Results 61 to 70 of about 28,616 (239)

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

Algorithms for Predicting the Probability of Azoospermia from Follicle Stimulating Hormone: Design and Multi-Institutional External Validation

open access: yesThe World Journal of Men's Health, 2022
Purpose: To predict the probability of azoospermia without a semen analysis in men presenting with infertility by developing an azoospermia prediction model. Materials and Methods: Two predictive algorithms were generated, one with follicle stimulating
Michael B. Tradewell   +10 more
doaj   +1 more source

Clinical case seminar - Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita [PDF]

open access: yes, 2002
Mutations in the orphan nuclear receptor DAX-1 cause X-linked adrenal hypoplasia congenita. Affected boys usually present with primary adrenal failure in early infancy or childhood.
Achermann, JC   +8 more
core  

Serum inhibin B as a marker of spermatogenesis [PDF]

open access: yes, 1998
Inhibin B is produced by Sertoli cells, provides negative feedback on FSH secretion, and may prove to be an important marker for the functioning of seminiferous tubules.
Jong, F.H. (Frank) de   +4 more
core   +4 more sources

Development of a nomogram for sperm retrieval at microTESE for idiopathic non‐obstructive azoospermia in a multi‐center cohort study

open access: yesAndrology, EarlyView.
Abstract Background Non‐obstructive azoospermia (NOA) affects approximately 10% of infertile men and represents a major challenge in assisted reproductive technology (ART). A model that includes histological variants could be helpful in predicting sperm retrieval rate (SRR) after microdissection testicular sperm extraction (mTESE) in patients affected ...
Giorgio Ivan Russo   +10 more
wiley   +1 more source

TXNDC2 joint molecular marker is associated with testis pathology and is an accurate predictor of sperm retrieval

open access: yesScientific Reports, 2021
The association of PRM1/2 with male azoospermia is well-documented, but the relationship between TXNDC2 deficiency and the azoospermia phenotype, sperm retrieval, and pathology has not been elucidated.
Seyed-Morteza Javadirad   +1 more
doaj   +1 more source

Infertility and hypergonadotropic hypogonadism as first evidence of hereditary apolipoprotein A-I amyloidosis [PDF]

open access: yes, 2007
Purpose: We report that primary infertility and hypergonadotropic hypogonadism in young patients may be caused by testicular amyloidosis and it is associated with the presence of a mutation in the apoA-I gene, resulting in the replacement of proline for ...
BIASI L   +7 more
core   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

open access: yesAndrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu   +8 more
wiley   +1 more source

Cryopreservation of Spermatozoa Prior and Post‐Orchiectomy in Patients With Testicular Germ Cell Cancer—Does the Timing Matter?

open access: yesAndrology, EarlyView.
ABSTRACT Background Testicular germ cell cancer (TGCC) is the most frequent malignancy in young men of reproductive age. According to guidelines, semen cryopreservation should be performed prior to orchiectomy. Lack of time and local facilities as well as mental pressure are challenges in terms of fertility preservation before surgery.
Yuhe Tang   +4 more
wiley   +1 more source

A case of azoospermia in a non-destructive testing worker exposed to radiation

open access: yesAnnals of Occupational and Environmental Medicine, 2017
Background Interest in radiation-related health problems has been growing with the increase in the number of workers in radiation-related jobs. Although an occupational level of radiation exposure would not likely cause azoospermia, several studies have ...
Jaechan Park   +3 more
doaj   +1 more source

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