Results 181 to 190 of about 72,034 (334)

Removing the physician from the equation: Patient‐controlled, home‐based therapeutic drug self‐monitoring of tacrolimus

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 6, Page 1560-1568, June 2025.
The dosing of tacrolimus, which forms the backbone of immunosuppressive therapy after kidney transplantation, is complex. This is due to its variable pharmacokinetics (both between and within individual patients), narrow therapeutic index, and the severe consequences of over‐ and underexposure, which may cause toxicity and rejection, respectively ...
Marinus Hazenbroek   +6 more
wiley   +1 more source

An Overview of Pyrazole-Tetrazole-Based Hybrid Compounds: Synthesis Methods, Biological Activities and Energetic Properties

open access: yesOrganics
Pyrazole and tetrazole are among the most important heterocyclic members of the azole family. Over the past decade, these N-heterocycles and their derivatives have demonstrated specific properties that give them potent applications in several fields such
Mounir Cherfi   +4 more
doaj   +1 more source

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

open access: yesJournal of Antimicrobial Chemotherapy, 2018
A. Chowdhary   +15 more
semanticscholar   +1 more source

Comparative efficacy of selenoureido carbonic anhydrase inhibitors and azole antifungal drugs against clinical isolates of Malassezia pachydermatis

open access: yesVeterinary Dermatology, Volume 36, Issue 3, Page 302-313, June 2025.
Background – Malassezia pachydermatis (MP) is implicated in severe dermatitis and otitis externa (OE) of companion animals and recently gained attention for its increasing resistance to azole compounds. For this reason, developing novel therapeutic strategies is of great interest. In a previous work, we used reference yeast isolates to evaluate several
Costanza Spadini   +11 more
wiley   +1 more source

Photophysical and Chiroptical Properties of Pyrazino‐Phenanthroline‐Helicene Derivative and its Rhenium(I) Complex

open access: yesChemistry – An Asian Journal, Volume 20, Issue 10, May 15, 2025.
The preparation and characterization of the first helical pyrazino‐phenanthroline ligand, namely [4]helicene‐pyrazino[2,3‐f][1,10]phenanthroline (H4PP) and its corresponding Re(CO)3Cl complex (Re‐H4PP) are described. The photophysics and chiroptics (circular dichroism and circularly polarized luminescence) of these new chiral systems are thoroughly ...
Debsouri Kundu   +5 more
wiley   +1 more source

The impact of weather variability and climate change on pesticide applications in the US - An empirical investigation [PDF]

open access: yes
Weather variability and climate change affect the application of pesticides in agriculture, in turn impacting the environment. Using panel data regression for the US, we find that weather and climate differences significantly influence the application ...
Nikolinka G. Koleva   +2 more
core  

Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India. [PDF]

open access: yes, 2019
Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India.
Crawford, Emily D   +12 more
core   +1 more source

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