Results 41 to 50 of about 63,671 (294)

Immunoglobulin G4-Hepatopathy with Acute Hepatitis-Like Onset and Marked Centrilobular Necrosis: Clinicopathologically Unique Pattern of Hepatic Injury Related to Immunoglobulin G4-Related Disease

Case Reports in Gastroenterology, 2021
A 69-year-old man presented with jaundice and appetite loss. Blood analyses showed elevated aminotransferase levels, hyperbilirubinemia, positivity for antinuclear antibody, elevated immunoglobulin (Ig) G4 levels, and negativity for hepatitis virus ...
Kaori Mukai, Tsutomu Nishida, Shiro Adachi, Kengo Matsumoto, Naoto Osugi, Aya Sugimoto, Dai Nakamatsu, Masashi Yamamoto, Koji Fukui, Hiromi Tamura, Masami Inada   +10 more
doaj   +1 more source

Azathioprine-Induced Acute Submandibular Sialadenitis in a Crohn’s Disease Patient

GE: Portuguese Journal of Gastroenterology, 2020
Introduction: Azathioprine (AZA) is a widely used immunosuppressive drug in inflammatory bowel disease (IBD). The occurrence of adverse effects (AEs) is a major downside in the use of this drug, leading to treatment withdrawal in a variable proportion of
Joana Inês Alves da Silva, Cidalina Caetano, Isabel Pedroto   +2 more
doaj   +1 more source

Treatment of Psoriasis with Azathioprine [PDF]

BMJ, 1974
Azathioprine treatment benefited 19 (66%) out of 29 patients suffering from severe psoriasis. Haematological complications were not troublesome and results of biochemical liver function tests remained normal. Minimal cholestasis was seen in two cases and portal fibrosis of a reversible degree in eight.
Dowling D. Munro, Julian Verbov, Anthony du Vivier   +2 more
openaire   +3 more sources

Immunosuppressive Drugs in Early Systemic Sclerosis and Prevention of Damage Accrual

Arthritis Care &Research, EarlyView.
Objective Organ damage in patients with systemic sclerosis (SSc) in individual organs such as the lungs may be prevented by receiving immunosuppressive drugs (ISs). A new measure of global organ damage, the Scleroderma Clinical Trials Consortium Damage Index (SCTC‐DI), has allowed us to investigate whether receiving ISs may reduce global organ damage ...
Murray Baron, Mandana Nikpour, Dylan Hansen, Susanna Proudman, Wendy Stevens, on behalf of the Australian Scleroderma Interest Group and the Canadian Scleroderma Research Group, Joanne Sahhar, Nava Ferdowsi, Kathleen Morrisroe, Laura Ross, Gene Siew Ngian, Jennifer Walker, Janet Roddy, Lauren Host, Mohammed Osman, Peter Docherty, Paul Fortin, Marvin Jacob Fritzler, Genevieve Gyger, Alena Ikic, Niall Jones, Elzbieta Kaminska, Maggie Larche, Sophie Ligier, Ada Man, Ariel Masetto, Janet Pope, David Robinson, Tatiana Sofia Rodriguez‐Reyna, Mianbo Wang   +29 more
wiley   +1 more source

Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney transplant recipients

Turkish Journal of Internal Medicine, 2019
Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation.
Mehmet Usta, Yavuz Ayar, Alparslan Ersoy
doaj   +1 more source

Case report: NUDT15 polymorphism and severe azathioprine-induced myelosuppression in a young Chinese female with systematic lupus erythematosus: a case analysis and literature review

Frontiers in Pharmacology, 2023
Azathioprine is clinically used as an immunosuppressant for treating autoimmune diseases. However it has narrow therapeutic indices due to frequent myelosuppression.
Juan Gu, Yupei Lin, Yuhe Wang
doaj   +1 more source

Diverse Treatment Goals in Psoriatic Arthritis: Insights from participants in the PARC cohort

Arthritis Care &Research, Accepted Article.
Objective The aim was to examine patient‐reported treatment goals among individuals with psoriatic arthritis (PsA). Methods Participants in the Psoriatic Arthritis Research Consortium (PARC) completed standardized assessments including patient‐reported outcome (PROs) instruments between 2017‐2020.
Astia Allenzara, Kat Bush, M. Elaine Husni, Soumya M. Reddy, Jose U. Scher, Ethan Craig, Joelle Koplin, Jessica A. Walsh, Alexis Ogdie   +8 more
wiley   +1 more source

Severe distributive shock, neutrophilic dermatosis, and ST-elevation myocardial infarction in the setting of azathioprine hypersensitivity syndrome

Allergy, Asthma & Clinical Immunology
Background Azathioprine is a purine synthesis inhibitor used as an immunosuppressive therapy for many immune-mediated diseases. Azathioprine hypersensitivity reaction is a rare, life-threatening adverse reaction characterized by a range of multisystem ...
Samuel Su, Yu Ming Wang, Karver Zaborniak, Sate Hamza, Davinder S. Jassal, Marcus Blouw   +5 more
doaj   +1 more source

Acute-onset Alopecia in a Child: A Surrogate Marker of Azathioprine-induced Myelotoxicity

Indian Journal of Paediatric Dermatology, 2023
Azathioprine (AZA) is a widely used immunosuppressive which when not monitored cautiously can lead to life-threatening complications like myelotoxicity. In resource-limited countries, acute hair loss starting as early as 2 weeks after drug initiation can
Vibhu Mendiratta, Akanksha Agarwal, Smita Singh   +2 more
doaj   +1 more source

Detection of Hypoxanthine from Inosine and Unusual Hydrolysis of Immunosuppressive Drug Azathioprine through the Formation of a Diruthenium(III) System

Biosensors, 2021
Hypoxanthine (hpx) is an important molecule for both biochemistry research and biomedical applications. It is involved in several biological processes associated to energy and purine metabolism and has been proposed as a biomarker for a variety of ...
Marta Orts-Arroyo, Isabel Castro, José Martínez-Lillo   +2 more
doaj   +1 more source