Results 81 to 90 of about 63,671 (294)

DEVELOPMENT OF AZATHIOPRINE-BASED TREATMENT REGIMEN FOR PATIENTS WITH STEROID RESISTANT PEMPHIGUS BASED ON ASSESSMENT OF MOLECULAR MECHANISMS AT THE POST-RECEPTOR LEVEL

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Autoimmune pemphigus is the most severe skin and mucous membranes disorders with production of IgG autoantibodies to desmogleins 1 and 3. Administration of systemic corticosteroids may help to abrogate active signs of pemphigus. However, some
O. Yu. Olisova, N. L. Shimanovskiy, A. S. Dukhanin, N. P. Teplyuk, A. A. Lepekhova   +4 more
doaj   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

The use of steroids in adult epilepsy: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective The objective of this study is to systematically review the clinical studies investigating the use of steroids in adult epilepsy. Methods This systematic review utilized Preferred Reporting Items for Systematic Review and Meta‐analysis Protocols (PRISMA‐P) to examine literature on the use of steroids in adult epilepsy.
Ruth Walsh, Colin P. Doherty, Elisabeth Doran   +2 more
wiley   +1 more source

Three cases of atypical Rasmussen's encephalitis with delayed‐onset seizures

Epilepsia Open, EarlyView.
Abstract We retrospectively analyzed the clinical characteristics of three ARE cases with delayed‐onset seizures treated at Peking University First Hospital and Sanbo Brain Hospital from May 2021 to January 2023. We also reviewed previously reported atypical cases of Rasmussen's encephalitis (RE) in the literature, summarizing onset symptoms, seizure ...
Hongru Guo, Pan Gong, Guojing Yu, Chongyang Tang, Guoming Luan, Qingzhu Liu, Lixin Cai, Taoyun Ji   +7 more
wiley   +1 more source

Autoantibodies to intracellular “rods and rings” structures in two patients with autoimmune hepatitis treated with azathioprine

Autoimmunity, 2020
In vitro, inhibition of the synthesis of guanosine monophosphate (GMP) by various drugs such as ribavirin, acyclovir, azathioprine, and mycophenolic acid leads to the formation of subcellular structures in cultured cells.
Johanna Galaski, Anja C. Koop, Marc Lütgehetmann, Ansgar W. Lohse, Christina Weiler-Normann   +4 more
doaj   +1 more source

Lymphoma and azathioprine [PDF]

Arthritis & Rheumatism, 1972
David L. Kaplan, Ezra Sharon, James S. Paolino   +2 more
openaire   +3 more sources

Severe relapse after cessation of immunosuppressive therapy in a patient with co‐occurrence of neuromyelitis optica spectrum disorder and Sjögren's syndrome: A case report

Ibrain, EarlyView.
We report a girl with a diagnosis of “neuromyelitis optica spectrum disorder comorbid Sjogren's syndrome” whose condition showed significant improvement after treatment with corticosteroids and immunosuppressive drugs (prednisolone, hydroxychloroquine, and mycophenolate mofetil).
Man‐Min Zhu, Zu‐Cai Xu, Chang‐Yin Yu, Hao Huang   +3 more
wiley   +1 more source

Anti‐MDA5 and anti‐SSA/Ro52 antibodies double‐positive dermatomyositis overlapping with rheumatoid arthritis‐associated interstitial lung disease: A case report

International Journal of Rheumatic Diseases, Volume 25, Issue 12, Page 1437-1440, December 2022., 2022
Abstract Dermatomyositis (DM) is a poorly prognostic autoimmune disease the pathogenesis of which is multifactorial and not clearly defined. DM may be influenced by genes, environment, and immunity. The typical manifestations of DM are Gottron rash, heliotrope rash, rash on the shoulders and buttocks, erythema around fingernails, excessive keratosis of
Hong Xiong, QianRen Tan, Feng Luo, XueMei Yuan, Wukai Ma, XueMing Yao   +5 more
wiley   +1 more source

IgG4‐related constrictive pericarditis with previous asbestos exposure: A case report and literature review

ESC Heart Failure, EarlyView.
Ryohei Ono, Hiroki Kohno, Chihiro Ito, Kaoruko Aoki, Hirotoshi Kato, Togo Iwahana, Sakurako Harada‐Kagitani, Jun‐Ichiro Ikeda, Yoshio Kobayashi   +8 more
wiley   +1 more source