From crops to clinic: the impact of dual azole use on antifungal resistance in <i>Candida</i> and <i>Candida</i> associated yeasts. [PDF]
Allison JC, Hyland EM.
europepmc +1 more source
Cytochrome P-450 as a target of azole antifungal agents.
Yuzou YOSHIDA
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Ab initio Study of Nitrogen-14 Nuclear Quadrupole Coupling and NMR Signal Linewidths in Some Azoles [PDF]
Michał Jaszuński, Antonio Rizzo
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Abstract This publication presents the geometries of 157 nitro‐ and polynitropyrazoles. Among these, 109 compounds were theoretically studied using mainly the B3LYP/6–311++G(d,p) level of theory. Three‐parameter Lee‐Yang‐Parr (B3LYP) is a density functional theory (DFT) method widely used in computational chemistry and constitutes an acceptable ...
Rosa M. Claramunt +3 more
wiley +1 more source
A series of 13 hybrid molecules of both lead structures were prepared using reductive amination as key reaction step. The antimycotic potency of the resulting compounds was evaluated against yeast and mold species. Two compounds showed remarkable potency against several yeasts, and even against Candida krusei.
Marie‐Christin Hain +4 more
wiley +1 more source
Stereoselective interaction of the azole antifungal agent SCH39304 with the cytochrome P-450 monooxygenase system isolated from Cryptococcus neoformans [PDF]
David C. Lamb +3 more
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Comprehensive insights into the role of nanocarriers in advancing azole-based ocular therapeutics. [PDF]
Sil D +7 more
europepmc +1 more source
Aims The clinical effectiveness of tezacaftor‐ivacaftor in children with cystic fibrosis (cwCF) varies; some patients respond while others do not or have adverse effects. The pharmacokinetics (PK) of tezacaftor‐ivacaftor are inadequately published, especially in children.
Steffie E. M. Vonk +7 more
wiley +1 more source
Role and mechanism of hexyl-aminolevulinate ethosome-mediated antimicrobial photodynamic therapy in reversing fluconazole resistance in <i>Nakaseomyces glabrata</i> (<i>Candida glabrata</i>). [PDF]
Wang Y +7 more
europepmc +1 more source

