Results 111 to 120 of about 15,583 (213)

Azoxymethane誘発大腸腫瘍発生に対するBio-three (Streptococcus faecalis， Bacillus ntesentericus， Clostridium butyricum)経口投与の抑制効果 [PDF]

, 1991
今回，整腸作用を有し乳酸菌等を腸内で増殖させる3種菌株(streptococcus faecalis， Bacillus mesentericus， Clostridium butyricum) のAzoxymethane (A0M)誘発大腸腫瘍に対する効果を検討した結果，AOM(7.4mg/kg S.C.
坂本 憲市, 山本 克弥, 田沢 賢次, 藤巻 雅夫   +3 more
core   +1 more source

Heme iron amplifies azoxymethane initiating effect on rat colon preneoplastic lesions

Redox Experimental Medicine
Objective: Colorectal cancer is a major public health issue for which dietary factors such as red and processed meat consumption seem to play a prominent role. Heme iron, which is present in important concentration in those food products, was reported to
Julia Keller, Pascale Plaisancié, Edwin Fouché, Edwige-Marie Pralet, Nathalie Naud, Florence Blas-Y-Estrada, Claire Maslo, Ingrid Ahn, Sylvie Chevolleau, Maria-Helena Meireles, Cécile Héliès-Toussaint, Sylvia Pietri, Mathieu Cassien, Laure Khoury, Marc Audebert, Fabrice Pierre, Vassilia Theodorou, Maïwenn Olier, Françoise Guéraud   +18 more
doaj   +1 more source

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. [PDF]

, 2020
Copper levels are known to be elevated in inflamed and malignant tissues. But the mechanism underlying this selective enrichment has been elusive. In this study, we report a axis by which inflammatory cytokines, such as IL-17, drive cellular copper ...
Bao, Shideng, Bulek, Katarzyna, Cai, Gang, Chang, Christopher J, Chen, Xing, Fox, Paul L, Huang, Emina, Jackson, Mark W, Jia, Shang, Kalady, Matthew F, Li, Xiaoxia, Liao, Yun, Pizarro, Theresa T, Sen, Ganes C, Stark, George R, Tang, Fangqiang, Zhao, Junjie   +16 more
core  

Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model [PDF]

, 2013
The protection against colorectal cancer (CRC) by non-steroidal anti-inflammatory drugs (NSAIDs) is in part dependent on inhibition of cyclooxygenase (COX).
Hu, Ying, Le Leu, Richard Kevin, Martin, Jonathan Edward, Young, Graeme Paul   +3 more
core  

Repercussão hepática da carcinogênese colorretal induzida pelo azoximetano Hepatic repercussions of azoxymethane-induced colorectal carcinogenesis

Revista do Colégio Brasileiro de Cirurgiões, 2013
OBJETIVO: Avaliar as repercussões hepáticas da carcinogênese colônica induzida por diferentes doses e tempos de exposição ao azoximetano em ratos Wistar. MÉTODOS: Quarenta e quatro ratos foram distribuídos em quatro grupos. Os animais tinham oito semanas
Idália Maria Brasil Burlamaqui, Conceição Aparecida Dornelas, Paulo Roberto Carvalho Almeida, Francisco Vagnaldo Fechine Jamacaru, Daniel Magalhães Coutinho Mota, Francisco José Cabral Mesquita, Lara Albuquerque de Brito, Lara Burlamaqui Veras, Lusmar Veras Rodrigues   +8 more
doaj  

Wild cherry (Prunus microcarpa) ameliorates azoxymethane-induced aberrant crypt foci in vivo: Depicted molecular mechanisms

ARO-The Scientific Journal of Koya University
Colorectal cancer is the third diagnosed cancer across the globe despite modern therapeutic interventions. Prunus microcarpa has been consumed as a therapeutic tea for several human disorders; therefore, the study investigates the chemoprotective ...
Ahmed A. Abduljabbar, Parween A. Ismail
doaj   +1 more source

Evaluation of Nanocarrier Targeted Drug Delivery of Capecitabine-PAMAM Dendrimer Complex in a Mice Colorectal Cancer Model

Acta Medica Iranica, 2016
Capecitabine, an effective anticancer drug in colorectal cancer chemotherapy, may create adverse side effects on healthy tissues. In the present study, we first induced colon adenocarcinoma with azoxymethane, a carcinogen agent, and then investigated the
Fatemeh Nabavizadeh, Hafseh Fanaei, Alireza Imani, Jalal Vahedian, Fahimeh Asadi Amoli, Jamal Ghorbi, Hamid Sohanaki, Seyed Mehdi Mohammadi, Ravieh Golchoobian   +8 more
doaj  

Morphometric investigation of the effects of Azoxymethane, Diallyl disulfide and corn oil use on humerus and femur development in rats

Revista Científica
The study aimed to examine the effects of Azoxymethane (AOM), Diallyl Disulfide (DADS), and corn oil on the humerus and femur in rats. In the study, 40 male Wistar Albino rats, 12 weeks old, were used. The animals were divided into four different groups
Sedat Aydoğdu
doaj   +1 more source

Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat’s colon by augmentation of apoptotic proteins and antioxidant mechanisms

Scientific Reports
Mangiferin (MF) is a natural C-glucosylxantone compound that has many substantial curative potentials against numerous illnesses including cancers.
Khaled Abdul-Aziz Ahmed, Ahmed A. J. Jabbar, Mahmood Ameen Abdulla, Zaenah Zuhair Alamri, Nur Ain Salehen, Ibrahim Abdel Aziz Ibrahim, Ghassan Almaimani, Ghazi A. Bamagous, Riyad A. Almaimani, Hussain A. Almasmoum, Mazen M. Ghaith, Wesam F. Farrash   +11 more
doaj   +1 more source

Effect of Garambullo (Myrtillocactus geometrizans) Consumption on the Intestinal Microbiota Profile in an Early-Phase Rat Model of Colon Cancer. [PDF]

Int J Mol Sci
Sánchez-Recillas E, Almanza-Aguilera E, Bars-Cortina D, Zamora-Ros R, Godínez-Santillán RI, Sánchez-Tusié AA, Vergara-Castañeda HA.   +6 more
europepmc   +1 more source