Results 141 to 150 of about 12,849 (199)

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull   +11 more
wiley   +1 more source

Bioactive Polymeric Scaffolds: Multivalent Functionalization by Thermal Azide-Alkyne Cycloaddition with Alkynyl Dicarbamates. [PDF]

open access: yesBiomacromolecules
Tawara MH   +6 more
europepmc   +1 more source

Ligand‐Dependent Locally Excited and Charge‐Transfer Emission in Linear Copper(I) Mesoionic Carbene Luminophores

open access: yesAdvanced Optical Materials, Volume 14, Issue 37, 9 October 2026.
Ligand engineering enables precise control of emission in linear Cu(I) complexes by tuning donor–acceptor interactions between electron‐rich amines and π‐accepting mesoionic carbenes. Naphthyl‐substituted carbenes promote locally excited phosphorescence with vibronic structure, whereas electron‐rich amides combined with electron‐poor carbenes favor ...
Felix León   +7 more
wiley   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao   +10 more
wiley   +1 more source

Design and Synthesis of Novel Biginelli Adducts: Anticancer Activity and In Silico Study

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Compound 8n emerged as the most potent agent against MCF‐7 cells, inducing apoptosis and cell cycle arrest. Molecular docking identified Eg5 kinesin as a potential target, highlighting these derivatives as promising leads for cancer therapeutics.
Aida Iraji   +6 more
wiley   +1 more source

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