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Secondary effects induced by the colon carcinogen azoxymethane in BDIX rats
APMIS, 2004Azoxymethane (AOM) is claimed to be a colon‐specific carcinogen. In our studies, AOM was administered to adult BDIX/OrlIco rats by four weekly subcutaneous injections of 15 mg/kg body weight each – two periods of 2 weeks of AOM treatment separated by a one‐week break.
Kobaek-Larsen, Morten +2 more
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Green Tea Polyphenols Inhibit Colorectal Tumorigenesis in Azoxymethane-Treated F344 Rats
Nutrition and Cancer, 2017In studying the cancer-preventive activities of green tea polyphenols, we previously demonstrated that dietary administration of polyphenon E (PPE) inhibited the formation of aberrant crypt foci (ACF) in the colon of azoxymethane (AOM)-treated F344 rats. Herein, we reported cancer-preventive activity of PPE using colorectal cancer as an end point. F344
Xingpei, Hao +5 more
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Kinetics of methoxy-NNO-Azoxymethane hydrolysis in strong acids
Kinetics and Catalysis, 2011The kinetics of methoxy-NNO-azoxymethane (I) hydrolysis in concentrated solutions of strong acids (HBr, HCl, HClO4, and H2SO4) has been investigated by a manometric method. The gas evolution rate is described by the equation corresponding to two consecutive first-order reactions, with the rate constant of the second reaction considerably exceeding the ...
I. N. Zyuzin, D. B. Lempert
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Azoxymethane/Dextran Sodium Sulfate (AOM/DSS) Model of Colorectal Cancer
Recent progress in developing new vaccination strategies against cancer requires the production of complex and reliable animal models reflecting the complexity of the tumors with their microenvironment. Mice can be considered a good source due to low cost and ease of being genetically modified, inoculated with tumor cell lines or treated by chemicals ...De Robertis Mariangela, Signori Emanuela
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Synthesis of vinyloxy-NNO-azoxymethane
Russian Chemical Bulletin, 1998I. N. Zyuzin, G. N. Nechiporenko
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Cancer research, 1987
Epidemiological studies have shown an association between consumption of alcoholic beverages and carcinoma of the large bowel, but studies in experimental models of colonic carcinogenesis have yielded conflicting results. We assessed the effects on azoxymethane-induced colonic carcinogenesis of both timing of chronic dietary ethanol consumption ...
S R, Hamilton, O S, Sohn, E S, Fiala
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Epidemiological studies have shown an association between consumption of alcoholic beverages and carcinoma of the large bowel, but studies in experimental models of colonic carcinogenesis have yielded conflicting results. We assessed the effects on azoxymethane-induced colonic carcinogenesis of both timing of chronic dietary ethanol consumption ...
S R, Hamilton, O S, Sohn, E S, Fiala
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Determination of micronuclei by azoxymethane in mouse
Toxicology Letters, 2008Isela Alvarez-Gonzalez +2 more
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3165. Azoxymethane and colon carcinogenesis
Food and Cosmetics Toxicology, 1977openaire +1 more source