Results 1 to 10 of about 809,759 (252)

Utilizing Sphingomyelinase Sensitizing Liposomes in Imaging Intestinal Inflammation in Dextran Sulfate Sodium-Induced Murine Colitis [PDF]

open access: yesBiomedicines, 2022
Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal tract, resulting in severe symptoms. At the moment, the goal of medical treatments is to reduce inflammation. IBD is treated with systemic anti-inflammatory
Tuula Penate Medina   +7 more
doaj   +2 more sources

Expanding the utility of the dextran sulfate sodium (DSS) mouse model to induce a clinically relevant loss of intestinal barrier function [PDF]

open access: yesPeerJ, 2020
Background Inflammatory bowel disease (IBD) is a family of debilitating disorders that affects more than 1 million people in the United States. Many animal studies of IBD use a dextran sulfate sodium (DSS) mouse model of colitis that induces rapid and ...
Kyle E. Cochran   +2 more
doaj   +2 more sources

Dextran sodium sulfate (DSS) induces colitis in mice by forming nano-lipocomplexes with medium-chain-length fatty acids in the colon. [PDF]

open access: yesPLoS ONE, 2012
Inflammatory bowel diseases (IBDs), primarily ulcerative colitis and Crohn's disease, are inflammatory disorders caused by multiple factors. Research on IBD has often used the dextran sodium sulfate (DSS)-induced colitis mouse model.
Hamed Laroui   +9 more
doaj   +1 more source

Calycosin attenuates dextran sulfate sodium (DSS)-induced experimental colitis [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s):Inflammatory bowel disease (IBD) results from dysregulation of intestinal mucosal immunity. It is an incurable disease that affects millions of people worldwide.
Liu Chao   +6 more
doaj   +1 more source

Blackcurrant Alleviates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice

open access: yesFoods, 2023
Previous studies have reported that anthocyanin (ACN)-rich materials have beneficial effects on ulcerative colitis (UC). Blackcurrant (BC) has been known as one of the foods rich in ACN, while studies demonstrating its effect on UC are rare.
Hye-Jung Moon   +2 more
doaj   +1 more source

Protection Against Dextran Sulfate Sodium-Induced Ulcerative Colitis In Mice By Neferine, A Natural Product From Nelumbo Nucifera Gaertn [PDF]

open access: yesCell Journal, 2021
Objective: Ulcerative colitis (UC) is a long-lasting inflammatory disease of the colon. Epidemiological studies showed that the prevalence and incidence of UC are increasing worldwide in recent years. Neferine is a natural alkaloid isolated from Nelumbo
Xiangjing Min   +3 more
doaj   +1 more source

CU06-1004 Alleviates Experimental Colitis by Modulating Colonic Vessel Dysfunction

open access: yesFrontiers in Pharmacology, 2020
Inflammatory bowel disease is an autoimmune disease that causes chronic inflammation of the gastrointestinal tract. Endothelial dysfunction, defined by a reduced endothelial barrier and an increase in the expression of adhesion molecules, is part of the ...
Ye-Seul Kim   +6 more
doaj   +1 more source

Minimally invasive in vivo endoscopic monitoring of dextran sulfate sodium-induced murine colitis

open access: yesMethodsX, 2022
Ulcerative colitis (UC) is a gastrointestinal, autoimmune disease that causes ulceration and inflammation of the colon with an incidence of 10 out of every 100,000 people in North America and Western Europe.
Elizabeth A. Bullard   +4 more
doaj   +1 more source

Dextran Sulfate Sodium Salt-Induced Colitis Aggravates Gut Microbiota Dysbiosis and Liver Injury in Mice With Non-alcoholic Steatohepatitis

open access: yesFrontiers in Microbiology, 2021
Objective: Inflammatory bowel disease (IBD) is characterized by gut microbiota dysbiosis, which is also frequently observed in patients with non-alcoholic fatty liver disease.
Bo Shen   +25 more
doaj   +1 more source

Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

open access: yesPharmaceuticals, 2021
Epidemiological studies have indicated that obesity is an independent risk factor for colitis and that a high-fat diet (HFD) increases the deterioration of colitis-related indicators in mice.
Shijia Pan   +7 more
doaj   +1 more source

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