Results 31 to 40 of about 98,592 (289)
Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development
Nature Communications, 2023 Chronic colonic inflammation is a feature of cancer and is strongly associated with tumorigenesis, but its underlying molecular mechanisms remain poorly understood.
Mingyu Lee +10 more
doaj +1 more source
Osteopontin attenuation of dextran sulfate sodium-induced colitis in mice [PDF]
Laboratory Investigation, 2009 Osteopontin (OPN) is a matricellular cytokine present in most tissues and body fluids; it is known to modulate immune responses. In previous studies using the dextran sulfate sodium (DSS) acute colitis model, we found exacerbated tissue destruction and reduced repair in OPN-null ((-/-)) mice compared with wild-type (WT) controls.
da Silva, Andre Paes Batista +5 more
openaire +5 more sources
Vimentin Suppresses Inflammation and Tumorigenesis in the Mouse Intestine
Frontiers in Cell and Developmental Biology, 2022 Vimentin has been implicated in wound healing, inflammation, and cancer, but its functional contribution to intestinal diseases is poorly understood.
Linglu Wang +16 more
doaj +1 more source
Evidence for the role of proteoglycans in cation-mediated gene transfer [PDF]
, 1996 We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated proteoglycans. Treatment of HeLa cells with sodium chlorate, a potent inhibitor of proteoglycan sulfation, reduced luciferase
Baldeschwieler, John D. +1 more
core +1 more source
PATOFISIOLOGI KOLITIS YANG DIINDUKSI DEXTRAN SODIUM SULFAT
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara, 2021 Penyakit Radang Usus atau Intestinal Bowel Diseases (IBD) terutama terdiri dari Kolitis Ulserativa dan penyakit Crohn merupakan penyakit kompleks hasil dari respon imun kronis yang tidak teratur di saluran pencernaan dan multifaktorial dengan etiologi pastinya tidak diketahui. Untuk menyelidiki patogenesis dan etiologi IBD manusia, berbagai hewan model
openaire +1 more source
Permselectivity of the glomerular wall examined with iron compound tracer [PDF]
, 1977 Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary.
Hirata, Kooiti
core +1 more source
Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice
Journal of Agricultural and Food Chemistry, 2021 Screening potential compounds for improving ulcerative colitis (UC) from clinical medication is an effective strategy for drug repurposing. We applied bioinformatics and network pharmacology to the drug screening process in this study, which helped us to screen out troxerutin that could improve UC.
Xingqi Wang +14 more
openaire +3 more sources
Journal of Dairy Science, 2022 : Camel milk is a nutritionally rich food that shows anti-inflammatory, immune regulation, and gut microbiota maintenance properties. However, the relationship between camel milk and the intestinal microbiota during colitis is unclear.
Jing He +4 more
doaj +1 more source
The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels [PDF]
, 2013 Aim: Topical administration of siRNA nanocarriers is a promising approach in the treatment of pulmonary disorders. Pulmonary surfactant, covering the entire alveolar surface of mammalian lungs, will be one of the first interfaces that siRNA nanocarriers ...
Braeckmans, Kevin +4 more
core +1 more source
Purification of Total RNA from DSS-treated Murine Tissue via Lithium Chloride Precipitation
Bio-Protocol, 2018 We have developed a protocol to purify RNA from DSS (Dextran Sulfate Sodium)-treated mouse tissues. This method, which prevents downstream inhibition of q-RT-PCR observed in DSS-treated tissues, relies on successive precipitations with lithium chloride.
Emilie Viennois +2 more
doaj +1 more source