Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: Neuroinflammation in the gut is associated with many gastrointestinal (GI) diseases, including inflammatory bowel disease. In the brain, neuroinflammatory conditions are associated with blood-brain barrier (BBB) disruption and ...
David Dora +10 more
doaj +1 more source
Gut modulation of dysbiosis induced by dextran sulfate sodium
Food Bioscience, 2021 Abstract Inflammatory bowel disease is one of the serious burdens of clinical medicine and healthcare. This study investigated the potential of a biological product based on mare's milk and metabolites of symbiotic microflora for modulation of intestinal microflora affected by dextran sulfate sodium (DSS)-induced dysbiosis.
Samat Kozhakhmetov +12 more
openaire +1 more source
Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2 0-deoxyguanosine, in rat colonic mucosa [PDF]
, 1998 Dextran sodium sulfate (DSS) given in drinking water can induce colonic Inflammation and produce colorectal tumors in rodents, although it is not directly genotoxic.
Petit, Claude +5 more
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Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Green Soybean Extract Ameliorates Dextran Sodium Sulfate-Induced Colitis
Natural Product Communications, 2018 Green-mature soybean ( Glycine max ) extract (GSE) inhibits the progression of immunoglobulin E-mediated inflammation more than the ordinary yellow-pigmented soybean extract (YSE).
Yuko Yoshikawa +6 more
doaj +1 more source
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis
Scientific Reports, 2021 FXR is a member of the nuclear receptor superfamily and bile acids are endogenous ligands of FXR. FXR activation has recently been reported to inhibit intestinal inflammation and tumour development.
Tsuneyuki Miyazaki +13 more
doaj +1 more source
Stabilization of low-cost phase change materials for thermal energy storage applications
iScience, 2023 Summary: Sodium sulfate decahydrate (Na2SO4.10H2O, SSD), a low-cost phase change material (PCM), can store thermal energy. However, phase separation and unstable energy storage capacity (ESC) limit its use.
Damilola O. Akamo +10 more
doaj +1 more source
Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases [PDF]
BMC Immunology, 2012 Abstract Background Inflammatory bowel diseases (IBDs) are chronic, relapsing disorders that affect the gastrointestinal tract of millions of people and continue to increase in incidence each year. While several factors have been associated with development of IBDs, the exact etiology is unknown. Research using animal
Rose William A +2 more
openaire +3 more sources
Carbon 60 Dissolved in Grapeseed Oil Inhibits Dextran Sodium Sulfate-Induced Experimental Colitis
, 2022 Rayko Lazcano-Silveira,1 Xiaoxiao Jia,1 Kaixuan Liu,2 Honggang Liu,2 Xinrong Li,2 Mizhou Hui1 1College of Life Sciences, Northeast Agricultural University, Harbin, Heilongjiang, People’s Republic of China; 2College of Animal Science and Technology ...
Liu H +5 more
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