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Antifungal Azoles: Old and New
Pediatric Infectious Disease Journal, 2011Management of fungal infections is complex with increasing choice of antifungals. Mortality and morbidity are significant despite treatment. Azoles are commonly used compounds which inhibit fungal lanosterol 14 demethylase, thereby depleting ergosterol in the fungal cell membrane with the accumulation of lanosterol precursors.
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Revista iberoamericana de micologia, 2007
Azole antifungals have different pharmacokinetic characteristics: complete oral absorption for Voriconazole, and to a lesser extent for fluconazole. The absorption of posaconazole and itraconazole increases with food intake. All of them have high tissue distribution with low plasma concentrations, especially low in the case of posaconazole and ...
José Ramón, Azanza +2 more
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Azole antifungals have different pharmacokinetic characteristics: complete oral absorption for Voriconazole, and to a lesser extent for fluconazole. The absorption of posaconazole and itraconazole increases with food intake. All of them have high tissue distribution with low plasma concentrations, especially low in the case of posaconazole and ...
José Ramón, Azanza +2 more
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Nickel‐Catalyzed C−H Bond Functionalization of Azoles and Indoles
Chemical Record, 2021Benudhar Punji
exaly
Light‐Promoted Copper‐Catalyzed Enantioselective Alkylation of Azoles
Angewandte Chemie - International Edition, 2021Guozhu Zhang
exaly
Basicity and acidity of azoles: the annelation effect in azoles
Journal of the American Chemical Society, 1988Javier. Catalan +8 more
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Effect of adsorption of some azoles on copper passivation in alkaline medium
Corrosion Science, 2002V Lakshminarayanan
exaly