Results 111 to 120 of about 12,849 (199)

Biotin‐ and Chloroalkane‐Modified Nucleotides for Dual Display of Proteins on DNA Through Streptavidin and Halotag Binding

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Modified 2’‐deoxy‐7‐deazaadenosine bearing a chlorohexyl moiety and 2’‐deoxycytidine nucleotides bearing biotin were used in the enzymatic synthesis of dually modified dsDNAs that served as scaffolds for display of halotag and monomeric streptavidin proteins.
Giammarco Liuni, Lenka Poštová Slavětínská, Miroslav Hájek, Veronika Raindlová, Michal Hocek   +4 more
wiley   +2 more sources

Mechanochemical Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC). [PDF]

J Org Chem
Kasprzak A.
europepmc   +1 more source

Recent Advances in Copper-Based Solid Heterogeneous Catalysts for Azide-Alkyne Cycloaddition Reactions. [PDF]

Int J Mol Sci, 2022
Aflak N, Ben El Ayouchia H, Bahsis L, Anane H, Julve M, Stiriba SE.   +5 more
europepmc   +1 more source

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

Journal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo, Françoise Illien, Fabienne Burlina, Barbara Biondi   +3 more
wiley   +1 more source

Copper-catalyzed enantioselective interrupted azide-alkyne cycloaddition to access axially chiral diaryl ethers. [PDF]

Chem Sci
Wu R, Chen L, Chen Y, Wu Q, Chen Q, Lin A, Yao H, Li Q, Gao S.   +8 more
europepmc   +1 more source

Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) by Functionalized NHC-Based Polynuclear Catalysts: Scope and Mechanistic Insights. [PDF]

Organometallics, 2022
González-Lainez M, Gallegos M, Munarriz J, Azpiroz R, Passarelli V, Jiménez MV, Pérez-Torrente JJ.   +6 more
europepmc   +1 more source

Toward Ideal Proximity‐Driven Reactions in Chemical Biology

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
Building on established principles of molecular templation, this perspective explores how molecular recognition can control chemical reactivity in space and time and outlines the design principles of an ideal proximity‐driven reaction for chemical biology.
Dominik Schauenburg
wiley   +1 more source

Azide-Alkyne Cycloaddition Catalyzed by Copper(I) Coordination Polymers in PPM Levels Using Deep Eutectic Solvents as Reusable Reaction Media: A Waste-Minimized Sustainable Approach. [PDF]

ACS Omega, 2023
Sethi S, Jana NC, Behera S, Behera RR, Bagh B.   +4 more
europepmc   +1 more source

Exploring the Copper(I)-Catalyzed Azide-Alkyne Cycloaddition: A Unified Reaction Valley Approach and Local Vibrational Mode Study. [PDF]

J Phys Chem A
McKenna L, Sexton TM, Freindorf M, Kraka E.   +3 more
europepmc   +1 more source

Catalytic Enantioselective Construction of Planar Chiral Heterocyclic [2.2]Paracyclophanes Enabled by Copper-Catalyzed Desymmetric Azide-Alkyne Cycloaddition. [PDF]

Nat Commun
Li ZZ, Feng YM, Zhang KF.
europepmc   +1 more source