Results 11 to 20 of about 64,315 (292)

Murine Colitis Modeling using Dextran Sulfate Sodium (DSS) [PDF]

Journal of Visualized Experiments, 2010
Colitis can occur from viral or bacterial infections, ischemic insult, or autoimmune disorders; most notably Ulcerative Colitis and the colonic variant of Crohn's Disease - Crohn's Colitis. Acute colitis may present with abdominal pain and distention, malabsorption, diarrhea, hematochezia and mucus in the stool.
Whittem, Caitlyn G., Williams, Amanda D., Williams, Christopher S.   +2 more
openaire   +3 more sources

Tanshinone IIA ameliorates dextran sulfate sodium-induced inflammatory bowel disease via the pregnane X receptor

Drug Design, Development and Therapy, 2015
Xianxie Zhang,1 Yuguang Wang,2 Zengchun Ma,2 Qiande Liang,2 Xianglin Tang,2 Donghua Hu,2 Hongling Tan,2 Chengrong Xiao,2 Yue Gao2 1Air Force General Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 2Department of ...
Zhang X, Wang Y, Ma Z, Liang Q, Tang X, Hu D, Tan H, Xiao C, Gao Y   +8 more
doaj   +1 more source

Over-Expression of CD200 Protects Mice from Dextran Sodium Sulfate Induced Colitis. [PDF]

PLoS ONE, 2016
CD200:CD200 receptor (CD200R) interactions lead to potent immunosuppression and inhibition of autoimmune inflammation. We investigated the effect of "knockout"of CD200 or CD200R, or over-expression of CD200, on susceptibility to dextran sodium sulfate ...
Zhiqi Chen, Kai Yu, Fang Zhu, Reginald Gorczynski   +3 more
doaj   +2 more sources

Alloferon Alleviates Dextran Sulfate Sodium-induced Colitis [PDF]

Immune Network, 2015
Dysfunction of gut immune regulation is involved in mucosal damage in inflammatory bowel disease (IBD). However, there is still no efficacious immune-regulator for the treatment of IBD. Alloferon is a novel immune-modulatory peptide that was originally isolated from infected insects.
Kim, Hyemin, Im, Jong Pil, Kim, Joo Sung, Kang, Jae Seung, Lee, Wang Jae   +4 more
openaire   +2 more sources

Dextran-Sulfate-Sodium-Induced Colitis-Ameliorating Effect of Aqueous Phyllanthus emblica L. Extract through Regulating Colonic Cell Gene Expression and Gut Microbiomes

, 2023
The anti-inflammation effect of aqueous Phyllanthus emblica L. extract (APE) and its possible underlying mechanism in dextran sulfate sodium (DSS)-induced mice chronic colonic inflammation were studied.
Xiaoqing Li (186909), Guo Liu (448433), Wen Ouyang (484179), Xinan Peng, Zhuming Ye, Zhuming Ye (15366061), Yong Cao, Yiqi Jiang, Qianru Lin, Hao Hu, Wen Ouyang, Yigang Yu, Guo Liu, Xinan Peng (3488072), Yigang Yu (10530766), Xiaoqing Li, Qianru Lin (4089682), Yong Cao (9208), Yiqi Jiang (3580811), Hao Hu (111737)   +19 more
core   +1 more source

CU06-1004 Alleviates Experimental Colitis by Modulating Colonic Vessel Dysfunction

Frontiers in Pharmacology, 2020
Inflammatory bowel disease is an autoimmune disease that causes chronic inflammation of the gastrointestinal tract. Endothelial dysfunction, defined by a reduced endothelial barrier and an increase in the expression of adhesion molecules, is part of the ...
Ye-Seul Kim, Haiying Zhang, Sunghye Lee, Songyi Park, Minyoung Noh, Young-Myeong Kim, Young-Guen Kwon   +6 more
doaj   +1 more source

Osteopontin attenuation of dextran sulfate sodium-induced colitis in mice [PDF]

Laboratory Investigation, 2009
Osteopontin (OPN) is a matricellular cytokine present in most tissues and body fluids; it is known to modulate immune responses. In previous studies using the dextran sulfate sodium (DSS) acute colitis model, we found exacerbated tissue destruction and reduced repair in OPN-null ((-/-)) mice compared with wild-type (WT) controls.
da Silva, Andre Paes Batista, Ellen, Richard P., Sørensen, Esben S., Goldberg, Harvey A., Zohar, Ron, Sodek, Jaro   +5 more
openaire   +5 more sources

Minimally invasive in vivo endoscopic monitoring of dextran sulfate sodium-induced murine colitis

MethodsX, 2022
Ulcerative colitis (UC) is a gastrointestinal, autoimmune disease that causes ulceration and inflammation of the colon with an incidence of 10 out of every 100,000 people in North America and Western Europe.
Elizabeth A. Bullard, Ariel I. Mundo, Shelby N. Bess, Kathryn Miller Priest, Timothy J. Muldoon   +4 more
doaj   +1 more source

Dextran Sulfate Sodium Salt-Induced Colitis Aggravates Gut Microbiota Dysbiosis and Liver Injury in Mice With Non-alcoholic Steatohepatitis

Frontiers in Microbiology, 2021
Objective: Inflammatory bowel disease (IBD) is characterized by gut microbiota dysbiosis, which is also frequently observed in patients with non-alcoholic fatty liver disease.
Bo Shen, Bo Shen, Junjun Wang, Junjun Wang, Yuecheng Guo, Yuecheng Guo, Tianyi Gu, Tianyi Gu, Zhenyang Shen, Zhenyang Shen, Cui Zhou, Cui Zhou, Binghang Li, Binghang Li, Xianjun Xu, Xianjun Xu, Fei Li, Fei Li, Qidi Zhang, Qidi Zhang, Xiaobo Cai, Xiaobo Cai, Hui Dong, Hui Dong, Lungen Lu, Lungen Lu   +25 more
doaj   +1 more source

Protection Against Dextran Sulfate Sodium-Induced Ulcerative Colitis In Mice By Neferine, A Natural Product From Nelumbo Nucifera Gaertn [PDF]

Cell Journal, 2021
Objective: Ulcerative colitis (UC) is a long-lasting inflammatory disease of the colon. Epidemiological studies showed that the prevalence and incidence of UC are increasing worldwide in recent years. Neferine is a natural alkaloid isolated from Nelumbo
Xiangjing Min, Yanling Guo, Yishan Zhou, Xiuping Chen   +3 more
doaj   +1 more source