Results 111 to 120 of about 64,315 (292)

Syringic Acid Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota

, 2023
Inflammatory bowel disease is known to be associated with alterations in gut microbiota. The bioactive compound syringic acid has been shown to alleviate inflammatory bowel disease, but its interaction with gut microbiota and mechanism of action remain ...
Ruoyu Shi (6715286), Chan Zhang (752696), Pengfei Gong (349607), Qiaoqiao Luo (5003582), Zhe Wu (582498), Wei Chen (23863), Chengtao Wang (2835524)   +6 more
core   +1 more source

Identification and validation of fecal complement component 3 and fibronectin as potential biomarkers for monitoring disease activity in ulcerative colitis based on a mouse model

Animal Models and Experimental Medicine, EarlyView.
This study demonstrated elevated levels of fecal component 3 (C3) and fibronectin (FN) in an ulcerative colitis (UC) mouse model. Importantly, fecal C3 exhibited a stronger correlation with disease activity than the clinically used fecal calprotectin (FC).
Yangyun Guo, Ziheng Yan, Jingyu Ye, Ruifu Yang, Yajun Song, Hui Yue, Yong Zhao   +6 more
wiley   +1 more source

Efeito anti-inflamatório da mistura de triterpenos pentacíclicos α,β-amirina no modelo de colite induzida pelo DSS em camundongos [PDF]

, 2013
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Trabalho de Conclusão de Curso submetido ao Curso de Ciências Biológicas da Universidade Federal de Santa Catarina para a obtenção do Grau de Bacharel em ...
Matos, Israel
core  

Sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice

Experimental and Therapeutic Medicine, 2013
Sodium 4-phenylbutyrate (PBA) exhibits anti-inflammatory effects by suppressing nuclear factor-κB (NF-κB) activation. In the present study, the effects of PBA on a mouse model of dextran sulfate sodium (DSS)-induced colitis were investigated. The therapeutic efficacy of PBA (150 mg/kg body weight) in DSS-induced colitis was assessed based on the ...
ONO, KAZUHIKO, NIMURA, SATOSHI, NISHINAKAGAWA, TAKUYA, HIDESHIMA, YUKO, ENJYOJI, MUNECHIKA, NABESHIMA, KAZUKI, NAKASHIMA, MANABU   +6 more
openaire   +3 more sources

Glucosamine sulfate attenuates dextran sodium sulfate (DSS) induced colitis in mice

The FASEB Journal, 2013
Glucosamine is a widely used supplement among patients with osteoarthritis. Also, it has been shown that glucosamine exhibits anti‐inflammatory action through the suppression of neutrophil activation. In this study, efficacy of glucosamine supplementation to attenuates DSS‐induced colitis. C57BL/6 mice were separated into three groups (n=10/group).
Youn‐Kyung Bak, Johanna W. Lampe, Mi‐Kyung Sung   +2 more
openaire   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

Maize Flavan-4-ols and Anthocyanins Alleviated Dextran Sulfate Sodium-Induced Colitis in Mice via Intestinal Barrier Function Restoration

, 2020
This study investigated the anti-inflammatory effects of anthocyanins and flavan-4-ols (precursor of phlobaphenes) within a whole-food matrix against dextran sulfate sodium (DSS)-induced colitis using four maize near-isogenic lines (NILs) that differ ...
Wu, Binning, Surinder Chopra, Lavanya Reddivari, Li, Shiyu, Anderson, Ruth, Chang, Haotian, Ruth Anderson, Shiyu Li, Chopra, Surinder, Binning Wu, Haotian Chang, Reddivari, Lavanya   +11 more
core   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Is dextran sulfate sodium a good inducer of acute experimental enteritis?

International Journal of Immunopathology and Pharmacology, 2019
Animal models play critical roles in exploring the pathogenesis of human diseases and designing novel therapeutic schemes. Acute experimental colitis (AEC) models have been reported to be established in mice principally by oral administration of dextran ...
Wei Chen, Jing Zhang, Chen Li, Quan Pan, Jingtong Wu, Lina Fan, Chunyan Chen, Xiaoqing Huang, Fei Teng, Jinshui Zhu   +9 more
doaj   +1 more source

Preparation of Hydrochlorothiazide Nanoparticles for Solubility Enhancement

Molecules, 2016
Nanoparticles can be considered as a useful tool for improving properties of poorly soluble active ingredients. Hydrochlorothiazide (Class IV of the Biopharmaceutical Classification System) was chosen as a model compound.
Eliska Vaculikova, Aneta Cernikova, Daniela Placha, Martin Pisarcik, Pavlina Peikertova, Katerina Dedkova, Ferdinand Devinsky, Josef Jampilek   +7 more
doaj   +1 more source