Results 101 to 110 of about 98,592 (289)

Protective role of TIGAR in dextran sulfate sodium-induced colitis

徐州医科大学学报
Objective To investigate the effect of TP53-induced glycolysis and apoptosis regulator (TIGAR) gene deletion on dextran sulfate sodium (DSS)-induced colitis in mice and its potential mechanisms.
TU Daman, LI Mei
doaj   +1 more source

Tetraspanin CD9 limits mucosal healing in experimental colitis [PDF]

, 2017
Tetraspanins are a family of proteins with four transmembrane domains that associate between themselves and cluster with other partner proteins, conforming a distinct class of membrane domains, the tetraspanin-enriched microdomains (TEMs).
Arduise, Barreiro, Barreiro, Berditchevski, Boucheix, Cario, Castro-Sanchez, Chami, Charrin, Cooper, Froslie, Fukata, Fukata, Gutiérrez-López, Hemler, Iizuka, Inui, Khor, Kiesler, Kovalenko, Kovalenko, Le Naour, Leung, Mombaerts, Murayama, Natsui, Neurath, Okayasu, Ovalle, Perse, Pineton de Chambrun, Playford, Podolsky, Powner, Rakoff-Nahoum, Rocha-Perugini, Rutgeerts, Shah, Shi, Sinha, Smith, Tai, Tai, Takeda, Tang, Toyo-oka, Williams, Yáñez-Mó   +47 more
core   +4 more sources

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

Stabilizing Water-in-Water Emulsions Using Oil Droplets

Molecules
The production of water-in-water emulsion droplets, the coalescence of which is prevented by adding oil-in-water micrometric droplets, is reported. Hexadecane (O) and cetyl trimethyl ammonium bromide (CTAB) were added to a W/W emulsion made of dextran ...
Jean-Paul Douliez, Laure Béven
doaj   +1 more source

Rapid RNA Exchange in Aqueous Two-Phase System and Coacervate Droplets [PDF]

, 2014
Compartmentalization in a prebiotic setting is an important aspect of early cell formation and is crucial for the development of an artificial protocell system that effectively couples genotype and phenotype. Aqueous two-phase systems (ATPSs) and complex
Hentrich, Christian, Jia, Tony Z., Szostak, Jack W.   +2 more
core   +2 more sources

Involvement of lymphocytes in dextran sulfate sodium-induced experimental colitis

World Journal of Gastroenterology, 2006
To investigate the roles of lymphocytes in the development of dextran sulfate sodium-induced colitis.Using various doses of dextran sulfate sodium (DSS), we induced colitis in wild-type B6 control and Rag-1 knockout (H-2b haplotype) mice, and evaluated the colitis in terms of symptomatic and histologic parameters, such as weight loss, survival ...
Tae Woon, Kim, Jae Nam, Seo, Young Ho, Suh, Hyo Jin, Park, Ju Hyun, Kim, Ji Young, Kim, Kwon Ik, Oh   +6 more
openaire   +2 more sources

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

IL-22–producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis [PDF]

, 2013
IL-22 plays an important role in mucosal epithelial cell homeostasis. Using a dextran sodium sulfate-induced mouse model of acute colitis, we observed an IL-23–dependent up-regulation of IL-22 in the middle and distal colon at the onset of epithelial ...
Chaplin, David D., Harbour, Stacey N., Lai, Jen-Feng, Lee, Yun Kyung, Maynard, Craig L., Ouyang, Wenjun, Weaver, Casey T., Zindl, Carlene L.   +7 more
core  

Outer envelope membranes from chloroplasts are isolated as right-side-out vesicles [PDF]

, 1992
Outer envelope membranes were isolated from purified chloroplasts of pea leaves. The sidedness of the vesicles was analyzed by (i) aqueous polymer-two phase partitioning, (ii) the effect of limited proteolysis on the outer-envelope proteins (OEP) 86 and ...
Eichacker, Susanne, Soll, Jürgen, Waegemann, Karin   +2 more
core   +1 more source

Kefir treatment ameliorates dextran sulfate sodium-induced colitis in rats

World Journal of Gastroenterology, 2015
To investigate the preventive effect of kefir on colitis induced with dextran sulfate sodium (DSS) in rats.Twenty-four male Wistar-albino rats were randomized into four groups: normal control, kefir-control, colitis, and kefir-colitis groups. Rats in the normal and kefir-control groups were administered tap water as drinking water for 14 d. Rats in the
ŞENOL, Altuğ, İşler, Mehmet, Sutcu, Recep, AKIN, METE, Cakir, Ebru, Ceyhan, Betul M., KOÇKAR, Muhammet Cem   +6 more
openaire   +3 more sources