Results 171 to 180 of about 12,849 (199)

Force‐Induced Control of Circularly Polarized Luminescence With Rotaxane Architecture

open access: yesAngewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Force‐induced reversible on/off switching of circularly polarized luminescence is achieved with a rotaxane‐based supramolecular mechanophore. The mechanophore, featuring a chiral helicene luminophore, is incorporated as a first network cross‐linker into a double‐network organogel.
Keigo Nonaka   +10 more
wiley   +2 more sources

Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi   +6 more
wiley   +1 more source

Successive Azide and DNA Functionalization for Reversible and Controlled Association of Single‐Wall Carbon Nanotubes

open access: yesChemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
A newly synthesized bifunctional azide—diazonium linker allows robust one‐step introduction of azido groups to single‐wall carbon nanotubes. Versatility of the azido groups as reactive handles is demonstrated by further derivatization with 6‐carboxyfluorescein and oligonucleotides.
Razieh Moosavi   +6 more
wiley   +1 more source

Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition

open access: yesAngewandte Chemie, Volume 138, Issue 38, 14 September 2026.
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando   +10 more
wiley   +2 more sources

Ratiometric pH‐Responsive and Biomimetic Microparticles for Quantitative Monitoring of Phagosomal Acidification

open access: yesChemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
A series of hydrosoluble BODIPY pH probes allows building biomimetic pH sensors based on micrometric oil‐in‐water droplets. The ratiometric fluorescence output offers quantitative information on the evolution of pH during phagosome maturation. ABSTRACT We present a modular biomimetic fluorescent sensing platform designed to precisely interrogate the ...
Sophie Michelis   +5 more
wiley   +1 more source

Diarylethene‐Containing Photoswitchable Analogues of Tubulysins—Design, Synthesis, Biological, and Structural Evaluation

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 35, 19 September 2026.
Diarylethene‐containing cyclic tubulysin analogues were designed, synthesized, and evaluated as light‐responsive cytotoxic agents. One analogue showed reversible photoswitching, photoregulated tubulin polymerization inhibition, and photoform‐dependent cytotoxicity.
Anna Iampolska   +9 more
wiley   +1 more source

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 38, 14 September 2026.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner   +5 more
wiley   +1 more source

Oxadiazolone‐Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II‐Induced Vascular Contraction

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
A novel series of candidate AT1 receptor antagonists based on oxadiazolone‐triazole scaffolds was designed and synthesized. Most compounds reduced angiotensin II‐induced vascular contraction in an initial biological screening, with compound 7f emerging as the most active derivative.
Larissa F. L. Ferreira   +5 more
wiley   +1 more source
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Reversible and Irreversible [2+2] Cycloaddition Reactions of Heteroallenes to a Gallaphosphene

Angewandte Chemie - International Edition, 2021
Mahendra Kumar Sharma   +2 more
exaly  

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