Results 171 to 180 of about 15,577 (237)
ABSTRACT The approval requirements in new regions that do not require domestic clinical data and the clinical data evaluation of multi‐regional clinical trials (MRCTs) and foreign clinical trials (FCTs) in the Japanese approval review processes for antimicrobial medicines were explored.
Rumiko Shimazawa, Masayuki Ikeda
wiley +1 more source
Guide for Mayors and Local Governments / Guía del Alcalde en su Govierno Local [PDF]
Benguigui, Y, Drasbek, C, Chico, RM
core
Pulmonary alveolar proteinosis (PAP) is an ultra‐rare lung disease that can recur even years after bilateral lung transplantation, as in this 73‐year‐old man whose diagnosis was delayed by PAS‐negative BAL and overlapping opportunistic infections (Nocardia, MAC, Aspergillus). Despite initially normal post‐transplant spirometry, he developed progressive
Omar Lopez +3 more
wiley +1 more source
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley +1 more source
ABSTRACT Objective Interstitial cystitis/bladder pain syndrome (IC/BPS) is linked to bladder and/or pelvic pain, pressure, and discomfort with urinary frequency. Despite guidelines, there is a need for better treatment options. This study analyzed patient demographics, clinical characteristics, and treatment patterns for medications and procedures in ...
Jaromir Mikl +8 more
wiley +1 more source
Guide for Teachers and Schools / Guía del Maestro y su Esquela [PDF]
Benguigui, Y, Drasbek, C, Chico, RM
core
ABSTRACT When evaluating treatment effects in progressive disease clinical trials, analyses of time to recurrent or terminal events largely ignore (or separately analyze) functional measures of disease progression over time. For instance, in pulmonary research settings, treatment may impact recurrent times‐to‐hospitalization, mortality and pulmonary ...
Lantian Xu, Susan Murray
wiley +1 more source
ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill +3 more
wiley +1 more source
Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore +2 more
wiley +1 more source
ABSTRACT Objectives To compare the trueness of implant placement in novice surgeons using dynamic computer‐assisted implant surgery (d‐CAIS) versus a non‐guided approach, assessing surgery time efficiency and patient‐reported outcomes, including satisfaction, postoperative pain, and quality of life. Material and Methods A double‐arm randomized clinical
Víctor Ruiz‐Romero +5 more
wiley +1 more source

