Results 81 to 90 of about 809,759 (252)

Dextran fouling of polyethersulfone ultrafiltration membranesâCauses, extent and consequences [PDF]

, 2007
In a recent paper [Susanto, Ulbricht, J. Membr. Sci. 266 (2005) 132], we showed that dextran does foul polyethersulfone (PES) ultrafiltration (UF) membranes by contact of the solution with the membrane surface without flux through the membrane.
Franzka, Steffen, Susanto, Heru, Ulbricht, Mathias   +2 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

POSITIVE CORRELATION BETWEEN DISEASE ACTIVITY INDEX AND MATRIX METALLOPROTEINASES ACTIVITY IN A RAT MODEL OF COLITIS

Arquivos de Gastroenterologia
ContextInflammatory bowel disease, including ulcerative colitis and Crohn’s disease, comprising a broad spectrum of diseases those have in common chronic inflammation of the gastrointestinal tract, histological alterations and an increased activity ...
Luiz Gustavo de OLIVEIRA, André Luiz da CUNHA, Amaury Caiafa DUARTE, Maria Christina Marques Nogueira CASTAÑON, Júlio Maria Fonseca CHEBLI, Jair Adriano Kopke de AGUIAR   +5 more
doaj   +1 more source

Sasa quelpaertensis leaf extract suppresses dextran sulfate sodium-induced colitis in mice by inhibiting the proinflammatory mediators and mitogen-activated protein kinase phosphorylation

, 2021
Anti-inflammation; Dextran sulfate sodium; Mice; Sasa quelpaertensis Nakai leaf extract; Ulcerative ...
김유리
core   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation

, 2020
Ceramide synthase 5 is one of six enzymes that catalyze the production of ceramides from sphingosine or sphinganine. Ceramides are important components of cell membranes and act as signaling molecules.
Dominique Thomas, Sebastian Brachtendorf, Stephanie Oertel, Kerstin Birod, Khadija El-Hindi, Sandra Trautmann, Jennifer Christina Hartel, Olaf Utermöhlen, Thomas Ulshöfer, Andreas Weigert, Martin Krönke, Sabine Grösch   +11 more
core   +2 more sources

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Role of Sodium Phenylbutyrate and Suramin in the Prevention of Ulcerative Colitis Induced by Dextran Sulfate Sodium

Experimed
Objective: Ulcerative colitis is a relapsing inflammatory condition confined to the colonic mucosa in which persistent immune activation is accompanied by oxidative damage and epithelial disruption.
Cansu Özal Coşkun, Ecem Fatma Karaman, Sibel Özden, Engin Kaptan, Pelin Arda   +4 more
doaj   +1 more source

Bifidobacterium longum CCFM1206 Promotes the Biotransformation of Glucoraphanin to Sulforaphane That Contributes to Amelioration of Dextran-Sulfate-Sodium-Induced Colitis in Mice

Glucoraphanin, rich in broccoli seed extract (BSE), is generally inert but can be biotransformed into active sulforaphane by gut bacteria. This study aimed to screen probiotics with glucoraphanin-metabolizing ability and explore the effect of a ...
Qiuxiang Zhang (216630), Yan Jin (143500), Shumao Cui (1373328), Xin Tang (134573), Jiaying Wu (2000449), Bingyong Mao (1682746), Jianxin Zhao (640885), Hao Zhang (15339)   +7 more
core   +1 more source

Dietary Supplementation with a Low Dose of Polyphenol-Rich Grape Pomace Extract Prevents Dextran Sulfate Sodium-Induced Colitis in Rats

, 2016
Dietary Supplementation with a Low Dose of Polyphenol-Rich Grape Pomace Extract Prevents Dextran Sulfate Sodium-Induced Colitis in ...
Felgines, Catherine, VASSON, Marie-Paule, Joubert-Zakeyh, Juliette, Pereira, Bruno, Fraisse, Didier, Texier, Odile, Boussenna, Ahlem   +6 more
core   +1 more source