Results 291 to 300 of about 41,065 (312)
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N-(Difluoroamino)azoles – a new class of N-substituted azoles
Mendeleev Communications, 1996AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
V. M. Vinogradov +3 more
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Azole antifungal agents, primarily the triazoles fluconazole, itraconazole, voriconazole and posaconazole, are in widespread clinical use for the management of systemic fungal infections. Their application in the prophylaxis against and treatment of systemic mycoses continues to evolve, with ongoing advancements in drug delivery, efficacy, monitoring ...
Nicolette R. Holt, Karin A Thursky
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Médecine et Maladies Infectieuses, 1984
Resume Les premiers azoles antifongiques possedent un spectre d'activite restreint. L'etonam (R 10100) etait actif contre les dermatophytes a la fois in vitro et in vivo par application topique. Le spectre antimycosique dans le traitement topique s'est elargi avec le miconazole et le clotrimazole.
P. A. J. Janssen, J. Van Cutsem
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Resume Les premiers azoles antifongiques possedent un spectre d'activite restreint. L'etonam (R 10100) etait actif contre les dermatophytes a la fois in vitro et in vivo par application topique. Le spectre antimycosique dans le traitement topique s'est elargi avec le miconazole et le clotrimazole.
P. A. J. Janssen, J. Van Cutsem
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Energetic Azolium Azolate Salts
Inorganic Chemistry, 2005Energetic salts comprising substituted imidazolium and 1,2,4-triazolium cations and 4,5-dinitro-imidazolate and 5-nitrotetrazolate anions were synthesized and characterized. On the basis of experimentally obtained heats of combustion, the calculated heats of formation range from deltaHf(o) degrees = 80 (3) to 1071 kJ/mol (13).
Jean'ne M. Shreeve +3 more
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Synthesis of Polynuclear Nonfused Azoles
Russian Journal of Organic Chemistry, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
A. V. Rokhin +4 more
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Emergence of Azole Resistance in Aspergillus
Seminars in Respiratory and Critical Care Medicine, 2015Resistance to the azole antifungals itraconazole, voriconazole, and posaconazole in Aspergillus species is a growing concern. This is especially alarming for A. fumigatus, where acquired resistance has been documented in patients with invasive disease caused by this species that were exposed to these agents, as well as in azole-naive individuals.
Thomas F. Patterson +1 more
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Basicity and Acidity of Azoles
1987Publisher Summary This chapter provides a large collection of solution data and a thoroughly updated discussion of thermodynamic, kinetic, and structural results. This chapter covers aromatic azoles exclusively—that is, aromatic five-membered rings containing only carbon and nitrogen atoms, and their benzo derivatives.
Javier Catalán, José Elguero
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Difluoromethylation of parent azoles
Journal of Fluorine Chemistry, 2018Abstract The method for difluoromethylation of parent azoles, namely pyrrole, 1,2,3-triazole, 1,2,4-triazole and tetrazole was developed. Difluorometylation of pyrrole and 1,2,3-triazole was performed by action of chlorodifluoromethane. Sodium chlorodifluoroacetate was used as a difluoromethylation agent for 1,2,4-triazole and tetrazole.
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ChemInform Abstract: AZOLE ALDEHYDE CONDENSATIONS
Chemischer Informationsdienst, 1973AbstractDer Carbaldehyd (Ia), der, wie schon früher beschrieben, im festen Zustand als dimeres cyclisches Hemiaminal (Ib) vorliegt, reagiert mit einfachen alicyclischen Ketonen, wie (IIa), zu den Alkoholen (IIIa).
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