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Multicenter surveillance of antifungal susceptibility of clinical Aspergillus isolates to conventional and novel antifungal agents in Taiwan, 2021–2023 [PDF]
Microbiology SpectrumPeriodic surveillance of antifungal susceptibility among Aspergillus isolates is essential to guide effective treatment. This multicenter study analyzed 550 clinical Aspergillus isolates collected in Taiwan from 2021 to 2023, primarily from the ...
Ming-I Hsieh +4 more
doaj +2 more sources
The role of azoles in the management of azole-resistant aspergillosis: From the bench to the bedside
Drug Resistance Updates, 2014 Azole resistance is an emerging problem in Aspergillus fumigatus and is associated with a high probability of treatment failure. An azole resistance mechanism typically decreases the activity of multiple azole compounds, depending on the mutation. As alternative treatment options are limited and in some isolates the minimum inhibitory concentration ...
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exaly +4 more sources
Azole Resistance in Aspergillus fumigatus: A Consequence of Antifungal Use in Agriculture?
Frontiers in Microbiology, 2017 Agricultural industry uses pesticides to optimize food production for the growing human population. A major issue for crops is fungal phytopathogens, which are treated mainly with azole fungicides.
Alix Coste, Yassine El Chazli
exaly +3 more sources
High incidence of azole resistance among Candida albicans and C. glabrata isolates in Northeastern Iran [PDF]
Current Medical Mycology, 2021 Background and Purpose: Resistance to antifungal drugs is increasing among Candida isolates from patients with vulvovaginal candidiasis (VVC). Lack of correct diagnosis of Candida causing VVC and the experimental use of antifungal drugs are the main ...
Hossein Zarrinfar +2 more
doaj +1 more source
Microbiology Spectrum, 2022 The emergence of antifungal resistance, especially to the most widely used azole class of ergosterol biosynthesis inhibitors, makes fungal infections difficult to treat in clinics and agriculture. When exposed to azoles, fungi can make adaptive responses
Chengcheng Hu +6 more
doaj +1 more source
Trichophyton: Changing nomenclature and practical implications
Indian Journal of Dermatology, 2023 Trichophyton interdigitale had been regarded as anthropophilic, mainly causing non-inflammatory tinea unguium and tinea pedis. T. mentagrophytes, thought to be zoophilic, were regarded as responsible for more inflammatory dermatophytosis.
Manas Chatterjee, Debatri Datta
doaj +1 more source
mSphere, 2022 Fungal infections contribute to over 1.5 million deaths annually, with Candida albicans representing one of the most concerning human fungal pathogens. While normally commensal in nature, compromise of host immunity can result in C.
Antonia C. Du Bois +12 more
doaj +1 more source
Frontiers in Endocrinology, 2023 Acute adrenal crisis classically presents with vomiting, altered sensorium, and hypotension. We describe a unique case manifesting with severe hypercalcemia. Addisonian crisis was unusually precipitated by fluconazole use.
Kuan Swen Choo +3 more
doaj +1 more source
Antifungal Activity of Minocycline and Azoles Against Fluconazole-Resistant Candida Species
Frontiers in Microbiology, 2021 Candida species are the most common fungal pathogens to infect humans, and can cause life-threatening illnesses in individuals with compromised immune systems.
Jingwen Tan +6 more
doaj +1 more source
Marine Drugs, 2021 Oceanapiside (OPS), a marine natural product with a novel bifunctional sphingolipid structure, is fungicidal against fluconazole-resistant Candida glabrata at 10 μg/mL (15.4 μM).
Doralyn S. Dalisay +2 more
doaj +1 more source