Results 21 to 30 of about 66,048 (291)
Thoracic Cancer, 2023 An 82‐year‐old man was treated with ipilimumab and nivolumab for malignant pleural mesothelioma. Although he was previously treated with prednisolone (1 mg/kg/day) for immune‐related adverse event (irAE) hepatitis by a previous doctor, he still had ...
Keita Kawakado +9 more
doaj +1 more source
Increased Risk of Liver Cirrhosis during Azathioprine Therapy for Crohn’s Disease
Case Reports in Gastrointestinal Medicine, 2020 Azathioprine is a cornerstone of the therapy of Crohn’s disease. Unfortunately, infections and malignancies are relatively common adverse effects related to this drug; however, cirrhosis is exceptionally reported as a side effect. We report the case of a
Jenny Roselli +9 more
doaj +1 more source
Azathioprine favourably influences the course of malaria
Malaria Journal, 2009 Background Azathioprine triggers suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and exposure of phosphatidylserine at the erythrocyte surface. Eryptosis may accelerate the clearance of Plasmodium-infected erythrocytes.
Huber Stephan M +5 more
doaj +1 more source
Pharmaceuticals, 2023 Background: Crohn’s disease with upper gastrointestinal tract involvement occurs more often in children than adults and has the potential to interfere with oral drug absorption. We aimed to compare disease outcomes in children receiving oral azathioprine
Rebecca Casini +7 more
doaj +1 more source
Postgraduate Medical Journal, 1986 Summary Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and ...
openaire +2 more sources
Important problems in the diagnosis and treatment of autoimmune hepatitis (based on the Russian consensus 2017) [PDF]
Терапевтический архив, 2018 The analysis of publications devoted to the Russian Consensus on the Diagnostic and Treatment of Autoimmune Hepatitis (AIH), which was considered at the 43rd annual Scientific Session of the CNIIG From Traditions to Innovation (March 4, 2017) is carried ...
E V Vinnitskaya +12 more
doaj +1 more source
How Deep Learning in Antiviral Molecular Profiling Identified Anti-SARS-CoV-2 Inhibitors
Biomedicines, 2023 The integration of artificial intelligence (AI) into drug discovery has markedly advanced the search for effective therapeutics. In our study, we employed a comprehensive computational–experimental approach to identify potential anti-SARS-CoV-2 compounds.
Mohammed Ali +8 more
doaj +1 more source
The oncogenicity of azathioprine? [PDF]
Hepatology, 1988 One hundred and fifty-four patients with histologically verified non-alcoholic chronic liver disease were randomized to azathioprine or prednisone treatment. After a median of 91 months observation time, the cause of death was assessed retrospectively. Autopsy was performed in 82% of 71 deaths.
openaire +3 more sources
Treatment of Psoriasis with Azathioprine [PDF]
BMJ, 1974 Azathioprine treatment benefited 19 (66%) out of 29 patients suffering from severe psoriasis. Haematological complications were not troublesome and results of biochemical liver function tests remained normal. Minimal cholestasis was seen in two cases and portal fibrosis of a reversible degree in eight.
Dowling D. Munro +2 more
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BMC Infectious Diseases, 2019 Background Symptomatic primary Epstein-Barr virus infection is a usually self-limiting illness in adolescents. We present a case of an adolescent who had been receiving azathioprine for inflammatory bowel disease for four years and developed a life ...
Minna Honkila +8 more
doaj +1 more source