Results 211 to 220 of about 28,644 (231)

General Asymmetric Synthesis of Densely Functionalized Pyrrolidines via Endo-Selective [3+2] Cycloaddition of β-Quaternary-Substituted Nitroalkenes and Azomethine Ylides.

Journal of Organic Chemistry, 2020
A scalable endo-selective synthesis of 2,3,4,5-tetrasubstituted pyrrolidines via cycloaddition of nitroalkenes and azome-thine ylides is reported using a P,N-type ferrocenyl ligand and [Cu(OTf)]2·C6H6.
Stephen N. Greszler, Gang Zhao, Marek Buchman, Xenia B. Searle, Bo Liu, E. Voight   +5 more
semanticscholar   +1 more source

Synthesis of Spiro[indoline-pyridine]-dicarboxylates and Substituted Alkylidene Oxindoles by Azomethine Ylides and MBH Carbonates of Isatins.

Organic Letters
We have developed an efficient protocol for the synthesis of spiro[indoline-pyridine]dicarboxylates and substituted alkylidene oxindoles through [3 + 3] cycloaddition and Michael addition individually by azomethine ylides and various MBH carbonates of ...
Daqian Wang, Ting Tang, Jing Sun, Ying Han, Chaoguo Yan   +4 more
semanticscholar   +1 more source

A facile synthesis of novel polycyclic spiropyrrolidine oxindoles incorporating the 1,3-dipolar cycloaddition of azomethine ylides

, 2020
This study describes the synthesis of novel polycyclic spiropyrrolidine oxindoles through the 1,3-dipolar cycloaddition of azomethine ylides generated in situ with 3-(arylmethylene)-indolin-2-ones.
Krisztina E. Treuerné Balázs, M. Molnár, Z. Madarász, M. Nyerges   +3 more
semanticscholar   +1 more source

2-Azaallyl Anions, 2-Azaallyl Cations, 2-Azaallyl Radicals, and Azomethine Ylides.

Chemical Reviews, 2018
This review covers the use of 2-azaallyl anions, 2-azaallyl cations, and 2-azaallyl radicals in organic synthesis up through June 2018. Particular attention is paid to both foundational studies and recent advances over the past decade involving ...
Shaojian Tang, Xia Zhang, Jiayue Sun, D. Niu, J. Chruma   +4 more
semanticscholar   +1 more source

Double 1,3-Dipolar Cycloadditions of Two Nonstabilized Azomethine Ylides for Polycyclic Pyrrolidines.

Organic Letters, 2019
Nonstabilized azomethine ylides derived from decarboxylation of oxazolidin-5-ones were used for double 1,3-dipolar cycloadditions in diastereoselective synthesis of pyrrolidine-containing tetracyclic compounds.
Xiaofeng Zhang, W. Qiu, Jason J Evans, M. Kaur, J. Jasinski, Wei Zhang   +5 more
semanticscholar   +1 more source

Synthesis of Spiro[oxindole-3,2'-pyrrolidine] Derivatives from Benzynes and Azomethine Ylides through 1,3-Dipolar Cycloaddition Reactions.

Journal of Organic Chemistry, 2018
A novel synthetic strategy employing benzyne and azomethine ylides for the construction of spiro[oxindole-3,2'-pyrrolidine] derivatives has been achieved in good yields.
Heesun Ryu, J. Seo, H. Ko
semanticscholar   +1 more source

A Molecular Electron Density Theory Study of the Role of the Copper Metalation of Azomethine Ylides in [3 + 2] Cycloaddition Reactions.

Journal of Organic Chemistry, 2018
The copper metalation of azomethine ylides (AYs) in [3 + 2] cycloaddition (32CA) reactions with electron-deficient ethylenes has been studied within the Molecular Electron Density Theory (MEDT) at the MPWB1K/6-311G(d,p) level, in order to shed light on ...
L. Domingo, M. Ríos‐Gutiérrez, P. Pérez   +2 more
semanticscholar   +1 more source

Concise Synthesis of Tryptanthrin Spiro Analogues with In Vitro Antitumor Activity Based on One-Pot, Three-Component 1,3-Dipolar Cycloaddition of Azomethine Ylides to Сyclopropenes

Synthesis, 2018
A simple, efficient and atom-economic method has been developed for the synthesis of complex alkaloid-like compounds with spiro-fused indolo[2,1-b]quinazoline and cyclopropa[a]pyrrolizine or 3-azabicyclo[3.1.0]hexane moieties. We have found that one-pot,
A. Filatov, N. Knyazev, S. Shmakov, A. Bogdanov, Mikhail N. Ryazantsev, A. A. Shtyrov, G. Starova, A. Molchanov, A. Larina, V. Boitsov, A. Stepakov   +10 more
semanticscholar   +1 more source

Synthesis of pyrrolizidines and indolizidines by multicomponent 1,3-dipolar cycloaddition of azomethine ylides

Pure and Applied Chemistry, 2018
Different multicomponent 1,3-dipolar cycloadditions (1,3-DC) of cyclic α-amino acid derivatives with aldehydes and dipolarophiles have been described as efficient and simple methodologies for the synthesis of the pyrrolidine unit of pyrrolizidines and ...
C. Nájera, J. Sansano
semanticscholar   +1 more source

1,3-Dipolar cycloaddition reactions of isatin-derived azomethine ylides for the synthesis of spirooxindole and indole-derived scaffolds: recent developments

Molecular diversity, 2022
Fatemeh Rostami Miankooshki, M. Bayat, Shima Nasri, Narges Habibi Samet   +3 more
semanticscholar   +1 more source