Results 251 to 260 of about 21,150 (298)
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Xanthohumol protects against Azoxymethane‐induced colorectal cancer in Sprague‐Dawley rats
Environmental Toxicology, 2019AbstractColorectal cancer (CRC) is a major health problem and third most common deaths in western world. Dietary interventions together with modified dietary style can prevent the CRC in humans. Xanthohumol (XHA), a polyphenol isolated from Humulus lupulus L. contains many beneficial effects.
Hualin Liu +3 more
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Green Tea Polyphenols Inhibit Colorectal Tumorigenesis in Azoxymethane-Treated F344 Rats
Nutrition and Cancer, 2017In studying the cancer-preventive activities of green tea polyphenols, we previously demonstrated that dietary administration of polyphenon E (PPE) inhibited the formation of aberrant crypt foci (ACF) in the colon of azoxymethane (AOM)-treated F344 rats. Herein, we reported cancer-preventive activity of PPE using colorectal cancer as an end point. F344
Xingpei, Hao +5 more
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Inhibition of azoxymethane-induced intestinal cancer by disulfiram
Cancer Letters, 1978Sprague--Dawley rats, both intact and colostomized animals, were given 24 weekly injections of azoxymethane. Rats were fed either Rat Purina Chow or the same diet plus 0.25% disulfiram. In the intact animals, disulfiram reduced tumors from an average of 6.3 to 0.95. The number of rats developing tumors was reduced from 100% to 60%.
N D, Nigro, R L, Campbell
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Hypergastrinemia in rats with azoxymethane‐induced colon cancers
International Journal of Cancer, 1995AbstractGastrin has been suggested to be involved in the promotion and progression of colon cancer. Mice colon cancers and colon‐carcinoma cell lines are stimulated to grow by gastrin, and gastrin receptors have been found in the majority of human colon‐tumor specimens.
L, D'Agostino +9 more
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ChemInform Abstract: Synthesis of Vinyloxy‐NNO‐azoxymethane.
ChemInform, 1999AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
I. N. Zyuzin, G. N. Nechiporenko
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Inhibition of Azoxymethane-Induced Colon Cancer by Orange Juice
Nutrition and Cancer, 2000Previous research has shown that hesperidin, a flavanone glycoside in orange juice, inhibits colon carcinogenesis and that feeding double-strength orange juice delays the onset of chemically induced mammary cancer in rats. This study determined whether feeding single-strength, pasteurized orange juice would inhibit azoxymethane (AOM)-induced colon ...
Y, Miyagi +3 more
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Transglutaminase in azoxymethane-induced colon cancer in the rat
Digestive Diseases and Sciences, 1995A widespread from of transglutaminase, tissue transglutaminase, has been identified in a number of mammalian cell types, both normal and transformed cells; its biological role is not well understood. We investigated the effect of experimentally induced colon cancer on transglutaminase activity in the rat. Azoxymethane (15 mg/kg for six weeks), given by
G. D'ARGENIO +7 more
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The effect of deuterium substitution on carcinogenesis by azoxymethane
Cancer Letters, 1984Azoxymethane was synthesized labeled with deuterium in one or other of the two methyl groups. Groups of 20 male F344 rats were given either 4 mg or 1 mg per week of each of the labeled compounds or of unlabeled azoxymethane each week in drinking water, for 30 weeks, after which the animals were kept until they died.
W, Lijinsky, M D, Reuber, J E, Saavedra
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Effect of black tea on azoxymethane-induced colon cancer
Carcinogenesis, 1998Two sets of experiments on the role of tea in azoxymethane (AOM) induced colon cancer were performed. The first test involved male F344 rats given 1.25% solutions of black tea beginning at 5 weeks of age and ending at 51 days of age. At 6 and 7 weeks of age, they received 15 mg/kg AOM and were held for 50 weeks. Another group received the AOM dosage at
J H, Weisburger +6 more
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AZOXYCOMPOUNDS: I. THE PHOTOLYSIS OF AZOXYMETHANE
Canadian Journal of Chemistry, 1964A study of the photolysis of azoxymethane has been made. The reaction products include nitrogen, nitrous oxide, methane, and ethane. The ratio N2:N2O is independent of temperature and two primary photolytic processes are postulated to account for this fact.
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