Results 151 to 160 of about 28,418 (220)

Engagement of a Neighboring Lys Residue by a Salicylaldehyde‐Modified Glycomimetic Ligand Enables Potent and Selective Binding to DC‐SIGN Over L‐SIGN

ChemistryEurope, Volume 4, Issue 5, May 2026.
Mannose derivatives connected to the aminophilic salicylaldehyde tag show high binding affinity for C‐type lectin DC‐SIGN, favored by an imine bond with a protein's Lys residue in the ligand binding site. This reversible‐covalent binding interaction enables ligand selectivity for DC‐SIGN over the closely related L‐SIGN.
Sara Pollastri, Clara Delaunay, Giulia Antonini, Carine Froment, Michel Thépaut, Davide Pasquali, Sarah Mazzotta, Laura Belvisi, Julien Marcoux, Franck Fieschi, Alberto Dal Corso, Anna Bernardi   +11 more
wiley   +1 more source

Untargeted Identification of Alkyne-Containing Natural Products Using Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reactions Coupled to LC-MS/MS. [PDF]

J Nat Prod, 2022
Back D, Shaffer BT, Loper JE, Philmus B.
europepmc   +1 more source

Polyoxometalates for Health, Electronics, Energy, and the Environment: Challenges, Opportunities, and Future Horizons

ChemistryEurope, Volume 4, Issue 5, May 2026.
Polyoxometalates (POMs), illustrated as lemon‐like cars racing along a winding road, symbolize the accelerating progress of POM research toward technological applications. Global research communities, recent advances, and emerging opportunities highlight how coordinated efforts drive the transition of POM science from molecular discovery to deployable ...
Kirill Monakhov, Stanislav K. Petrovskii, De‐Liang Long, May Nyman, Axel Kahnt, Jonas Warneke, Chris Ritchie, Tatjana N. Parac‐Vogt, Scott G. Mitchell, Yu‐Fei Song, Marco Moors, Anna Proust, Dominique Vuillaume, Masahiro Sadakane, Graham N. Newton, Haralampos N. Miras   +15 more
wiley   +1 more source

The Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction: Why Two Is Faster than One. [PDF]

Chemphyschem
Vermeeren P.
europepmc   +1 more source

Strain-Promoted Azide-Alkyne Cycloaddition-Based PSMA-Targeting Ligands for Multimodal Intraoperative Tumor Detection of Prostate Cancer. [PDF]

Bioconjug Chem, 2022
Derks YHW, Rijpkema M, Amatdjais-Groenen HIV, Loeff CC, de Roode KE, Kip A, Laverman P, Lütje S, Heskamp S, Löwik DWPM.   +9 more
europepmc   +1 more source

Dual Cluster‐Surface Click Chemistries on Silver Nanoclusters

Small Science, Volume 6, Issue 5, May 2026.
In this report, two new structures of clickable anion templated silver nanoclusters (NCs) equipped with azide functional groups capable of cluster surface click reactions are described. It is demonstrated for the first time the Staudinger–Bertozzi ligation and dual click reactions Staudinger–Bertozzi ligation‐strain‐promoted azide–alkyne cycloadditions
Carolina Vega Verduga, Jack E. Bowman, Jeffrey D. Henderson, Paul D. Boyle, John F. Corrigan, Mark S. Workentin   +5 more
wiley   +1 more source

Investigation Into the Dynamics of the Cupula in the Vestibular Organ of Adult Zebrafish Using Metabolic Glycoengineering

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
The cupula is a membrane within the vestibular organ that senses rotatory accelerations of the head. Metabolic glycoengineering in combination with bioorthogonal labeling demonstrates that in adult zebrafish – being a model for the human inner ear – this membrane is constantly renewed.
Hans Scherer, Andrea Jüngst, Verena F. Schöwe, Anne‐Katrin Gronewald, Valentin Wittmann   +4 more
wiley   +2 more sources

Terminal and Internal Alkyne Complexes and Azide-Alkyne Cycloaddition Chemistry of Copper(I) Supported by a Fluorinated Bis(pyrazolyl)borate. [PDF]

Molecules, 2021
Noonikara-Poyil A, Muñoz-Castro A, Dias HVR.   +2 more
europepmc   +1 more source

Zwitterionic Mn(III)‐Tetraphenyl Porphyrins: Water‐Soluble MRI Contrast Agents with High Relaxivity

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Mn(III)‐based contrast agents (MBCAs) are promising and potentially safer alternatives to the Gd(III)‐based contrast agents (GBCAs) currently used in MRI. This study reports the synthesis, physicochemical characterization and first in vivo application of novel Mn(III)‐tetraphenylporphyrin chelates, bearing zwitterionic sulfobetaine or N‐oxide groups ...
Darius Ludolfs, Lennart F. V. Spickschen, Stefanie Bredehöft, Verena R. Schulze, Marie Oest, Samila Leon Chaviano, Neus Feliu, Markus Fischer, Marc‐André Fortin, John V. Frangioni, Wolfgang Maison   +10 more
wiley   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources