Results 251 to 260 of about 29,405 (265)

Electronic effects of ruthenium-catalyzed [3+2]-cycloaddition of alkynes and azides

open access: green, 2010
Duen‐Ren Hou   +4 more
openalex   +2 more sources

From Molecule to Meaning: Click and Bioorthogonal Chemical Reporters for Plant Systems, Biological Imaging, and Artistic Expression

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
At the intersection of chemical biology, plant imaging, and contemporary art, this review introduces the concept of chembioart. By tracing how chemical reporters illuminate plant biomolecules in vivo, their role not only in advancing scientific understanding but also in inspiring transdisciplinary collaborations and visual expression is highlighted ...
Marie Hinnebo   +4 more
wiley   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh   +7 more
wiley   +1 more source

Selection and Characterization of SARS‐CoV‐2 Spike Binding Clickmers

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Split‐combine click‐systematic evolution of ligands by exponential enrichment against wild‐type SARS‐CoV‐2 spike glycoprotein yields benzofuran‐ and indole‐functionalized DNA aptamers (clickmers). These clickmers retain specific binding to multiple variants with nanomolar affinity, and the 31 nt indole‐functionalized truncate T2 retains binding to ...
Nima Moradzadeh   +7 more
wiley   +1 more source

Remote Conformational Control of a Chloride‐Binding Site

open access: yesChemistryEurope, Volume 4, Issue 1, January 2026.
Chloride‐binding foldamers have been developed that have stereogenic C‐ and N‐terminal groups separated by a helical α‐aminoisobutyric acid (Aib) body. Chloride affinity is sensitive to the sense and strength of screw‐sense induction by each N‐terminal residue.
Rhodri Ll. Evans   +6 more
wiley   +1 more source

The Chemistry of Subphthalocyanines: Synthetic Strategies for their Axial, Peripheral, and Remote Postfunctionalization

open access: yesChemistryEurope, Volume 4, Issue 1, January 2026.
From axial and peripheral reactivity to remote derivatization, the chemical versatility of subphthalocyanines (SubPcs) renders them ideal scaffolds for the design of advanced functional materials. This review assembles the synthetic toolbox, key reaction conditions, and future challenges in SubPc functionalization, guiding the development of next ...
Marta Gómez‐Gómez   +4 more
wiley   +1 more source

Proximity‐Induced Ligation of Noncomplementary Oligonucleotides Triggered by Charge‐Transfer Interactions

open access: yesChemistryEurope, Volume 4, Issue 1, January 2026.
Charge‐transfer assisted ligation (CTAL) enables ultrafast CuAAC and SPAAC conjugation of a tetra‐DiAlkoxyNaphthalene (DAN4)‐azide and a noncomplementary tetraNaphthaleneDiImide (NDI4)‐alkyne oligonucleotide under dilute conditions, and the reaction can be carried out tracelessly by subsequently removing the tags.
Laura Nicollet   +4 more
wiley   +1 more source

Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen

open access: yesChemMedChem, Volume 21, Issue 1, January 2026.
It is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Aylin Berwanger   +10 more
wiley   +1 more source

Advanced Macromolecular Architectures via Inorganic Polymers

open access: yesMacromolecular Rapid Communications, Volume 47, Issue 2, 23 January 2026.
From linear chains to advanced macromolecular architectures, this review explores how innovations in inorganic polymers unlock new structural and functional capabilities. Emphasizing modern synthetic strategies and unique architectural designs, it highlights the emerging potential of main‐group element systems as next‐generation alternatives to ...
Edip Ajvazi   +3 more
wiley   +1 more source

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