Results 71 to 80 of about 64,315 (292)
Protective role of TIGAR in dextran sulfate sodium-induced colitis
徐州医科大学学报Objective To investigate the effect of TP53-induced glycolysis and apoptosis regulator (TIGAR) gene deletion on dextran sulfate sodium (DSS)-induced colitis in mice and its potential mechanisms.
TU Daman, LI Mei
doaj +1 more source
Microplastic effects on mouse colon in normal and colitis conditions: A literature review [PDF]
PeerJBackground Taking into account the global spread of microplastic (MP) pollution, the problem of the MP impact on human health is relevant. MP enters the organism predominantly with water and food, and is mostly detected in the large intestine. Therefore,
Natalia Zolotova +5 more
doaj +2 more sources
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, Volume 13, Issue 37, 3 July 2026.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Succinate-treated macrophages attenuate dextran sodium sulfate colitis in mice [PDF]
Intestinal Research, 2021 I Seul Park +6 more
doaj +1 more source
Dextran sodium sulfate (DSS) induces necrotizing enterocolitis-like lesions in neonatal mice. [PDF]
PLoS ONE, 2017 Necrotizing enterocolitis (NEC) is an inflammatory bowel disease of preterm human newborns with yet unresolved etiology. An established neonatal murine model for NEC employs oral administration of lipopolysaccharides (LPS) combined with hypoxia ...
Marco Ginzel +14 more
doaj +1 more source
Baicalein Inhibits Dextran Sulfate Sodium-induced Mouse Colitis
Journal of Cancer Prevention, 2019 Baicalein is a bioactive flavone that is originally extracted from the root of Scutellaria baicalensis Georgi. This plant has long served as Chinese herbal medicine in the management of multiple diseases including inflammatory bowel diseases. Although it has been revealed that baicalein inhibits experimental colitis in mice, the molecular mechanisms ...
Xiancai Zhong +6 more
openaire +3 more sources
Sodium arsenite reduces severity of dextran sulfate sodium-induced ulcerative colitis in rats [PDF]
Journal of Zhejiang University SCIENCE B, 2008 The histopathological features and the associated clinical findings of ulcerative colitis (UC) are due to persistent inflammatory response in the colon mucosa. Interventions that suppress this response benefit UC patients. We tested whether sodium arsenite (SA) benefits rats with dextran sulfate sodium (DSS)-colitis.
Joshua J, Malago, Hortensia, Nondoli
openaire +2 more sources
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
The effects of apolipoprotein B depletion on HDL subspecies composition and function[S]
Journal of Lipid Research, 2016 HDL cholesterol (HDL-C) efflux function may be a more robust biomarker of coronary artery disease risk than HDL-C. To study HDL function, apoB-containing lipoproteins are precipitated from serum.
W. Sean Davidson +10 more
doaj +1 more source
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
Advanced Science, EarlyView.ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source