Results 1 to 10 of about 63,671 (294)
Proactive pharmacogenomics in azathioprine-treated pediatric inflammatory bowel disease at a Chinese tertiary hospital. [PDF]
Front PharmacolBackgroundDespite the emergence of numerous innovative targeted therapies for the management of pediatric inflammatory bowel disease (IBD), azathioprine continues to be a pivotal first-line therapeutic agent.
Long CY, Huang Y.
europepmc +2 more sources
A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy [PDF]
Childhood Kidney Diseases, 2017 Azathioprine is commonly used as immunosuppressive therapy for various inflammatory diseases including chronic glomerulonephritis. Myelosuppression is a common side effect of azathioprine, resulting in the need for dose reduction.
Jae Choon Kim +6 more
doaj +1 more source
Azathioprine versus beta interferons for relapsing-remitting multiple sclerosis: a multicentre randomized non-inferiority trial. [PDF]
PLoS ONE, 2014 For almost three decades in many countries azathioprine has been used to treat relapsing-remitting multiple sclerosis. However its efficacy was usually considered marginal and following approval of β interferons for this indication it was no longer ...
Luca Massacesi +10 more
doaj +1 more source
Use of thiopurines in inflammatory bowel disease: an update [PDF]
Intestinal Research, 2022 Inflammatory bowel disease (IBD), once considered a disease of the Western hemisphere, has emerged as a global disease. As the disease prevalence is on a steady rise, management of IBD has come under the spotlight.
Arshdeep Singh +25 more
doaj +1 more source
Journal of Nepal Medical Association, 2016 Introduction: Immune thrombocytopenic purpura remains common blood disease in Nepal. Azathioprine is an oral immunosupressive medicine which has been used widely in various autoimmune disease and solid organ transplant patients. It is inexpensive, easily
Bishesh Sharma Poudyal +5 more
doaj +3 more sources
Clinical and Translational Science, 2022 TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could also contribute to azathioprine myelotoxicity.
Laura L. Daniel +17 more
doaj +1 more source
Efficacy and Safety of Rituximab in Immunobullous Diseases: A Retrospective Study from a Tertiary Care Centre of Nepal [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: Rituximab is effective and safe treatment of immunobullous disorders. There are variations in doses of drugs used in different studies and uncertainties on when to use it along with use of adjuvant therapies. Efficacy and safety of this
Sudip Parajuli +3 more
doaj +1 more source
Bioscience Journal, 2021 This study was performed to evaluate the effectiveness of Echinacea purpurea (E.P.) on azathioprine (AZA)-induced immune deficiency in albino rats. Thirty six male albino rats were divided into six equal groups.
Emad Mohamed El-Sherbiny +2 more
doaj +1 more source
DCcov: Repositioning of Drugs and Drug Combinations for SARS-CoV-2 Infected Lung through Constraint-Based Modelling [PDF]
, 2021 The 2019 coronavirus disease (COVID-19) became a worldwide pandemic with currently no effective antiviral drug except treatments for symptomatic therapy. Flux balance analysis is an efficient method to analyze metabolic networks. It allows optimizing for a metabolic function and thus e.g., predicting the growth rate of a specific cell or the production
arxiv +1 more source
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis [PDF]
Anais Brasileiros de Dermatologia, 2015 We report the case of a 42-year-old female with a 5-year history of rheumatoid arthritis treated with Rituximab and Azathioprine. Three months after the initiation of Azathioprine, the patient started with dry cough and noted the rapid development of ...
Cristian Vera Kellet +3 more
doaj +2 more sources