Results 61 to 70 of about 64,315 (292)

Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation

, 2020
Ceramide synthase 5 is one of six enzymes that catalyze the production of ceramides from sphingosine or sphinganine. Ceramides are important components of cell membranes and act as signaling molecules.
Dominique Thomas, Sebastian Brachtendorf, Stephanie Oertel, Kerstin Birod, Khadija El-Hindi, Sandra Trautmann, Jennifer Christina Hartel, Olaf Utermöhlen, Thomas Ulshöfer, Andreas Weigert, Martin Krönke, Sabine Grösch   +11 more
core   +2 more sources

β-ionone prevents dextran sulfate sodium-induced ulcerative colitis and modulates gut microbiota in mice

Food Innovation and Advances
β-ionone has various biological activities, such as anti-inflammatory, antimicrobial, and anticancer effects. The pathogenesis of ulcerative colitis is correlated with immune dysfunction, intestinal barrier damage, and gut microbiota imbalance.
Jingjing Fang, Tingting Liu, Yumeng Wang, Seong-Gook Kang, Kunlun Huang, Tao Tong   +5 more
doaj   +1 more source

Improving Effects of Epigallocatechin-3-gallate (EGCG) on Dextran Sulfate Sodium (DSS)-Induced Colitis

Shipin gongye ke-ji, 2023
This study aimed to investigate the effect of epigallocatechin-3-gallate (EGCG) on dextran sulfate sodium (DSS)-induced colitis and gut microbiota in mice.
Jie LI, Zhixu ZHANG
doaj   +1 more source

Flowchart of dextran sulfate sodium (DSS) induction of colitis in mice.

, 2018
Flowchart of dextran sulfate sodium (DSS) induction of colitis in mice.
Zwe-Ling Kong (790856), Yuan-Hua Hsu (5824301), Sabri Sudirman (5824298), Jia-Ling He (5824304)   +3 more
core   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Oxysterol-mediated modulation of intestinal inflammation: insights into sex differences and GPR183 signaling

Cellular and Molecular Life Sciences
Background and aims Oxysterols, oxidized derivatives of cholesterol, play complex roles in inflammatory processes, but their specific functions in inflammatory bowel diseases remain incompletely understood.
Hafsa Ameraoui, Joan Bestard-Escalas, Martin Roumain, Adam Laghouati, Pauline Bottemanne, Mireille Alhouayek, Giulio G. Muccioli   +6 more
doaj   +1 more source

The Influence of Ghrelin on the Development of Dextran Sodium Sulfate-Induced Colitis in Rats [PDF]

BioMed Research International, 2015
Ghrelin has protective and therapeutic effects in the gut. The aim of present studies was to investigate the effect of treatment with ghrelin on the development of colitis evoked by dextran sodium sulfate (DSS). Methods. Studies have been performed on rats. Colitis was induced by adding 5% DSS to the drinking water for 5 days.
Matuszyk, Aleksandra, Ceranowicz, Dagmara, Warzecha, Zygmunt, Ceranowicz, Piotr, Fyderek, Krzysztof, Gałązka, Krystyna, Cieszkowski, Jakub, Bonior, Joanna, Jaworek, Jolanta, Pihut, Małgorzata, Dembiński, Artur   +10 more
openaire   +3 more sources

Comparison of the new OPS Imaging technique with intravital microscopy: Analysis of the colon microcirculation [PDF]

, 2002
Background. The OPS imaging technique has been introduced for in vivo assessment of microcirculation in humans. The aim of this study was to validate the new technique against intravital fluorescence microscopy (IFM) for the visualization of colon ...
Langer, S., Biberthaler, Peter
core   +1 more source

Sasa quelpaertensis leaf extract suppresses dextran sulfate sodium-induced colitis in mice by inhibiting the proinflammatory mediators and mitogen-activated protein kinase phosphorylation

, 2021
Anti-inflammation; Dextran sulfate sodium; Mice; Sasa quelpaertensis Nakai leaf extract; Ulcerative ...
김유리
core   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source