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Azole Antifungal Agents [PDF]

, 2016
Azole antifungal agents, primarily the triazoles fluconazole, itraconazole, voriconazole and posaconazole, are in widespread clinical use for the management of systemic fungal infections. Their application in the prophylaxis against and treatment of systemic mycoses continues to evolve, with ongoing advancements in drug delivery, efficacy, monitoring ...
Nicolette R. Holt, Karin A Thursky
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ChemInform Abstract: AZOLE ALDEHYDE CONDENSATIONS

Chemischer Informationsdienst, 1973
AbstractDer Carbaldehyd (Ia), der, wie schon früher beschrieben, im festen Zustand als dimeres cyclisches Hemiaminal (Ib) vorliegt, reagiert mit einfachen alicyclischen Ketonen, wie (IIa), zu den Alkoholen (IIIa).
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Difluoromethylation of parent azoles

Journal of Fluorine Chemistry, 2018
Abstract The method for difluoromethylation of parent azoles, namely pyrrole, 1,2,3-triazole, 1,2,4-triazole and tetrazole was developed. Difluorometylation of pyrrole and 1,2,3-triazole was performed by action of chlorodifluoromethane. Sodium chlorodifluoroacetate was used as a difluoromethylation agent for 1,2,4-triazole and tetrazole.
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Basicity and Acidity of Azoles

1987
Publisher Summary This chapter provides a large collection of solution data and a thoroughly updated discussion of thermodynamic, kinetic, and structural results. This chapter covers aromatic azoles exclusively—that is, aromatic five-membered rings containing only carbon and nitrogen atoms, and their benzo derivatives.
Javier Catalán, José Elguero
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Antifungal Azoles: Old and New

Pediatric Infectious Disease Journal, 2011
Management of fungal infections is complex with increasing choice of antifungals. Mortality and morbidity are significant despite treatment. Azoles are commonly used compounds which inhibit fungal lanosterol 14 demethylase, thereby depleting ergosterol in the fungal cell membrane with the accumulation of lanosterol precursors.
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Azole antifungals

Clinics in Dermatology, 1989
H F, Merk, H, Mukhtar
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Basicity and acidity of azoles: the annelation effect in azoles

Journal of the American Chemical Society, 1988
J. H. Quian, Margarita Menéndez, Rosa M. Claramunt, Javier Catalán, José Laynez, Robert W. Taft, M. Taagepera, José Elguero, Frederick Anvia   +8 more
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Light‐Promoted Copper‐Catalyzed Enantioselective Alkylation of Azoles

Angewandte Chemie - International Edition, 2021
Guozhu Zhang, Chang Liu, Golrokh Akhgar
exaly  

Nickel‐Catalyzed C−H Bond Functionalization of Azoles and Indoles

Chemical Record, 2021
Benudhar Punji
exaly  

Azoles

1975
Robert M. Smith, Arthur E. Martell
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