Results 61 to 70 of about 35,229 (220)

Management of the Infertile Male with Azoospermia

open access: yesDüzce Tıp Fakültesi Dergisi, 2022
Azoospermia means the complete absence of spermatozoa upon examination of the semen. Azoospermia may result from a lack of spermatozoa production in the testicles, or from an inability of produced spermatozoa to reach the emitted semen.
Erdem Akbay, Mesut Tek
doaj   +1 more source

Chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia in Eastern China

open access: yesJournal of International Medical Research, 2020
Objective The objective was to investigate the frequency and type of chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia to ensure appropriate genetic counseling before assisted reproduction in ...
Jing Sha   +5 more
doaj   +1 more source

Copy number variations (CNVs) and karyotyping analysis in males with azoospermia and oligospermia

open access: yesBMC Medical Genomics, 2023
Background Considering the essential roles that genetic factors play in azoospermia and oligospermia, this study aims to identify abnormal chromosomes using karyotyping and CNVs and elucidate the associated genes in patients.
Xing Xin   +11 more
doaj   +1 more source

Genetic Landscape of Nonobstructive Azoospermia and New Perspectives for the Clinic

open access: yesJournal of Clinical Medicine, 2020
Nonobstructive azoospermia (NOA) represents the most severe expression of male infertility, involving around 1% of the male population and 10% of infertile men. This condition is characterised by the inability of the testis to produce sperm cells, and it
M. Cerván-Martín   +3 more
semanticscholar   +1 more source

Prediction Models for Successful Sperm Retrieval in Patients with Non-Obstructive Azoospermia Undergoing Microdissection Testicular Sperm Extraction: Is There Any Room for Further Studies?

open access: yesJournal of Clinical Medicine, 2021
Several prediction models for successful sperm retrieval (SSR) in patients with azoospermia due to spermatogenic dysfunction (also termed non-obstructive azoospermia—NOA) have been developed and published in the past years, however their resulting ...
E. Caroppo, G. Colpi
semanticscholar   +1 more source

The relationship between testicular tumour characteristics and azoospermia: a systematic review

open access: yes, 2022
Subfertility is a risk factor for testicular cancers (TT), and conversely, TT may induce subfertility due to local and regional toxic effects. We aimed to identify the association between TT characteristics and pre-orchidectomy azoospermia.
Alnajjar, Hussain M.   +3 more
core   +1 more source

A new TEX11 mutation causes azoospermia and testicular meiotic arrest

open access: yesAsian Journal of Andrology, 2021
There are many unknown genetic factors that lead to infertility in nonobstructive azoospermia men. Here, we performed whole-exome sequencing in blood samples obtained from 40 azoospermia patients with meiotic arrest and found a novel c.151_154del (p ...
Xiaochen Yu   +5 more
semanticscholar   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

open access: yesAdvanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian   +14 more
wiley   +1 more source

The importance of semen analysis in the context of azoospermia

open access: yes, 2012
Azoospermia is a descriptive term referring to ejaculates that lack spermatozoa without implying a specific underlying cause. The traditional definition of azoospermia is ambiguous, which has ramifications on the diagnostic criteria.
Nabil Aziz, Aziz, Nabil
core   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

open access: yesAnimal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang   +11 more
wiley   +1 more source

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