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Cosmeceutical Aptitudes of Azelaic Acid
Current Drug Research Reviews, 2021Azelaic acid (AZA) is a white crystalline dicarboxylic acid naturally found in grains, rye, and barley. AZA has substantial biological and therapeutic abilities (viz a viz) its anti-inflammatory, anti-oxidant, anti-keratinizing, anti-microbial properties, etc., which contribute to its applicability in the management of mild to harsh dermatological ...
Supriya Kumari Singh +4 more
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Journal of the American Academy of Dermatology, 1987
This review is an update on the literature accumulated over the past 10 years following the original observation that azelaic acid, a naturally occurring and nontoxic C9 dicarboxylic acid, possesses significant biologic properties and a potential as a therapeutic agent.
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This review is an update on the literature accumulated over the past 10 years following the original observation that azelaic acid, a naturally occurring and nontoxic C9 dicarboxylic acid, possesses significant biologic properties and a potential as a therapeutic agent.
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Advanced Materials Research, 2014
Azelaic (AZ) acid is a non antibiotic drug used for an acne treatment. The AZ dry emulsion power was prepared by mixing power of AZ with dry emulsion base. The 20% AZ cream was obtained by addition of water into powder mixture with a ratio of 1:1 by weight.
Somlak Kongmuang +3 more
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Azelaic (AZ) acid is a non antibiotic drug used for an acne treatment. The AZ dry emulsion power was prepared by mixing power of AZ with dry emulsion base. The 20% AZ cream was obtained by addition of water into powder mixture with a ratio of 1:1 by weight.
Somlak Kongmuang +3 more
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Percutaneous absorption of azelaic acid in humans
Experimental Dermatology, 1992Abstract Six healthy male volunteers received a single topical treatment with 5 g of an anti‐acne cream containing 20% azelaic acid (AzA) onto the face, the chest and the upper back. One week later 1 g of AzA was given orally to the same subjects as aqueous microcrystalline suspension.
U, Täuber, C, Weiss, H, Matthes
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Azelaic Acid Has Antimycotic Properties in vitro
Dermatology, 1993Azelaic acid is a therapeutic agent with well-known antibacterial properties, but its antimycotic effect has not yet been investigated systematically. In this study we have used an agar dilution technique to test the inhibitory effect of azelaic acid upon common dermatophytes, Scopulariopsis brevicaulis, Candida albicans, Candida glabrata and ...
J, Brasch, E, Christophers
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Journal of the Dermatology Nurses' Association, 2018
ABSTRACT By definition, a drug is a medicine or substance that exerts a physiologic effect on an organism. In dermatology, various medications and substances are utilized on a daily basis, ranging from topical treatments to anesthetics in micrographic surgery.
Mary Caroline Young, Patrick M. Zito
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ABSTRACT By definition, a drug is a medicine or substance that exerts a physiologic effect on an organism. In dermatology, various medications and substances are utilized on a daily basis, ranging from topical treatments to anesthetics in micrographic surgery.
Mary Caroline Young, Patrick M. Zito
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Azelaic acid--biochemistry and metabolism.
Acta dermato-venereologica. Supplementum, 1989Medium chain length dicarboxylic acids (DA) from C8 to C13 are competitive inhibitors of tyrosinase in vitro. The introduction of electron acceptor groups or electron donor groups into the 2 and/or the 8 position of the molecule enhances or reduces respectively the inhibitory effects of DA.
Passi, S +4 more
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Combination azelaic acid therapy for acne vulgaris
Journal of the American Academy of Dermatology, 2000There is no topical antiacne medication that acts against all four of the major pathophysiologic features of acne: hyperkeratinization, sebum production, bacterial proliferation, and inflammation. Topical azelaic acid cream helps both to normalize keratinization and to reduce the proliferation of Propionibacterium acnes, and has proven to be effective ...
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