Results 41 to 50 of about 96,342 (294)

Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study

medRxiv, 2020
Background: Hydroxychloroquine has recently received Emergency Use Authorization by the FDA and is currently prescribed in combination with azithromycin for COVID-19 pneumonia.
J. Lane, J. Weaver, K. Kostka, T. Duarte-Salles, M. T. Abrahão, H. Alghoul, Osaid Alser, MD, MSc (Oxon), T. Alshammari, P. Biedermann, E. Burn, P. Casajust, M. Conover, A. Culhane, A. Davydov, S. Duvall, D. Dymshyts, S. Fernández Bertolín, K. Fister, J. Hardin, L. Hester, G. Hripcsak, S. Kent, S. Khosla, S. Kolovos, Christophe Gerard Lambert, J. ver der Lei, A. Londhe, K. Lynch, R. Makadia, A. Margulis, M. Matheny, P. Mehta, D. Morales, H. Morgan-Stewart, M. Mosseveld, D. Newby, F. Nyberg, A. Ostropolets, R. W. Park, A. Prats-Uribe, G. Rao, Reich   +41 more
semanticscholar   +1 more source

Azithromycin in viral infections

Reviews in Medical Virology, 2020
Azithromycin (AZM) is a synthetic macrolide antibiotic effective against a broad range of bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti‐inflammatory properties, it has been given to patients with the ...
Madeleine E Oliver, T. Hinks
semanticscholar   +1 more source

Azithromycin suppresses Th1- and Th2-related chemokines IP-10/MDC in human monocytic cell line

Journal of Microbiology, Immunology and Infection, 2019
Background: Cytokines and chemokines play critical roles in the pathogenesis of asthma. Azithromycin, a macrolides, is frequently used in asthmatic children with lower respiratory tract infection and is reported having anti-inflammatory and ...
Chang-Hung Kuo, Min-Sheng Lee, Hsuan-Fu Kuo, Yi-Ching Lin, Chih-Hsing Hung   +4 more
doaj   +1 more source

Safety of azithromycin in infants under six months of age in Niger: A community randomized trial. [PDF]

PLoS Neglected Tropical Diseases, 2018
BACKGROUND:Mass azithromycin distribution reduces under-5 child mortality. Trachoma control programs currently treat infants aged 6 months and older. Here, we report findings from an infant adverse event survey in 1-5 month olds who received azithromycin
Catherine E Oldenburg, Ahmed M Arzika, Ramatou Maliki, Mohamed Salissou Kane, Elodie Lebas, Kathryn J Ray, Catherine Cook, Sun Y Cotter, Zhaoxia Zhou, Sheila K West, Robin Bailey, Travis C Porco, Jeremy D Keenan, Thomas M Lietman, MORDOR Study Group   +14 more
doaj   +1 more source

Azithromycin in COVID-19 Patients: Pharmacological Mechanism, Clinical Evidence and Prescribing Guidelines

Drug Safety, 2020
The global COVID-19 pandemic has led to a race to find medications that can improve the prognosis of the disease. Azithromycin, in association with hydroxychloroquine or chloroquine, has been proposed as one such medication.
J. Sultana, P. Cutroneo, S. Crisafulli, G. Puglisi, G. Caramori, G. Trifirò   +5 more
semanticscholar   +1 more source

Immunomodulatory Effects of Azithromycin Revisited: Potential Applications to COVID-19

Frontiers in Immunology, 2021
The rapid advancement of the COVID-19 pandemic has prompted an accelerated pursuit to identify effective therapeutics. Stages of the disease course have been defined by viral burden, lung pathology, and progression through phases of the immune response ...
V. Venditto, Dalia Haydar, A. Abdel-Latif, J. Gensel, M. Anstead, Michelle G. Pitts, Jarrod W. Creameans, Timothy J Kopper, Chi-Guen Peng, D. Feola   +9 more
semanticscholar   +1 more source

Rationale for azithromycin in COVID-19: an overview of existing evidence

BMJ Open Respiratory Research, 2021
Azithromycin has rapidly been adopted as a repurposed drug for the treatment of COVID-19, despite the lack of high-quality evidence. In this review, we critically appraise the current pharmacological, preclinical and clinical data of azithromycin for ...
I. Gyselinck, W. Janssens, P. Verhamme, R. Vos   +3 more
semanticscholar   +1 more source

Minimum inhibitory concentrations of azithromycin in clinical isolates of Mycobacterium avium complex in Japan

Microbiology Spectrum
The latest guidelines include azithromycin as a preferred regimen for treating Mycobacterium avium complex (MAC) pulmonary disease. However, serially collected susceptibility data on clinical MAC isolates are limited, and no breakpoints have been ...
Yoshifumi Uwamino, Wataru Aoki, Rika Inose, Yuka Kamoshita, Kei Mikita, Ho Namkoong, Tomoyasu Nishimura, Hiromichi Matsushita, Naoki Hasegawa   +8 more
doaj   +1 more source

Azithromycin for COVID-19: More Than Just an Antimicrobial?

Clinical drug investigation, 2020
The COVID-19 infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health issue worldwide, as no vaccines or drugs for prevention and treatment have been approved so far, except remdesivir that has been recently ...
N. Bleyzac, S. Goutelle, L. Bourguignon, M. Tod   +3 more
semanticscholar   +1 more source

Creation of an assessment system for measuring the bitterness of azithromycin-containing reverse micelles

Asian Journal of Pharmaceutical Sciences, 2018
We aimed to develop a novel method for assessing the bitterness of azithromycin-containing reverse micelles (AM-containing RMs). Azithromycin-containing reverse micelles were prepared by processing Lipoid E80 and medium chain triglycerides via a freeze ...
Ri Huang, Yadan Zhang, Tao Wang, Liao Shen, Zhen Zhang, Yang Wang, Dongqin Quan   +6 more
doaj   +1 more source