Results 11 to 20 of about 133,046 (390)

Rituximab versus azathioprine for maintenance of remission for patients with ANCA-associated vasculitis and relapsing disease: an international randomised controlled trial

Annals of the Rheumatic Diseases, 2023
Objective Following induction of remission with rituximab in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) relapse rates are high, especially in patients with history of relapse.
Rona M. Smith, R. Jones, U. Specks, S. Bond, M. Nodale, R. Al-jayyousi, J. Andrews, A. Bruchfeld, B. Camilleri, S. Carette, C. Cheung, V. Derebail, T. Doulton, A. Ferraro, Lindsy J. Forbess, S. Fujimoto, S. Furuta, Ora Gewurz-Singer, L. Harper, T. Ito-Ihara, N. Khalidi, R. Klocke, C. Koening, Y. Komagata, C. Langford, P. Lanyon, R. Luqmani, Carol A. McAlear, L. Moreland, Kim Mynard, P. Nachman, C. Pagnoux, C. Peh, C. Pusey, D. Ranganathan, Rennie L. Rhee, R. Spiera, A. Sreih, Vladamir Tesar, G. Walters, C. Wroe, D. Jayne, P. Merkel   +42 more
semanticscholar   +1 more source

Leflunomide versus azathioprine for maintenance therapy of lupus nephritis: a prospective, multicentre, randomised trial and long-term follow-up

Annals of the Rheumatic Diseases, 2022
Objectives Previous studies have compared mycophenolate mofetil and azathioprine as maintenance therapy for lupus nephritis (LN). Leflunomide is an immunosuppressant widely used in the treatment of rheumatoid arthritis.
Q. Fu, Chunmei Wu, M. Dai, Suli Wang, Jian-hua Xu, L. Dai, Zhijun Li, Lan He, Xiaochun Zhu, Lingyun Sun, Liangjing Lu, C. Bao   +11 more
semanticscholar   +1 more source

Ustekinumab is more effective than azathioprine to prevent endoscopic postoperative recurrence in Crohn's disease

United European Gastroenterology journal, 2021
Background Preventing postoperative recurrence (POR) is a major concern in Crohn's disease (CD). While azathioprine is an option, no data is available on ustekinumab efficacy in this situation.
A. Buisson, S. Nancey, L. Manlay, D. Rubin, X. Hébuterne, B. Pariente, M. Fumery, D. Laharie, X. Roblin, G. Bommelaer, B. Pereira, L. Peyrin-Biroulet, L. Vuitton   +12 more
semanticscholar   +1 more source

Infection risk in sarcoidosis patients treated with methotrexate compared to azathioprine: A retrospective ‘target trial’ emulated with Swedish real‐world data

Respirology (Carlton South. Print), 2021
No clinical trial has examined the risk of infection associated methotrexate and azathioprine, two advocated treatments for sarcoidosis. We aimed to compare the 6‐month risk of infection after the initiation of methotrexate or azathioprine.
M. Rossides, S. Kullberg, D. di Giuseppe, A. Eklund, J. Grunewald, J. Askling, E. Arkema   +6 more
semanticscholar   +1 more source

Optical Coherence Tomography Reveals Longitudinal Changes in Retinal Damage Under Different Treatments for Neuromyelitis Optica Spectrum Disorder

Frontiers in Neurology, 2021
Background: Progressive retinal neuroaxonal damage after acute optic neuritis may occur in neuromyelitis optica spectrum disorder (NMOSD). However, it is unclear if treatments used to prevent attacks influence neurodegeneration.Objectives: We aimed to ...
Pei Zeng, Chen Du, Rui Zhang, Dongmei Jia, Feng Jiang, Moli Fan, Chao Zhang   +6 more
doaj   +1 more source

Efficacy and Safety of Rituximab in Immunobullous Diseases: A Retrospective Study from a Tertiary Care Centre of Nepal [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Rituximab is effective and safe treatment of immunobullous disorders. There are variations in doses of drugs used in different studies and uncertainties on when to use it along with use of adjuvant therapies. Efficacy and safety of this
Sudip Parajuli, Jyoti Vidhan, Dinesh Binod Pokhrel, Upama Paudel   +3 more
doaj   +1 more source

Azathioprine for multiple sclerosis [PDF]

Cochrane Database of Systematic Reviews, 2007
Azathioprine (AZA) is an immunosuppressive drug widely prescribed for the treatment of multiple sclerosis (MS) until the first half of the 1990s. It could be an alternative to interferon beta because it is less expensive. Concerns about its safety, mainly a possible increased risk of malignancy, have been raised.
CASETTA, Ilaria, Iuliano G, Filippini G.
openaire   +6 more sources

Association Between Genetic Polymorphisms of Metabolic Enzymes and Azathioprine-Induced Myelosuppression in 1,419 Chinese Patients: A Retrospective Study

Frontiers in Pharmacology, 2021
The aim of this study was to investigate the correlation between genetic polymorphisms of azathioprine-metabolizing enzymes and adverse reactions of myelosuppression. To this end, a retrospective analysis was performed on 1,419 Chinese patients involving
Zhao-Yang Chen, Yang-Hui Zhu, Ling-Yan Zhou, Wei-Qiao Shi, Zhou Qin, Bin Wu, Yu Yan, Yu-Wen Pei, Ning-Ning Chao, Rui Zhang, Mi-Ye Wang, Ze-Hao Su, Xiao-Jun Lu, Zhi-Yao He, Zhi-Yao He, Ting Xu, Ting Xu   +16 more
doaj   +1 more source

Azathioprine Hypersensitivity Syndrome during Treatment of Severe Interstitial Lung Disease with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Case Reports in Pulmonology, 2020
Azathioprine is used to treat anti-neutrophil cytoplasmic antibody- (ANCA-) associated vasculitis. Azathioprine hypersensitivity syndrome is often missed.
Eri Nakano, Tomohiko Asakawa, Mea Asou, Eri Nohara, Tomoyuki Seki, Makoto Araki   +5 more
doaj   +1 more source

Effectiveness of Echinacea purpurea extract on immune deficiency induced by azathioprine in male albino rats

Bioscience Journal, 2021
This study was performed to evaluate the effectiveness of Echinacea purpurea (E.P.) on azathioprine (AZA)-induced immune deficiency in albino rats. Thirty six male albino rats were divided into six equal groups.
Emad Mohamed El-Sherbiny, Hala Fawzy Osman, Mervat Sayed Taha   +2 more
doaj   +1 more source