Results 71 to 80 of about 35,229 (220)

Iqcm Is Dispensable for Male Fertility in Mice

iNew Medicine, EarlyView.
Schematic overview of the experimental workflow. Iqcm is highly expressed in mice testis (left). Iqcm−/− mice were generated via CRISPR/Cas9 (second panel). Phenotypic analyses including testis/epididymis histology (H&E), sperm morphology, and litter size revealed no significant differences between Iqcm+/+ and Iqcm−/− mice (third panel).
Zhaojuan Yu, Yuhui Ye, Mingfei Xiang, Zhaolian Wei, Zhen Lu, Jia Peng, Yunxia Cao   +6 more
wiley   +1 more source

Distribution of CFTR and IVS8polyT genotypes in the two groups of patients divided according to the histopathological results: obstructive azoospermia and nonobstructive azoospermia/oligozoospermia.

, 2014
[−] means no CF mutation detected on single chromosome.Distribution of CFTR and IVS8polyT genotypes in the two groups of patients divided according to the histopathological results: obstructive azoospermia and nonobstructive azoospermia/oligozoospermia.
Marija Mircevska (658227), Dijana Plaseska-Karanfilska (125134), Svetlana Madjunkova (658226), Vanja Filipovski (658229), Toso Plaseski (658228), Predrag Noveski (658225)   +5 more
core   +1 more source

Role of testicular fine‐needle aspiration in the modern male reproductive urologist′s practice

UroPrecision, EarlyView.
Abstract Background Azoospermia affects 10%–15% of infertile men, with non‐obstructive azoospermia (NOA) most often managed by microdissection testicular sperm extraction (mTESE). Despite AUA/ASRM guidelines recommending mTESE, some urologists employ testicular fine‐needle aspiration (TFNA) mapping as a diagnostic adjunct.
Parth Joshi, Jordan Kassab, Vivek Aslot, Richard Schoor   +3 more
wiley   +1 more source

Azoospermia after testosterone gel treatment

, 2017
A case report presented azoospermia in 30 y.o. man after 4 months of 50 mg daily dose testosterone gel treatment. The absence of sperm in ejaculate urged interruption of couple infertility treatment by means of IVF, oocytes cryopreservation was performed.
Ruslan D Zasseev, Igor A Korneyev
core   +1 more source

Prevalence of HCMV, HHV‐6, and HSV‐1/2 in the semen of men attending infertility clinics and their association with semen parameters

UroPrecision, EarlyView.
Abstract Background Viral infections have been identified as potential disruptors of male reproductive health. This study aimed to investigate the prevalence of human cytomegalovirus (HCMV), human herpesvirus 6 (HHV‐6), and herpes simplex virus types 1 and 2 (HSV‐1/2) DNA in semen samples from fertile and infertile men within the potential impact of ...
Seyedeh Zahra Hashemi, Neda Pirbonyeh, Fahime Edalat, Narges Eslami, Saeed Tajik, Arash Letafati, Jamal Sarvari, Afagh Moattari   +7 more
wiley   +1 more source

Scrotal US for evaluation of infertile men with azoospermia

, 2006
PURPOSE: To evaluate prospectively the accuracy of scrotal ultrasonography (US) in distinguishing obstructive azoospermia from nonobstructive azoospermia in infertile men by using histologic findings as the reference standard.
Cho, Jeong Yeon, Chun, Yi Kyeong, Kim, Seung Hyup, Moon, Min Hoan, Seo, Ju Tae   +4 more
core   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

First reported deliveries in Ireland using surgically retrieved sperm for non-obstructive azoospermia

, 2010
Couples presenting with male factor infertility comprise an important proportion of clinical reproductive endocrinology consultations. Indeed, a problem with the male is the only cause, or a contributing cause, of infertility in ~40% of infertility ...
Yokota, T.T., Sills, E.S., A. P. H. Walsh, B. J. Jones, T. T. Yokota, G. D. Coull, D. J. Walsh, Walsh, D.J., Walsh, A.P.H., Coull, G.D., E. S. Sills, Jones, B.J.   +11 more
core   +1 more source

Cryopreservation of Spermatozoa Prior and Post‐Orchiectomy in Patients With Testicular Germ Cell Cancer—Does the Timing Matter?

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell cancer (TGCC) is the most frequent malignancy in young men of reproductive age. According to guidelines, semen cryopreservation should be performed prior to orchiectomy. Lack of time and local facilities as well as mental pressure are challenges in terms of fertility preservation before surgery.
Yuhe Tang, Gerald Pühse, Sabine Kliesch, Jann‐Frederik Cremers, Maria Schubert   +4 more
wiley   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source