Results 201 to 210 of about 23,046 (254)
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Synthesis of New Azolyl Azoles and Azinyl Azoles.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Balkis Al-Saleh   +2 more
openaire   +1 more source

Azole resistance inCandida

European Journal of Clinical Microbiology & Infectious Diseases, 1997
Resistance of Candida to azoles is an increasing problem. Susceptibility testing of Candida against fluconazole and ketoconazole is now feasible and desirable. Good correlation of resistance in vitro with clinical failure of fluconazole therapy has now been shown in mucosal candidiasis.
Denning, D.W., Baily, G.G., Hood, S.V.
openaire   +3 more sources

Azoles and AIDS

The Journal of Infectious Diseases, 1990
The treatment of opportunistic infections in AIDS patients is changing rapidly as new drugs become available and new studies of old drugs are completed. I have tried to use the AIDS commentaries to keep up with these advances. Since fluconazole has just recently been approved by the US Food and Drug Administration, I asked Dr. Robert A.
openaire   +2 more sources

Update on Azole Antifungals

Seminars in Respiratory and Critical Care Medicine, 2008
This is a comprehensive, clinically oriented review of the four commercially available triazoles: fluconazole, itraconazole, voriconazole, and posaconazole. Emphasis is placed in pharmacology, drug interactions, adverse events, antifungal activity, and the evolving perspective of their clinical use.
Dimitrios I, Zonios, John E, Bennett
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Emerging azole antifungals

Expert Opinion on Emerging Drugs, 2005
Systemic and superficial fungal infections have progressively emerged over the past few decades as an increasing cause of human disease, especially in the immunocompromised host. Control of fungal disease has proved difficult because few risk factors are potentially preventable; the population at highest risk for fungal disease, the immunocompromised ...
Anne, Chen, Jack D, Sobel
openaire   +2 more sources

Azole-resistant aspergillosis

Journal of Infection, 2015
Azole-resistance in Aspergillus fumigatus is emerging and is becoming an increasing problem in the management of aspergillosis. Two types of development of resistance have been described; resistance acquired during azole treatment in an individual patient and through environmental exposure to fungicides. The main molecular mechanism of azole resistance
openaire   +2 more sources

Azole Antifungal Agents

Clinical Infectious Diseases, 1992
The discovery of the antifungal activity of azole compounds represented an important therapeutic advance. Miconazole, ketoconazole, and fluconazole are currently commercially available, and itraconazole has undergone extensive clinical evaluation. Because of its limited activity and toxicity, miconazole has been replaced by newer agents.
openaire   +2 more sources

Azoles

2000
Abstract Systemic administration is accompanied by headache and somnolence in 10% of cases. Acute toxic psychosis with confusion, hallucinations, and delusions is rarely described with each agent (1,2). Intrathecal administration is associ ated with arachnoiditis, without ischemic myelopathy (3). The azole antifungal
openaire   +1 more source

Synthesis of N-(α-Fluorovinyl)azoles by the Reaction of Difluoroalkenes with Azoles

The Journal of Organic Chemistry, 2014
A mild and versatile method for the construction of C-N bonds by the reaction of (2,2-difluorovinyl)arenes with various N-H-containing heterocycles in the presence of K3PO4 has been developed. The reaction proceeded efficiently at room temperature (25 °C) affording the (E)-N-α-fluorovinyl derivatives of azoles 3 in good to excellent yields with ...
Yang, Xiong   +3 more
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Azoles

Reactions Weekly, 2009
George R. Thompson, Thomas F. Patterson
openaire   +2 more sources

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