to improve both patient and graft survival rates.
Zahra Golsanamlou +2 more
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Journal of Nepal Medical Association, 2016 Introduction: Immune thrombocytopenic purpura remains common blood disease in Nepal. Azathioprine is an oral immunosupressive medicine which has been used widely in various autoimmune disease and solid organ transplant patients. It is inexpensive, easily
Bishesh Sharma Poudyal +5 more
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Use of thiopurines in inflammatory bowel disease: an update [PDF]
Intestinal Research, 2022 Inflammatory bowel disease (IBD), once considered a disease of the Western hemisphere, has emerged as a global disease. As the disease prevalence is on a steady rise, management of IBD has come under the spotlight.
Arshdeep Singh +25 more
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Clinical and Translational Science, 2022 TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could also contribute to azathioprine myelotoxicity.
Laura L. Daniel +17 more
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