Results 71 to 80 of about 98,592 (289)

Microplastic effects on mouse colon in normal and colitis conditions: A literature review [PDF]

PeerJ
Background Taking into account the global spread of microplastic (MP) pollution, the problem of the MP impact on human health is relevant. MP enters the organism predominantly with water and food, and is mostly detected in the large intestine. Therefore,
Natalia Zolotova, Dzhuliia Dzhalilova, Ivan Tsvetkov, Maria Silina, Nikolai Fokichev, Olga Makarova   +5 more
doaj   +2 more sources

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Over-Expression of CD200 Protects Mice from Dextran Sodium Sulfate Induced Colitis. [PDF]

PLoS ONE, 2016
CD200:CD200 receptor (CD200R) interactions lead to potent immunosuppression and inhibition of autoimmune inflammation. We investigated the effect of "knockout"of CD200 or CD200R, or over-expression of CD200, on susceptibility to dextran sodium sulfate ...
Zhiqi Chen, Kai Yu, Fang Zhu, Reginald Gorczynski   +3 more
doaj   +1 more source

Paramagnetic, Silicon Quantum Dots for Magnetic Resonance and Two-Photon Imaging of Macrophages [PDF]

, 2010
Quantum dots (QDs) are an attractive platform for building multimodality imaging probes, but the toxicity for typical cadmium QDs limits enthusiasm for their clinical use.
Kauzlarich, Susan M., Louie, Angelique Y., Ma, Xuchu, Pantazis, Periklis, Tu, Chuqiao   +4 more
core   +3 more sources

Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium–Induced Colitis

Inflammatory Bowel Diseases, 2022
AbstractBackgroundDisruption of central circadian rhythms likely mediated by changes in microbiota and a decrease in gut-derived metabolites like short chain fatty acids (SCFAs) negatively impacts colonic barrier homeostasis. We aimed to explore the effects of isolated peripheral colonic circadian disruption on the colonic barrier in a mouse model of ...
Sarah B Jochum, Phillip A Engen, Maliha Shaikh, Ankur Naqib, Sherry Wilber, Shohreh Raeisi, Lijuan Zhang, Shiwen Song, Gabriella Sanzo, Vijit Chouhan, Frank Ko, Zoe Post, Laura Tran, Vivian Ramirez, Stefan J Green, Khashayarsha Khazaie, Dana M Hayden, Mark J Brown, Robin M Voigt, Christopher B Forsyth, Ali Keshavarzian, Garth R Swanson   +21 more
openaire   +2 more sources

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Dextran sodium sulfate (DSS) induces necrotizing enterocolitis-like lesions in neonatal mice. [PDF]

PLoS ONE, 2017
Necrotizing enterocolitis (NEC) is an inflammatory bowel disease of preterm human newborns with yet unresolved etiology. An established neonatal murine model for NEC employs oral administration of lipopolysaccharides (LPS) combined with hypoxia ...
Marco Ginzel, Xiaoyan Feng, Joachim F Kuebler, Christian Klemann, Yi Yu, Reinhard von Wasielewski, Joon-Keun Park, Mathias W Hornef, Gertrud Vieten, Benno M Ure, Torsten Kaussen, Jan Hendrik Gosemann, Steffi Mayer, Anne Suttkus, Martin Lacher   +14 more
doaj   +1 more source

Method for separating biological cells [PDF]

, 1980
A method for separating biological cells by suspending a mixed cell population in a two-phase polymer system is described. The polymer system consists of droplet phases with different surface potentials for which the cell populations exhibit different ...
Brooks, D. E.
core   +1 more source

Helminths in the gastrointestinal tract 1 as modulators of immunity and pathology [PDF]

, 2017
Helminth parasites are highly prevalent in many low- and middle-income countries, in which inflammatory bowel disease and other immunopathologies are less frequent than in the developed world.
Fleming, John O., Maizels, Richard, Varyani, Fumi   +2 more
core   +1 more source

Glucosamine sulfate attenuates dextran sodium sulfate (DSS) induced colitis in mice

The FASEB Journal, 2013
Glucosamine is a widely used supplement among patients with osteoarthritis. Also, it has been shown that glucosamine exhibits anti‐inflammatory action through the suppression of neutrophil activation. In this study, efficacy of glucosamine supplementation to attenuates DSS‐induced colitis. C57BL/6 mice were separated into three groups (n=10/group).
Youn‐Kyung Bak, Johanna W. Lampe, Mi‐Kyung Sung   +2 more
openaire   +1 more source