Results 31 to 40 of about 2,475 (111)

Impaired Volume Regulation and Electrophysiology of Astrocytes In Situ in a Mouse Model for Megalencephalic Leukoencephalopathy With Subcortical Cysts

Glia, EarlyView.
Cell culture studies show disrupted astrocyte physiology in the leukodystrophy MLC. Are intact astrocytes similarly affected? This study on astrocytes in MLC mouse brain slices confirms and extends in vitro studies on altered astrocyte physiology. ABSTRACT Electrical signaling, driven by ion fluxes between intra‐ and extracellular compartments, is ...
Sven Kerst, Nina Meesters, Tim S. Heistek, Marjo S. van der Knaap, Huibert D. Mansvelder, Rogier Min   +5 more
wiley   +1 more source

Application of computer vision for off‐highway vehicle route detection: A case study in Mojave desert tortoise habitat

Remote Sensing in Ecology and Conservation, EarlyView.
Our study leverages advanced computer vision models, which we trained on a unique collection of geospatial imagery, to detect off‐highway vehicle (OHV) routes in the Mojave Desert, a critical habitat for the threatened Mojave desert tortoise (Gopherus agassizii).
Alexander J. Robillard, Madeline Standen, Noah Giebink, Mark Spangler, Amy C. Collins, Brian Folt, Andrew Maguire, Elissa M. Olimpi, Brett G. Dickson   +8 more
wiley   +1 more source

Targeted siRNA Delivery Using Cetuximab‐Conjugated Starch for Epidermal Growth Factor Receptor‐Driven Head and Neck Squamous Cell Carcinoma

Small Science, EarlyView.
A starch‐based carrier conjugated to cetuximab enables targeted siRNA delivery to epidermal growth factor receptor‐overexpressing tumors. The complexes exhibit dual passive and active tumor targeting, effective cellular uptake, and gene silencing, offering a versatile platform for RNA therapeutics in head and neck cancer.
Chen Benafsha, Limor Cohen, Leah Shimonov, Riki Goldbart, Tamar Traitel, Eliz Amar‐Lewis, Ramesh Chintakunta, Manu Parasad, Uzi Hadad, Moshe Elkabets, Joseph Kost   +10 more
wiley   +1 more source

Spatiotemporal Interrogation of Single Spheroids Using Multiplexed Nanoplasmonic‐Fluorescence Imaging

Small Methods, EarlyView.
This work introduces a multiplexed imaging platform that integrates nanoplasmonic sensing with fluorescence microscopy for concomitant monitoring of extraspheroid secretions and intraspheroid features over extended periods with spatiotemporal resolution.
Saeid Ansaryan, Yung‐Cheng Chiang, Yen‐Cheng Liu, Jiayi Tan, Luis Francisco Lorenzo‐Martín, Matthias P. Lutolf, Genrich Tolstonog, Hatice Altug   +7 more
wiley   +1 more source

An ecological vulnerability index to assess impacts of offshore wind facilities on migratory songbirds

Journal of Applied Ecology, EarlyView.
Our methodology is readily applicable to other regions where offshore wind (OSW) development is planned and songbird migration is common, allowing research and monitoring activities to be targeted to species most likely to be negatively affected by OSW facility encounters. Abstract As offshore wind (OSW) energy expands globally, migratory songbirds are
Leon A. Green‐Tkacenko, Michael C. Allen, Julie L. Lockwood   +2 more
wiley   +1 more source

Obligatory symbiotic Wolbachia endobacteria are absent from Loa loa [PDF]

, 2003
BACKGROUND: Many filarial nematodes harbour Wolbachia endobacteria. These endobacteria are transmitted vertically from one generation to the next. In several filarial species that have been studied to date they are obligatory symbionts of their hosts ...
Bain, Odile, Bazzocchi, Chiara, Büttner, Dietrich W, Fischer, Peter, Wanji, Samuel   +4 more
core   +2 more sources

TRAPPC2l Participates in Male Germ Cell Development by Regulating Cell Division

Cell Proliferation, EarlyView.
Trappc2l is crucial for maintaining the quiescent state of male gonocytes. In the absence of Trappc2l, the quiescent state of gonocytes is disrupted, leading to premature and abnormal initiation of meiosis, which consequently results in subsequent abnormalities in sperm development. ABSTRACT TRAPPC2L is a core subunit of the Transport Protein Particle (
Mengyue Wang, Jiayi Li, Bowen Liu, Zhiming Shen, Min Chen, Xiuhong Cui, Hongbin Liu, Fei Gao, Han Zhao   +8 more
wiley   +1 more source

Boston University Percussion Ensemble, November 6, 2009 [PDF]

, 2009
This is the concert program of the Boston University Percussion Ensemble performance on Friday, November 6, 2009 at 7:30 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts. Works performed were Le Corps Á Corps by
School of Music, Boston University
core  

NSun2‐Mediated tsRNAs Alleviate Liver Fibrosis via FAK Dephosphorylation

Cell Proliferation, EarlyView.
NSun2 deficiency inhibited sinusoidal capillarization, alleviating liver fibrosis. Reduced NSun2 expression led to alterations in the functional tsRNAs tRF‐1‐S25 and tRF‐5‐V31, which regulate sinusoidal capillarization by targeting key proteins, including DUSP1 and FAK – crucial clinical targets – offering a novel RNA‐based therapeutic approach for ...
Pengcheng Li, Sunyang Ying, Yu Zou, Xin Wang, Runxue Zhang, Cheng Huang, Moyu Dai, Kai Xu, Guihai Feng, Xin Li, Haiping Jiang, Zhikun Li, Ying Zhang, Wei Li, Qi Zhou   +14 more
wiley   +1 more source

Ultrastructural Insights Into a Candidatus Parilichlamydia sp. Infection of Gill Goblet Cells in Greater Amberjack

Journal of Fish Diseases, EarlyView.
ABSTRACT Despite recent genomic studies and increased molecular data, epitheliocystis remains an enigmatic fish disease with no experimental in vitro or in vivo models to aid the advancement of research. In this study, we revert to a classical microscopical approach and screen with the electron microscope the epitheliocystis lesions caused by a Ca ...
Maria Chiara Cascarano, Papadogiorgaki Sevasti, Pantelis Katharios   +2 more
wiley   +1 more source