Results 131 to 140 of about 12,849 (199)

Effective microwave-assisted approach to 1,2,3-triazolobenzodiazepinones via tandem Ugi reaction/catalyst-free intramolecular azide-alkyne cycloaddition. [PDF]

open access: yesBeilstein J Org Chem, 2021
Mazur MO   +8 more
europepmc   +1 more source

Reactivity of 2<i>H</i>-Azirines in Copper-Catalyzed Azide-Alkyne Cycloaddition Reactions. [PDF]

open access: yesOrg Lett
Janecký L   +5 more
europepmc   +1 more source

Conditional Copper-Catalyzed Azide-Alkyne Cycloaddition by Catalyst Encapsulation. [PDF]

open access: yesAngew Chem Int Ed Engl, 2020
Brevé TG   +7 more
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon   +9 more
wiley   +1 more source

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