Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development
Nature Communications, 2023 Chronic colonic inflammation is a feature of cancer and is strongly associated with tumorigenesis, but its underlying molecular mechanisms remain poorly understood.
Mingyu Lee +10 more
doaj +1 more source
Vimentin Suppresses Inflammation and Tumorigenesis in the Mouse Intestine
Frontiers in Cell and Developmental Biology, 2022 Vimentin has been implicated in wound healing, inflammation, and cancer, but its functional contribution to intestinal diseases is poorly understood.
Linglu Wang +16 more
doaj +1 more source
On the dynamics of nitrite, nitrate and other biomarkers of nitric oxide production in inflammatory bowel disease [PDF]
, 2010 Nitrite and nitrate are frequently used surrogate markers of nitric oxide (NO) production. Using rat models of acute and chronic DSS-induced colitis we examined the applicability of these and other NO-related metabolites, in tissues and blood, for the ...
Fumito Saijo +19 more
core +1 more source
The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.
, 2023 The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.
Jinhua Tian (5655472) +8 more
core +1 more source
TDAG51 deficiency attenuates dextran sulfate sodium-induced colitis in mice
Scientific Reports, 2022 Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, is a group of chronic inflammatory diseases of the gastrointestinal tract.
Hyoeun Jeon +5 more
doaj +1 more source
Dextran sulfate activates contact system and mediates arterial hypotension via B2 kinin receptors [PDF]
, 1994 To define some of the mechanisms underlying dextran sulfate (DXS)-induced hypotension, we investigated the effects of either the plasma kallikrein inhibitor des-Pro2-[Arg15] aprotinin (BAY x 4620) or the specific bradykinin B2-receptor antagonist Hoe-140
Siebeck, Matthias +7 more
core +2 more sources
Purification of Total RNA from DSS-treated Murine Tissue via Lithium Chloride Precipitation
Bio-Protocol, 2018 We have developed a protocol to purify RNA from DSS (Dextran Sulfate Sodium)-treated mouse tissues. This method, which prevents downstream inhibition of q-RT-PCR observed in DSS-treated tissues, relies on successive precipitations with lithium chloride.
Emilie Viennois +2 more
doaj +1 more source
Journal of Dairy Science, 2022 : Camel milk is a nutritionally rich food that shows anti-inflammatory, immune regulation, and gut microbiota maintenance properties. However, the relationship between camel milk and the intestinal microbiota during colitis is unclear.
Jing He +4 more
doaj +1 more source
Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors [PDF]
, 2012 Background: Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation due to dysregulation of the mucosal immune system.
Schnurr, M. +9 more
core +1 more source
Uridine Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice
Scientific Reports, 2017 Uridine, one of the four components that comprise RNA, has attracted attention as a novel therapeutic modulator of inflammation. However, very little is known about its effect on intestinal inflammation.
Manish Kumar Jeengar +4 more
doaj +1 more source