One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions [PDF]
Molecules, 2019 A one-pot synthesis of triazolobenzodiazepine-containing polycyclic compounds is introduced. The reaction process involves a decarboxylative three-component [3 + 2] cycloaddition of nonstabilized azomethine ylides, N-propargylation, and intramolecular ...
Xiaoming Ma +6 more
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Synergistic catalysis for cascade allylation and 2-aza-cope rearrangement of azomethine ylides [PDF]
Nature Communications, 2019 Metallated azomethine ylides are commonly used for the construction of N-heterocycles and α-amino acids. Here, the authors report a synergistic Cu/Ir-catalytic system that converts aldimine esters to a variety of chiral homoallylic amines via a cascade ...
Liang Wei +4 more
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Intramolecular Hydrogen Bond Activation: Thiourea-Organocatalyzed Enantioselective 1,3-Dipolar Cycloaddition of Salicylaldehyde-Derived Azomethine Ylides with Nitroalkenes. [PDF]
ACS Catal, 2018 An organocatalytic strategy for the synthesis of tetrasubstituted pyrrolidines with monoactivated azomethine ylides in high enantiomeric excess and excellent exo/endo selectivity is presented.
Esteban F +8 more
europepmc +7 more sources
Microwave‐Assisted [3 + 2] Cycloadditions of Azomethine Ylides. [PDF]
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
George Bashirhiardes +4 more
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Application of 1,3-Dipolar Reactions between Azomethine Ylides and Alkenes to the Synthesis of Catalysts and Biologically Active Compounds. [PDF]
European J Org Chem, 2018 The (3+2) cycloaddition between azomethine ylides and alkenes is an efficient, convergent and stereocontrolled method for the synthesis of unnatural pyrrolidine and proline scaffolds.
Arrastia I, Arrieta A, Cossío FP.
europepmc +3 more sources
Influence of Endo- and Exocyclic Heteroatoms on Stabilities and 1,3-Dipolar Cycloaddition Reactivities of Mesoionic Azomethine Ylides and Imines. [PDF]
J Org Chem, 2017 The geometries, stabilities, and 1,3-dipolar cycloaddition reactivities of 24 mesoionic azomethine ylides and imines were investigated using density functional theory calculations at the M06-2X/6-311+G-(d,p)/M06-2X/6-31G-(d) level.
Champagne PA, Houk KN.
europepmc +3 more sources
Stereoselective Ag‐Catalyzed 1,3‐Dipolar Cycloaddition of Activated Trifluoromethyl‐Substituted Azomethine Ylides [PDF]
, 2016 This is the peer reviewed version of the following article: Chemistry – A European Journal 22.14 (2016): 4952 - 4959, which has been published in final form at http://doi.org/10.1002/chem.201504869. This article may be used for non-commercial purposes in
A. Rubio‐Ponce +3 more
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Synthesis of Some New 3-Pyrrolidinylquinoline Derivatives via 1,3-Dipolar Cycloaddition of Stabilized Azomethine Ylides to Quinolinyl α , β - Unsaturated Ketones [PDF]
, 2010 International audienceN-Metallated azomethine ylide generated from methyl (E)-N-benzylideneglycinate, LiBr and triethylamine underwent cycloaddition to quinolyl α,β- unsaturated ketones with excellent diastereoselectivity to afford new functionalised 3 ...
Abdelmalek Bouraiou +5 more
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Catalytic asymmetric synthesis of diazabicyclo[3.1.0]hexanes by 1,3-dipolar cycloaddition of azomethine ylides with azirines [PDF]
, 2020 Substituted 1,3-diazabicyclo[3.1.0]hexanes with two contiguous quaternary stereocentres are readily prepared by catalytic asymmetric [3+2] cycloaddition of α-substituted iminoesters with azirines.
Alba Molina +3 more
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Enantioselective 1,3-Dipolar Cycloaddition Using (Z)-α-Amidonitroalkenes as a Key Step to the Access to Chiral cis-3,4-Diaminopyrrolidines [PDF]
Molecules, 2022 The enantioselective 1,3-dipolar cycloaddition between imino esters and (Z)-nitroalkenes bearing a masked amino group in the β-position was studied using several chiral ligands and silver salts.
Eduardo García-Mingüens +5 more
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