Results 61 to 70 of about 14,053 (195)

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Azoospermia Due to Functional and Partial Ejaculatory Duct Obstruction: A Rare Case Report and Literature Review

American Journal of Men's Health
Ejaculatory duct obstruction (EDO) is a rare but treatable cause of male infertility. This case report describes a 28-year-old male with obstructive azoospermia. The patient came to our hospital after a fertility check-up revealed azoospermia.
Lei Zheng, Lihong Wang, Hui Jiang, Tao Jiang   +3 more
doaj   +1 more source

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, EarlyView.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

Cell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu, Wenfeng Zhang, Xiao Jiang, Jianping Chen, Lei Zhu, Zhonghao Zhang, Jing Gu, Lulu Guo, Lin Ao, Qing Chen, Lei Sun, Yuhan Hu, Xin Wang, Yaxin Liu, Jia Cao, Fei Han, Jinyi Liu   +16 more
wiley   +1 more source

A Study on Causes of Azoospermia in Urology Clinic of Yasuj University of Medical Sciences

Armaghane Danesh Bimonthly Journal, 2006
: Introduction & Objective: Azoospermia means no sperm in semen. It may be due to hormonal imbalance, any disorder in production of sperm, or might be due to obstruction in sperm pathway from testis till ejaculatory ducts.
SMR Rabani, A Moosavizadeh
doaj  

Clinician’s guide to the management of azoospermia induced by exogenous testosterone or anabolic–androgenic steroids

Asian Journal of Andrology
Azoospermia, defined as the absence of sperm in the ejaculate, is a well-documented consequence of exogenous testosterone (ET) and anabolic–androgenic steroid (AAS) use.
Manaf Al Hashimi, Germar-Michael Pinggera, Rupin Shah, Ashok Agarwal   +3 more
doaj   +1 more source

BOLL‐Containing Aggregates Mediate the Translational Regulation During Human Oogenesis

Cell Proliferation, EarlyView.
This work elucidates that BOLL‐containing aggregate‐mediated translational control is essential for human oogenesis. These aggregates recruit PABPC1 and FXR1 to activate the translation of U‐rich mRNAs encoding cell cycle proteins, thereby ensuring successful meiotic progression.
Ying Li, Lingya Mao, Boyuan Liang, Longxin Xie, Wenpei Xiang, Kehkooi Kee   +5 more
wiley   +1 more source

The combined effects of swimming exercise and stem cell transplantation on the expression of CD9 and CD63 tetraspanin genes in a rat model of azoospermia

مجله علوم پزشکی فیض (پیوسته)
Background and Aim: Azoospermia, defined as the absence of sperm in semen, is a common cause of male infertility. This study aimed to determine the combined effects of swimming exercise and stem cell transplantation on the expression of CD9 and CD63 ...
Maziyar Shojaee, lida moradi, Parvin Farzanei, Bahram Abedi   +3 more
doaj  

Obstructive azoospermia: reconstructive techniques and results

Clinics, 2013
Obstructive azoospermia is a common cause of male infertility and can result from infection, congenital anomalies, or iatrogenic injury. Microsurgical vasal reconstruction is a suitable treatment for many cases of obstructive azoospermia, although some ...
Karen Baker, Edmund Sabanegh Jr.
doaj  

Diagnostic yield of OCT3/4 reflex testing in testicular biopsy

Histopathology, EarlyView.
GCNIS detection frequency was 48/3353 (1.4%) testicular biopsies from 42/1870 (2.2%) men who underwent testicular biopsy with or without testicular sperm extraction (TESE). OCT3/4 was particularly helpful for detecting interstitial seminoma, GCNIS coexisting with mature spermatogenesis, and focal GCNIS.
Roselyne Choiniere, Willem PA Boellaard, Geert JLH van Leenders   +2 more
wiley   +1 more source