Results 31 to 40 of about 64,315 (292)
Pathogenic mechanisms responsible for inflammatory bowel disease (IBD) are poorly understood. In an IBD animal model, the oral administration of polysaccharides such as dextran sulfate sodium (DSS) induces colitis, which exhibit several clinical and histological features for IBD. However, pathogenic factors in the development of colitis remain unclear.
Yoshio, Araki +2 more
openaire +3 more sources
: Camel milk is a nutritionally rich food that shows anti-inflammatory, immune regulation, and gut microbiota maintenance properties. However, the relationship between camel milk and the intestinal microbiota during colitis is unclear.
Jing He +4 more
doaj +1 more source
Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors [PDF]
Background: Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation due to dysregulation of the mucosal immune system.
Schnurr, M. +9 more
core +1 more source
Purification of Total RNA from DSS-treated Murine Tissue via Lithium Chloride Precipitation
We have developed a protocol to purify RNA from DSS (Dextran Sulfate Sodium)-treated mouse tissues. This method, which prevents downstream inhibition of q-RT-PCR observed in DSS-treated tissues, relies on successive precipitations with lithium chloride.
Emilie Viennois +2 more
doaj +1 more source
Lithium induces intestinothrophic effects in the healthy colon, but does not ameliorate dextran sulfate sodium-induced colitis in mice [PDF]
Background & aims: Ulcerative colitis is characterized by severe damage of the colon epithelium. Wnt-signaling is important for repair and regeneration of the intestinal epithelium.
Blokzijl, Tjasso +8 more
core +1 more source
Dextran Sodium Sulfate-induced Colitis as a Model for Sarcopenia in Mice [PDF]
Forty-two percent of inflammatory bowel disease patients suffer from sarcopenia. We established a mouse model for this condition. Dextran sodium sulfate–induced colitis caused a severe decrease in muscle mass, fiber size, and the regulation of sarcopenia-associated key players on mRNA level.
Dominik Saul, Robyn Laura Kosinsky
openaire +3 more sources
The application of sodium dextran sulfate to the field of cosmetics
In this study, it was shown that sodium dextran sulfate (DS), which is used as an antihyperlipoproteinemic and is clinically known for the improvement of the blood flow, accelerated nitric oxide (NO) synthesis in the normal human epidermal keratinocytes.
openaire +2 more sources
Promising anti-diabetic effect of dextran sulfate sodium: Is it its clinical come back? [PDF]
Clinical studies showed that dextran sulfate sodium (DSS) alleviates stroke, diabetic retinopathy and hypercholesterolemia, yet its mechanism of action was unrevealed.
Noureldein, Mohamed H. +3 more
core +1 more source
Ulcerative colitis (UC), with a long course and repeated attack, severely affects patient's life quality and increases economic burden all over the world. However, the concrete causes and mechanisms of UC are still unclear, but it is generally considered
Shiying Wang (5179559) +8 more
core +1 more source
Lack of Adrenomedullin Results in Microbiota Changes and Aggravates Azoxymethane and Dextran Sulfate Sodium-Induced Colitis in Mice [PDF]
The link between intestinal inflammation, microbiota, and colorectal cancer (CRC) is intriguing and the potential underlying mechanisms remain unknown.
Alfredo Martínez +18 more
core +1 more source

